Recombinant Human Interleukin 18 Binding Protein IL18BP-1656H

Recombinant Human Interleukin 18 Binding Protein

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Cat.No. : IL18BP-1656H Optional Service: Optional requirements on this protein
Description : IL-18-binding protein (IL-18BP) is a secreted glycoprotein that functions as a natural anti-inflammatory and immunosuppressive molecule neutralizing the effects of high IL18 levels during inflammation. There are four variants of IL-18BP and IL18BPa is the predominant form showing the highest affinity towards IL18. that IL-18 BPa:Fc has the potential to amplify anti-inflammatory actions of immunosuppressive drugs, and thus may prove to be a valuable novel pharmacological component in the treatment of human autoimmune diseases.
Molecular Weight : The predicted molecular weight of Recombinant Human IL-18 BPa is Mr 44.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 65-75 kDa.
Source : Mammalian cells
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : IL18BP interleukin 18 binding protein [Homo sapiens ]
Synonyms : IL18BP; interleukin 18 binding protein; tadekinig-alfa; IL18BPa; OTTHUMP00000179143; MC51L-53L-54L homolog gene product; IL-18BP; OTTHUMP00000179141; Tadekinig-alfa;Interleukin-18-binding protein
Gene ID : 10068
mRNA Refseq : NM_001039659
Protein Refseq : NP_001034748
MIM : 604113
UniProt ID : O95998
Chromosome Location : 11q13
Function : interleukin-18 binding; receptor antagonist activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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