Recombinant Human IL17D Protein, GST-tagged

Cat.No. : IL17D-5206H
Product Overview : Human IL27 full-length ORF ( AAH62422.1, 1 a.a. - 243 a.a.) recombinant protein with GST-tag at N-terminal.
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Description : The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 53.9 kDa
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
SDS-PAGE: 12.5% SDS-PAGE Stained with Coomassie Blue
Gene Name : IL17D interleukin 17D [ Homo sapiens (human) ]
Official Symbol : IL17D
Synonyms : IL27; interleukin 27; IL17D; interleukin 17D; IL-17D; interleukin-17D
Gene ID : 53342
mRNA Refseq : NM_138284
Protein Refseq : NP_612141
MIM : 607587
UniProt ID : Q8TAD2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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Q&As (10)

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What methodologies are employed to explore the role of IL17D in neuroinflammation and its potential implications in neurological disorders? 05/09/2022

Neuroinflammation models, neuronal cell assays, and CNS analysis explore IL17D's role in neurological contexts.

What techniques are used to characterize the potential pro-tumor or anti-tumor effects of IL17D in cancer development and progression? 11/03/2021

Tumor xenografts, immune cell infiltration analysis, and gene expression profiling dissect IL17D's role in cancer.

How do researchers decipher the distinct roles of IL17D compared to other IL17 family members in immune responses? 03/31/2020

Functional assays, knockout models, and gene expression analyses distinguish IL17D's unique roles.

How is the interaction between IL17D and the gut microbiota investigated, and what are the implications for intestinal homeostasis? 11/24/2019

Microbiota sequencing, gnotobiotic models, and immune cell profiling investigate IL17D-gut microbiota interactions.

How are the effects of IL17D modulation on autoimmune diseases investigated using experimental models and patient samples? 11/12/2019

Animal models, patient samples, and genetic studies elucidate IL17D's involvement in autoimmune diseases.

Can you explain the experimental designs used to study the involvement of IL17D in wound healing and tissue regeneration? 03/17/2018

Wound healing assays, tissue regeneration studies, and histological analyses examine IL17D's effects on tissue repair.

What experimental techniques are employed to investigate the signaling pathways triggered by IL17D and its potential crosstalk with other cytokines? 03/31/2017

Signal transduction assays, phosphoproteomics, and cytokine profiling reveal IL17D's signaling pathways.

What molecular approaches are utilized to assess IL17D's impact on host defense against infections and regulation of mucosal immunity? 03/06/2017

Cell culture models, infection assays, and epithelial barrier assessments uncover IL17D's impact on host defense.

Could you elaborate on the strategies used to study IL17D's contribution to tissue-specific immune cell activation and recruitment? 01/22/2017

Flow cytometry, chemotaxis assays, and adoptive transfer experiments probe IL17D-mediated immune responses.

How are the therapeutic applications of IL17D modulation studied, and what approaches are taken to validate its potential as a therapeutic target? 01/01/2017

Therapeutic antibody testing, RNA interference, and animal disease models validate IL17D as a potential therapy.

Customer Reviews (3)

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    Effective in Th9 differentiation.


      Suitable for ELISA.


        High bioactivity.

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