Active Recombinant Human ICOS Protein, His tagged

• Cat.No.: ICOS-22H
• Product Overview: Recombinant Human ICOS protein (Glu21-Lys140) with His tag was expressed in Chinese Hamster Ovary cell line.

Specification

• Species: Human
• Source: CHO
• Tag: His
• Protein Length: 21-140 aa
• Description: The protein encoded by this gene belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.
• N-terminal Sequence Analysis: Glu21
• Bio-activity: Measured by its binding ability in a functional ELISA. When Recombinant Human B7-H2 Fc Chimera is coated at 0.5 μg/mL, 100 μL/well, Recombinant Human ICOS binds with an ED50 of 0.7-3.5 ng/mL.
• Molecular Mass: 15 kDa
• Endotoxin: < 0.1 EU/μg by LAL
• Purity: > 95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie Blue Staining.
• Storage: 12 months from date of receipt, ≤ -20 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, ≤ -20 centigrade under sterile conditions after reconstitution.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
• Reconstitution: Reconstitute at 200 μg/mL in PBS.
• Shipping: The product is shipped at ambient temperature.

Gene Information

• Gene ID: 29851
• Gene Name: ICOS inducible T-cell co-stimulator [ Homo sapiens (human) ]
• Official Symbol: 29851
• Synonyms: ICOS; inducible T-cell co-stimulator; inducible T-cell costimulator; activation inducible lymphocyte immunomediatory molecule; AILIM; CD278; inducible costimulator; activation-inducible lymphocyte immunomediatory molecule; CVID1; MGC39850
• mRNA Refseq: NM_012092
• Official Symbol 2: ICOS
• Gene ID 2: 29851
• Gene Name 2: ICOS inducible T-cell co-stimulator [ Homo sapiens (human) ]
• mRNA Refseq 2: NM_012092
• Protein Refseq 2: NP_036224
• MIM 2: 604558
• UniProt ID 2: Q9Y6W8