Recombinant Human Interleukin 18 Binding Protein
Cat.No. : | IL18BP-1656H |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL18BP-1656H |
Description : | IL-18-binding protein (IL-18BP) is a secreted glycoprotein that functions as a natural anti-inflammatory and immunosuppressive molecule neutralizing the effects of high IL18 levels during inflammation. There are four variants of IL-18BP and IL18BPa is the predominant form showing the highest affinity towards IL18. that IL-18 BPa:Fc has the potential to amplify anti-inflammatory actions of immunosuppressive drugs, and thus may prove to be a valuable novel pharmacological component in the treatment of human autoimmune diseases. |
Molecular Weight : | The predicted molecular weight of Recombinant Human IL-18 BPa is Mr 44.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 65-75 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | IL18BP interleukin 18 binding protein [Homo sapiens ] |
Synonyms : | IL18BP; interleukin 18 binding protein; tadekinig-alfa; IL18BPa; OTTHUMP00000179143; MC51L-53L-54L homolog gene product; IL-18BP; OTTHUMP00000179141; Tadekinig-alfa;Interleukin-18-binding protein |
Gene ID : | 10068 |
mRNA Refseq : | NM_001039659 |
Protein Refseq : | NP_001034748 |
MIM : | 604113 |
UniProt ID : | O95998 |
Chromosome Location : | 11q13 |
Function : | interleukin-18 binding; receptor antagonist activity |
Products Types
◆ Recombinant Protein | ||
IL18BP-252I | Active Recombinant Human IL18BP Protein | +Inquiry |
IL18BP-315H | Recombinant Human IL18BP Protein, His-tagged | +Inquiry |
IL18BP-56C | Active Recombinant Cynomolgus Monkey IL18BP Protein, His-tagged | +Inquiry |
IL18BP-2058R | Recombinant Rhesus Macaque IL18BP Protein, His (Fc)-Avi-tagged | +Inquiry |
Il18bp-142M | Recombinant Mouse Il18bp Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IL18BP-2918HCL | Recombinant Human IL18BP cell lysate | +Inquiry |
IL18BP-2674MCL | Recombinant Mouse IL18BP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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