Recombinant Human IL3RA Protein, Fc/His-tagged, FITC conjugated
| Cat.No. : | IL3RA-3248HF |
| Product Overview : | FITC conjugated recombinant human IL3RA (NP_002174.1) extracellular domain (Met 1-Arg 305), fused with the polyhistidine-tagged Fc region of human IgG1 at the C-terminus, was produced in Human Cell. |
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| Source : | HEK293 |
| Species : | Human |
| Tag : | Fc/His |
| Form : | Lyophilized |
| Molecular Mass : | The recombinant human IL3RA/Fc is a disulfide-linked homodimer. The reduced monomer comprises 535 amino acids and has a predicted molecular mass of 61 kDa. As a result of glycosylation, the apparent molecular mass of rh IL3RA/Fc monomer is approximately 80-90 kDa in SDS-PAGE under reducing conditions. |
| Protein length : | 535 |
| Endotoxin : | < 1.0 EU/ μg of the protein as determined by the LAL method. |
| Characteristic : | Disulfide-linked homodimer Labeled with FITC via amines Excitation source: 488 nm spectral line, argon-ion laser Excitation Wavelength: 488 nm Emission Wavelength: 535 nm |
| Stability : | Samples are stable for up to 12 months from date of receipt at -70 centigrade. |
| Storage : | Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Storage Buffer : | Lyophilized from sterile PBS, pH 7.4 |
| Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
| Gene Name : | IL3RA interleukin 3 receptor, alpha (low affinity) [ Homo sapiens ] |
| Official Symbol : | IL3RA |
| Gene ID : | 3563 |
| mRNA Refseq : | NM_002183 |
| Protein Refseq : | NP_002174 |
| MIM : | 308385 |
| UniProt ID : | P26951 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe feasibility of personalized therapy depends on the specific disease type and patient situation, and more research is needed to determine the application of personalized therapy to Il3ra.
Il3ra has certain promise in clinical application, especially in the treatment of immune-related diseases.
Regulates the proliferation and differentiation of immune cells by binding to its interacting cytokine IL-3, and plays a role in regulating the function of the immune system.
Clinical trials of recombinant Il3ra have been conducted in different disease areas. At present, some early trials show its potential in the treatment of certain diseases, but more research is needed to verify its efficacy and safety.
The Il3ra can regulate the proliferation and differentiation of different types of immune cells in the immune system, thus affecting the function of the immune system.
Il3ra is generally well tolerated, but some minor side effects such as headache and nausea may occur. Serious side effects are rare.
Customer Reviews (3)
Write a reviewIt is highly specific, that is, it binds only to its receptor IL-3R, and it has high potential in fighting disease and drug discovery -
Depending on the need, different IL-3Rα variants or mutants can be customized through techniques such as genetic modification to achieve the production of their specific properties. -
IL-3rα, by binding to its receptor, plays an important role in regulating biological processes such as cell proliferation and differentiation, and its biological activity needs to be guaranteed and can be detected by biological identification and other methods. -
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