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Recombinant Human IL18BP Protein, Fc-tagged

Cat.No. : IL18BP-316H
Product Overview : Recombinant human IL18BP protein with Fc tag was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Source : HEK293
Species : Human
Tag : Fc
Form : Lyophilized
Molecular Mass : 44.3 kDa
Protein Length : 194
AA Sequence : MTMRHNWTPDLSPLWVLLLCAHVVT LLVRATPVSQTTTAATASVRSTKDP CPSQPPVFPAAKQCPALEVTWPEVE VPLNGTLSLSCVACSRFPNFSILYW LGNGSFIEHLPGRLWEGSTSRERGS TGTQLCKALVLEQLTPALHSTNFSC VLVDPEQVVQRHVVLAQLWAGLRAT LPPTQEALPSSHSSPQQQG
Purity : > 98%
Applications : WB; ELISA; FACS; FC
Stability : This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
Storage : At -20 centigrade.
Concentration : 1 mg/mL
Storage Buffer : PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
Reconstitution : Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.
Gene Name : IL18BP interleukin 18 binding protein [ Homo sapiens (human) ]
Official Symbol : IL18BP
Synonyms : IL18BP; interleukin 18 binding protein; interleukin-18-binding protein; IL18BPa; MC51L 53L 54L homolog gene product; IL-18BP; tadekinig-alfa; MC51L-53L-54L homolog gene product;
Gene ID : 10068
mRNA Refseq : NM_001039659
Protein Refseq : NP_001034748
MIM : 604113
UniProt ID : O95998

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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