Active Recombinant Human IL28A Protein, Animal Free
| Cat.No. : | IL28A-33H |
| Product Overview : | Recombinant Human IL28A Protein without tag was expressed in Human cells. Animal Free and Xeno Free |
- Specification
- Gene Information
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| Description : | IL-28A, also named interferon λ2 (IFNλ2), belongs to the type III interferon protein family, which is distinct from the type I IFNs. IL-28A is induced by virus infection or double stranded RNA. IL-28A acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. IL-28A has antiviral, antitumor and immunomodulatory activities, plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. |
| Source : | Human cells |
| Species : | Human |
| Bio-activity : | The activity was measured by its anti-virus function in A549 cells (human lung adenocarcinoma epithelial cell line) infected with encephalomyocarditis (EMC) virus. |
| Molecular Mass : | 24 kDa |
| Endotoxin : | <0.5 EU/ μg |
| Purity : | High Purity, >95% by SDS-PAGE |
| Stability : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -80 centigrade under sterile conditions after reconstitution. |
| Storage Buffer : | Lyophilized from a 0.2 μm filtered solution in PBS without carrier protein |
| Reconstitution : | Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. |
| Gene Name : | IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens (human) ] |
| Official Symbol : | IL28A |
| Synonyms : | IL28A; interleukin 28A (interferon, lambda 2); interleukin 28A; interleukin-28A; IFNL2; IL 28A; IFN-lambda-2; cytokine Zcyto20; interferon lambda 2; interferon lambda-2; interferon-lambda 2; IL-28A; |
| Gene ID : | 282616 |
| mRNA Refseq : | NM_172138 |
| Protein Refseq : | NP_742150 |
| MIM : | 607401 |
| UniProt ID : | Q8IZJ0 |
Products Types
| ◆ Lysates | ||
| IL28A-5229HCL | Recombinant Human IL28A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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