Active Recombinant Human IL28A protein, His-tagged

• Cat.No.: IFNL2-459H
• Product Overview: Recombinant Human IL28A protein(Val26-Val200)(NP_742150.1), fused with His tag, was expressed in Yeast.

Specification

• Source: Yeast
• Species: Human
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Bio-activity: Measured in antiviral assays using HepG2 cells infected with vesicular stomatitis virus. The ED50 for this effect is 1.7-6.8 μg/mL.
• Molecular Mass: The recombinant human IFNL2 consists 185 amino acids and predicts a molecular mass of 21.1 kDa.
• Protein Length: Val26-Val200
• Purity: > 90 % as determined by SDS-PAGE.
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens ]
• Official Symbol: IL28A
• Synonyms: IL28A; interleukin 28A (interferon, lambda 2); interleukin 28A; interleukin-28A; IFNL2; IL 28A; IFN-lambda-2; cytokine Zcyto20; interferon lambda 2; interferon lambda-2; interferon-lambda 2; IL-28A
• Gene ID: 282616
• mRNA Refseq: NM_172138
• Protein Refseq: NP_742150
• MIM: 607401
• UniProt ID: Q8IZJ0

Reviews

11/15/2022

No need to prepare a special environment, storage conditions are very simple, can be stored for a long time.

10/04/2020

Very stable, strong anti-pollution ability, the experimental results are very good.

07/16/2019

The labeling effect is very good, and fluorescent labeling can be carried out.

Q&As

What is the main mechanism of action of IL28A?

It can enhance the body's immunity to pathogens by activating the immune system.

What is the role IL28A on the immune system?

IL28A regulates the activity and differentiation of immune cells and enhances the function of the immune system.

What are the pharmacokinetic characteristics of IL28A?

It has a long half-life and low clearance, which can maintain a stable plasma concentration.

How's the progress of clinical trials of IL28A?

IL28A is undergoing several clinical trials and is currently showing some efficacy.

How the synthesis and purification method of IL28A?

This protein is usually synthesized using recombinant DNA technology and purified by column chromatography and other methods.

What are the application prospects of IL28A in tumor therapy?

IL28A can regulate immune response and enhance anti-tumor immunity in tumor therapy.