Active Recombinant Human Interleukin 28A
| Cat.No. : | IL28A-539H |
| Product Overview : | Recombinant human IL28A was expressed in E. coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
| Cat. No. : | IL28A-539H |
| Description : | IFN-lambda-1, -2, and -3 (also known as IL29, IL28A and IL28B respectively) are distantly related to the IL10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. |
| Source : | Human |
| Host : | E.coli |
| Form : | Supplied as a lyophilized powder. |
| Purity : | >98% pure by SDS PAGE and HPLC |
| Sequence : | Region of IFN Gamma 2 protein corresponding to amino acids PVARLHGALP DARGCHIAQF KSLSPQELQA FKRAKDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV. |
| Molecular Mass : | 19.6 kDa |
| Applications : | Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions |
| Endotoxin Levels : | Endotoxin level is less than 0.1 ng per ug (1 EU/ug). |
| Bioactivity : | Determined by its ability to activate STAT following receptor-ligand interaction. |
| Storage : | Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
| Gene Name : | IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens ] |
| Official Symbol : | IL28A |
| Synonyms : | IL28A; interleukin 28A (interferon, lambda 2);IFNL2; IL-28A; IFN-lambda-2; interferon lambda 2; interferon-lambda 2; Interleukin-28A; Interferon lambda-2; IFN-lambda-2; ZCYTO20; Cytokine ZCYTO20 |
| Gene ID : | 282616 |
| mRNA Refseq : | NM_172138 |
| Protein Refseq : | NP_742150 |
| MIM : | 607401 |
| UniProt ID : | Q8IZJ0 |
| Chromosome Location : | 19q13.13 |
| Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway |
| Function : | Cytokine activity |
Products Types
| ◆ Lysates | ||
| IL28A-5229HCL | Recombinant Human IL28A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionIt can enhance the body's immunity to pathogens by activating the immune system.
IL28A regulates the activity and differentiation of immune cells and enhances the function of the immune system.
It has a long half-life and low clearance, which can maintain a stable plasma concentration.
IL28A is undergoing several clinical trials and is currently showing some efficacy.
This protein is usually synthesized using recombinant DNA technology and purified by column chromatography and other methods.
IL28A can regulate immune response and enhance anti-tumor immunity in tumor therapy.
Customer Reviews (3)
Write a reviewUse cell experiments to verify the regulatory effects on cell signal transduction pathways, such as immune response, inflammation, etc. -
Its molecular weight and composition were determined by western blotting and mass spectrometry, and its biological activity against specific cell lines, such as antiviral effect, was tested. -
Its stability at different temperatures and pH conditions needs to be tested to determine its performance during storage and use. -
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