CD123 is a 70 kD alpha chain subunit of the IL-3 receptor (IL-3R alpha). It is a member of the immunoglobulin superfamily that is expressed on hematopoietic progenitors, basophils, mast cells, and megakaryocytes. This transmembrane glycoprotein can bind I
IL3RA involved in several pathways and played different roles in them. We selected most pathways IL3RA participated on our site, such as Cytokine-cytokine receptor interaction, PIK-Akt signaling pathway, Apoptosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL3RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
IL3RA has several biochemical functions, for example, interleukin-3 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL3RA itself. We selected most functions IL3RA had, and list some proteins which have the same functions with IL3RA. You can find most of the proteins on our site.
interleukin-3 receptor activity
IL3RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL3RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL3RA.
The feasibility of personalized therapy depends on the specific disease type and patient situation, and more research is needed to determine the application of personalized therapy to Il3ra.
Does Il3ra have clinical application prospects? What are the prospects?
Il3ra has certain promise in clinical application, especially in the treatment of immune-related diseases.
What is the action mechanism of Il3ra?
Regulates the proliferation and differentiation of immune cells by binding to its interacting cytokine IL-3, and plays a role in regulating the function of the immune system.
How is the clinical trial of Il3ra progressing?
Clinical trials of recombinant Il3ra have been conducted in different disease areas. At present, some early trials show its potential in the treatment of certain diseases, but more research is needed to verify its efficacy and safety.
What is the specific effect of Il3ra on the immune system?
The Il3ra can regulate the proliferation and differentiation of different types of immune cells in the immune system, thus affecting the function of the immune system.
Does Il3ra have side effects?
Il3ra is generally well tolerated, but some minor side effects such as headache and nausea may occur. Serious side effects are rare.