- Cynomolgus Monkey(1)
- Human(10)
- Mouse(7)
- Rat(1)
- Rhesus Macaque(1)
Recombinant Human Interleukin 18 Binding Protein
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Cat.No. : | IL18BP-1656H Optional Service: Optional requirements on this protein |
Description : | IL-18-binding protein (IL-18BP) is a secreted glycoprotein that functions as a natural anti-inflammatory and immunosuppressive molecule neutralizing the effects of high IL18 levels during inflammation. There are four variants of IL-18BP and IL18BPa is the predominant form showing the highest affinity towards IL18. that IL-18 BPa:Fc has the potential to amplify anti-inflammatory actions of immunosuppressive drugs, and thus may prove to be a valuable novel pharmacological component in the treatment of human autoimmune diseases. |
Molecular Weight : | The predicted molecular weight of Recombinant Human IL-18 BPa is Mr 44.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 65-75 kDa. |
Source : | Mammalian cells |
State Of Matter : | Lyophilized. |
Purity : | >95% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | IL18BP interleukin 18 binding protein [Homo sapiens ] |
Synonyms : | IL18BP; interleukin 18 binding protein; tadekinig-alfa; IL18BPa; OTTHUMP00000179143; MC51L-53L-54L homolog gene product; IL-18BP; OTTHUMP00000179141; Tadekinig-alfa;Interleukin-18-binding protein |
Gene ID : | 10068 |
mRNA Refseq : | NM_001039659 |
Protein Refseq : | NP_001034748 |
MIM : | 604113 |
UniProt ID : | O95998 |
Chromosome Location : | 11q13 |
Function : | interleukin-18 binding; receptor antagonist activity |
◆ Recombinant Protein
IL18BP-56C | Recombinant Cynomolgus Monkey IL18BP Protein, His-tagged | +Inquiry |
IL18BP-75H | Recombinant Human IL18BP Protein | +Inquiry |
Il18bp-1578R | Recombinant Rat Il18bp protein, His-tagged | +Inquiry |
IL18BP-162H | Recombinant Human IL18BP protein, Fc-tagged | +Inquiry |
Il18bp-8339M | Recombinant Mouse Il18bp | +Inquiry |
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◆ Lysates
IL18BP-2674MCL | Recombinant Mouse IL18BP cell lysate | +Inquiry |
IL18BP-2918HCL | Recombinant Human IL18BP cell lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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