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Active Recombinant Human Interleukin 28A

Cat.No. : IL28A-539H
Product Overview : Recombinant human IL28A was expressed in E. coli and purified by using conventional chromatography techniques.
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Cat. No. : IL28A-539H
Description : IFN-lambda-1, -2, and -3 (also known as IL29, IL28A and IL28B respectively) are distantly related to the IL10 family and Interferons. All three IFN-lambdas uses a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons.
Source : Human
Host : E.coli
Form : Supplied as a lyophilized powder.
Purity : >98% pure by SDS PAGE and HPLC
Sequence : Region of IFN Gamma 2 protein corresponding to amino acids PVARLHGALP DARGCHIAQF KSLSPQELQA FKRAKDALEE SLLLKDCRCH SRLFPRTWDL RQLQVRERPM ALEAELALTL KVLEATADTD PALVDVLDQP LHTLHHILSQ FRACIQPQPT AGPRTRGRLH HWLYRLQEAP KKESPGCLEA SVTFNLFRLL TRDLNCVASG DLCV.
Molecular Mass : 19.6 kDa
Applications : Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions
Endotoxin Levels : Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Bioactivity : Determined by its ability to activate STAT following receptor-ligand interaction.
Storage : Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
Tag : Non
Gene Name : IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens ]
Official Symbol : IL28A
Synonyms : IL28A; interleukin 28A (interferon, lambda 2);IFNL2; IL-28A; IFN-lambda-2; interferon lambda 2; interferon-lambda 2; Interleukin-28A; Interferon lambda-2; IFN-lambda-2; ZCYTO20; Cytokine ZCYTO20
Gene ID : 282616
mRNA Refseq : NM_172138
Protein Refseq : NP_742150
MIM : 607401
UniProt ID : Q8IZJ0
Chromosome Location : 19q13.13
Pathway : Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway
Function : Cytokine activity

Not For Human Consumption!

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Customer Reviews (3)

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Reviews
11/15/2022

    No need to prepare a special environment, storage conditions are very simple, can be stored for a long time.

    10/04/2020

      Very stable, strong anti-pollution ability, the experimental results are very good.

      07/16/2019

        The labeling effect is very good, and fluorescent labeling can be carried out.

        Q&As (6)

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        What is the main mechanism of action of IL28A? 05/24/2021

        It can enhance the body's immunity to pathogens by activating the immune system.

        What is the role IL28A on the immune system? 03/11/2021

        IL28A regulates the activity and differentiation of immune cells and enhances the function of the immune system.

        What are the pharmacokinetic characteristics of IL28A? 03/09/2021

        It has a long half-life and low clearance, which can maintain a stable plasma concentration.

        How's the progress of clinical trials of IL28A? 06/20/2020

        IL28A is undergoing several clinical trials and is currently showing some efficacy.

        How the synthesis and purification method of IL28A? 06/19/2020

        This protein is usually synthesized using recombinant DNA technology and purified by column chromatography and other methods.

        What are the application prospects of IL28A in tumor therapy? 08/10/2019

        IL28A can regulate immune response and enhance anti-tumor immunity in tumor therapy.

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