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Active Recombinant Rat Fgf9

Cat.No. : Fgf9-586R
Product Overview : Recombinant Rat Fgf9 produced in E. coli is approximately 23.1 kDa, a single non-glycosylated polypeptide chain containing 205 amino acids.
  • Specification
  • Gene Information
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Description : Fibroblast growth factor 9 (FGF-9) belongs to the large FGF family which has at least 23 members. All FGF family members are heparin binding growth factors with a core 120 amino acid (a.a.) FGF domain that allows for a common tertiary structure. FGF-9 targets glial cells, astrocytes cells and other cells that express the FGFR 1c, 2c, 3b, 3c, and 4.
Source : E. coli
Species : Rat
Form : Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris, 400 mM NaCl, pH8.0.
Bio-activity : Fully biologically active when compared to standard. The ED 50 determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1 ng/ml, corresponding to a specific activity of >1.0 × 10^6 IU/mg.
Molecular Mass : 23.1 kDa
AA Sequence : LGEVGSYFGV QDAVPFGNVP VLPVDSPVLL SDHLGQSEAG GLPRGPAVTD LDHLKGILRR RQLYCRTGFH LEIFPNGTIQ GTRKDHSRFG ILEFISIAVG LVSIRGVDSG LYLGMNEKGE LYGSEKLTQE CVFREQFEEN WYNTYSSNLY KHVDTGRRYY VALNKDGTPR EGTRTKRHQK FTHFLPRPVD PDKVPELYKD ILSQS
Endotoxin : Less than 1 EU/μg of rRtFGF-9-1 as determined by LAL method.
Purity : >95% by SDS-PAGE and HPLC analyses.
Usage : This material is for research, laboratory or further evaluation purposes. NOT FOR HUMAN USE.
Storage : This lyophilized preparation is stable at 2-8 centigrade, but should be kept at -20 centigrade for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 centigrade. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 centigrade to -70 centigrade. Avoid repeated freeze/thaw cycles.
Reconstitution : We recommend that this vial be briefy centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at< -20 centigrade. further dilutions should be made in appropriate buffered solutions.>
Gene Name : Fgf9 fibroblast growth factor 9 [ Rattus norvegicus ]
Official Symbol : Fgf9
Synonyms : FGF9; fibroblast growth factor 9; GAF; FGF-9; HBGF-9; glia-activating factor;
Gene ID : 25444
mRNA Refseq : NM_012952
Protein Refseq : NP_037084
Pathway : Downstream signaling of activated FGFR, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1c ligand binding and activation, organism-specific biosystem; FGFR2 ligand binding and activation, organism-specific biosystem; FGFR2c ligand binding and activation, organism-specific biosystem; FGFR3 ligand binding and activation, organism-specific biosystem;
Function : fibroblast growth factor receptor binding; growth factor activity; heparin binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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