Recombinant Human IL3RA Protein, C-Fc-Avi tagged, Biotinylated
|Product Overview :
|Biotinylated Recombinant Human Interleukin-3 Receptor Subunit Alpha is produced by our Mammalian expression system and the target gene encoding Thr19-Arg305 is expressed with a Fc, Avi tag at the C-terminus.
- Gene Information
- Related Products
|CD123, also known as Interleukin-3 receptor subunit alpha, belongs to the type I cytokine receptor family. In mouse, there are two classes of high-affinity IL3 receptors. One contains an IL3-specific beta subunit and the other contains the beta subunit also shared by high-affinity IL5 and GM-CSF receptors. CD123 stimulates the proliferation and differentiation of hemopoietic cells including the pluripotent hematopoietic stem cells as well as various lineage?committed cells. CD123 is a heterodimer consisting of an alpha and a beta subunit. The alpha subunit alone binds IL?3 with low affinity. The beta subunit does not bind IL-3 by itself but is required for the high-affinity binding of IL-3 to the heterodimeric receptor complex.
|Protein Length :
|Less than 0.1 ng/μg (1 EU/μg)
|Storage Buffer :
|Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
|Gene Name :
|IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens (human) ]
|Official Symbol :
|Interleukin-3 receptor subunit alpha; IL-3 receptor subunit alpha; IL-3R subunitalpha; IL-3R-alpha; IL-3RA; CD123
|Gene ID :
|mRNA Refseq :
|Protein Refseq :
|UniProt ID :
|◆ Recombinant Protein
|Recombinant Human IL3RA Protein (Met1-Arg305), HlgG1 Fc-tagged
|Recombinant Mouse IL3RA Protein, His (Fc)-Avi-tagged
|Recombinant Human IL3RA Protein (ECD), His-tagged(C-ter)
|Active Recombinant Human IL3RA Protein, His/Flag/StrepII-tagged
|Recombinant Human IL3RA Protein, His (Fc)-Avi-tagged
|Recombinant Human IL3RA cell lysate
|Recombinant Canine IL3RA cell lysate
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
The feasibility of personalized therapy depends on the specific disease type and patient situation, and more research is needed to determine the application of personalized therapy to Il3ra.
Il3ra has certain promise in clinical application, especially in the treatment of immune-related diseases.
Regulates the proliferation and differentiation of immune cells by binding to its interacting cytokine IL-3, and plays a role in regulating the function of the immune system.
Clinical trials of recombinant Il3ra have been conducted in different disease areas. At present, some early trials show its potential in the treatment of certain diseases, but more research is needed to verify its efficacy and safety.
The Il3ra can regulate the proliferation and differentiation of different types of immune cells in the immune system, thus affecting the function of the immune system.
Il3ra is generally well tolerated, but some minor side effects such as headache and nausea may occur. Serious side effects are rare.
Customer Reviews (3)Write a review
In special environment, good stability.
Good crystallization property and good effect.
Has the expected biological activity, such as enzyme activity and receptor binding activity, and so on.
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