Recombinant Human IL17D Protein, GST-tagged
Cat.No. : | IL17D-5206H |
Product Overview : | Human IL27 full-length ORF ( AAH62422.1, 1 a.a. - 243 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 53.9 kDa |
AA Sequence : | MGQTAGDLGWRLSLLLLPLLLVQAG VWGFPRPPGRPQLSLQELRREFTVS LHLARKLLAEVRGQAHRFAESHLPG VNLYLLPLGEQLPDVSLTFQAWRRL SDPERLCFISTTLQPFHALLGGLGT QGRWTNMERMQLWAMRLDLRDLQRH LRFQVLAAGFNLPEEEEEEEEEEEE ERKGLLPGALGSALQGPAQVSWPQL LSTYRLLHSLELVLSRAVRELLLLS KAGHSVWPLGFPTLSPQP |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | IL17D interleukin 17D [ Homo sapiens (human) ] |
Official Symbol : | IL17D |
Synonyms : | IL27; interleukin 27; IL17D; interleukin 17D; IL-17D; interleukin-17D |
Gene ID : | 53342 |
mRNA Refseq : | NM_138284 |
Protein Refseq : | NP_612141 |
MIM : | 607587 |
UniProt ID : | Q8TAD2 |
Products Types
◆ Lysates | ||
IL17D-852HCL | Recombinant Human IL17D cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewEffective in Th9 differentiation.
Suitable for ELISA.
High bioactivity.
Q&As (10)
Ask a questionNeuroinflammation models, neuronal cell assays, and CNS analysis explore IL17D's role in neurological contexts.
Tumor xenografts, immune cell infiltration analysis, and gene expression profiling dissect IL17D's role in cancer.
Functional assays, knockout models, and gene expression analyses distinguish IL17D's unique roles.
Microbiota sequencing, gnotobiotic models, and immune cell profiling investigate IL17D-gut microbiota interactions.
Animal models, patient samples, and genetic studies elucidate IL17D's involvement in autoimmune diseases.
Wound healing assays, tissue regeneration studies, and histological analyses examine IL17D's effects on tissue repair.
Signal transduction assays, phosphoproteomics, and cytokine profiling reveal IL17D's signaling pathways.
Cell culture models, infection assays, and epithelial barrier assessments uncover IL17D's impact on host defense.
Flow cytometry, chemotaxis assays, and adoptive transfer experiments probe IL17D-mediated immune responses.
Therapeutic antibody testing, RNA interference, and animal disease models validate IL17D as a potential therapy.
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