Active Recombinant Human IL28A, MIgG2a Fc-tagged IL28A-311H

Active Recombinant Human IL28A, MIgG2a Fc-tagged

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Active Recombinant Human IL28A, MIgG2a Fc-tagged

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Cat.No. : IL28A-311H Optional Service: Optional requirements on this protein
Product Overview : The extracellular domain of human IL-28A (AAI13582.1) (Val26-Val200) is fused to the N-terminus of the Fc region of mouse IgG2a was expressed in CHO cell.
Description : This gene encodes a cytokine distantly related to type I interferons and the IL-10 family. This gene, interleukin 28B (IL28B), and interleukin 29 (IL29) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA)
Source : CHO cell
Species : Human
Tag : MIgG2a Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured in an anti-viral assay.
Molecular Mass : 46KDa (monomer)
AA Sequence : Val26-Val200
Endotoxin : <0.06 eu/μg as determined by lal test.>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens ]
Official Symbol : IL28A
Synonyms : IL28A; interleukin 28A (interferon, lambda 2); interleukin 28A; interleukin-28A; IFNL2; IL 28A; IFN-lambda-2; cytokine Zcyto20; interferon lambda 2; interferon lambda-2; interferon-lambda 2; IL-28A;
Gene ID : 282616
mRNA Refseq : NM_172138
Protein Refseq : NP_742150
MIM : 607401
UniProt ID : Q8IZJ0
Chromosome Location : 19q13.13
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function : cytokine activity;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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