IL3RA

  • Official Full Name

    interleukin 3 receptor, alpha (low affinity)

  • Overview

    CD123 is a 70 kD alpha chain subunit of the IL-3 receptor (IL-3R alpha). It is a member of the immunoglobulin superfamily that is expressed on hematopoietic progenitors, basophils, mast cells, and megakaryocytes. This transmembrane glycoprotein can bind I
  • Synonyms

    IL3RA; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; CD123; IL-3RA; IL-3R-alpha; CD123 antigen; IL-3R subunit alpha; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; IL3R; IL3RX; IL3RY; IL3RAY; hIL-3Ra; MGC34174;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chromatography Reagents
  • Canine
  • Cynomolgus
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rhesus monkey
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Human cells
  • Human Cells
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf21 Insect Cell
  • Spodoptera Frugiperda
  • Spodopterafrugiperda
  • Wheat Germ
  • C
  • Fc
  • Avi
  • hFc
  • 6×His
  • His
  • DYKDDDDK
  • Fc\Avi
  • Fc|His
  • Flag
  • GST
  • HIgG
  • hIgG1
  • hIgG4
  • His (Fc)
  • His(C
  • ter)
  • His|Flag|StrepII
  • HlgG1 Fc
  • lFc
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IL3RA-121H Active Recombinant Human IL3RA protein, Fc-tagged HEK293 Fc
Human IL3RA-29795TH Recombinant Human IL3RA, Fc-tagged Fc
Human IL3RA-430H Recombinant Human IL3RA, His-Flag-StrepII-tagged HEK293 His/Flag/StrepII
Human IL3RA-3248H Recombinant Human IL3RA, Fc-His tagged Human Cell Fc/His
Human IL3RA-3178H Recombinant Human IL3RA, His tagged Human Cell His
Human IL3RA-420H Recombinant Human IL3RA, MYC/DDK-tagged HEK293 Myc/DDK
Human IL3RA-1644H Recombinant Human Interleukin 3 Receptor, Alpha (Low Affinity) Mammalian cells N/A
Human IL3RA-440H Recombinant Human IL3RA Wheat Germ N/A
Human IL3RA-109H Recombinant Human IL3RA protein, T7/His-tagged E.coli T7/His
Human IL3RA-450H Recombinant Human IL3RA, GST-tagged Wheat Germ GST
Human IL3RA-2433HCL Recombinant Human IL3RA cell lysate Human Cell N/A
Human IL3RA-121HA Recombinant Human IL3RA protein, Fc-tagged, APC labeled HEK293 Fc
Human IL3RA-327H Active Recombinant Human IL3RA protein, lFc-tagged HEK293 lFc
Human IL3RA-2053H Active Recombinant Human IL3RA protein, His-tagged HEK293 His
Human IL3RA-5184H Active Recombinant Human IL3RA Protein, His/Flag/StrepII-tagged Human cells His/Flag/StrepII
Human IL3RA-29795THA Recombinant Human IL3RA protein, Fc-tagged, APC labeled HEK293 Fc
Human IL3RA-151H Recombinant Human IL3RA Protein, DYKDDDDK-tagged Human Cells DYKDDDDK
Human IL3RA-6326H Recombinant Human IL3RA Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human IL3RA-121HAF555 Recombinant Human IL3RA Protein, hFc-tagged, Alexa Fluor 555 conjugated HEK293 hFc
Human IL3RA-1120H Recombinant Human IL3RA Protein (Met1-Arg305), HlgG1 Fc-tagged HEK293 HlgG1 Fc
Human IL3RA-157H Recombinant Human IL3RA(Thr19-Arg305) Protein, C-Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi
Human IL3RA-121HAF488 Recombinant Human IL3RA Protein, hFc-tagged, Alexa Fluor 488 conjugated HEK293 hFc
Human IL3RA-3248HAF555 Recombinant Human IL3RA Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His
Human IL3RA-3248HAF488 Recombinant Human IL3RA Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His
Human IL3RA-121HF Recombinant Human IL3RA Protein, hFc-tagged, FITC conjugated HEK293 hFc
Human IL3RA-29795THAF488 Recombinant Human IL3RA Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
Human IL3RA-29795THAF647 Recombinant Human IL3RA Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
Human IL3RA-29795THAF555 Recombinant Human IL3RA Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
Human IL3RA-202H Recombinant Human IL3RA Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter)
Human IL3RA-702HFL Recombinant Full Length Human IL3RA Protein, C-Flag-tagged Mammalian cells Flag
Human IL3RA-29795THF Recombinant Human IL3RA Protein, Fc-tagged, FITC conjugated HEK293 Fc
Human IL3RA-121HAF647 Recombinant Human IL3RA Protein, hFc-tagged, Alexa Fluor 647 conjugated HEK293 hFc
Human IL3RA-1176H Recombinant Human IL3RA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human IL3RA-2652H Active Recombinant Human IL3RA protein, His-tagged HEK293 His
Human IL3RA-29795THP Recombinant Human IL3RA protein, Fc-tagged, R-PE labeled HEK293 Fc
Human IL3RA-3248HAF647 Recombinant Human IL3RA Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His
Human IL3RA-0210H Active Recombinant Human IL3RA protein, Fc-tagged, FITC-Labeled HEK293 Fc
Human IL3RA-4678H Active Recombinant Human IL3RA Protein, His-tagged, PE-Labeled HEK293 His
Human IL3RA-156H Recombinant Human IL3RA Protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
Human IL3RA-3248HF Recombinant Human IL3RA Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His
Human IL3RA-121HP Recombinant Human IL3RA protein, Fc-tagged, R-PE labeled HEK293 Fc
Human IL3RA-1007HF Recombinant Full Length Human IL3RA Protein In Vitro Cell Free System
Human IL3RA-178H Recombinant Human IL3RA Protein, Fc\Avi-tagged Human Cell Fc\Avi
Human IL3RA-06H Recombinant Human IL3RA Protein, C-Fc-Avi tagged, Biotinylated Human Cell C-Fc-Avi
Human IL3RA-3248HP Recombinant Human IL3RA protein, Fc-His-tagged, R-PE labeled HEK293 Fc/His
Human IL3RA-556H Recombinant Human IL3RA Protein (Thr19-Arg305), C-hFc and 6×His-tagged HEK293 C-hFc and 6×His
Human IL3RA-1176H-B Recombinant Human IL3RA Protein Pre-coupled Magnetic Beads HEK293
Human IL3RA-3248HA Recombinant Human IL3RA protein, Fc-His-tagged, APC labeled HEK293 Fc/His
Human IL3RA-4278H Recombinant Human IL3RA Protein (Met1-Arg305), C-His tagged Mammalian cells C-His
Human IL3RA-0212H Recombinant Human IL3RA protein, His-tagged, FITC-Labeled HEK293 His
Human IL3RA-392M IL3RA protein-coupled magnetic MicroBeads
Mouse Il3ra-5661M Active Recombinant Mouse Interleukin 3 Receptor, Alpha Chain, Fc-tagged Spodoptera Frugiperda Fc
Mouse Il3ra-5661MAF488 Active Recombinant Mouse Il3ra Protein, Fc-tagged, Alexa Fluor 488 conjugated Insect Cell Fc
Mouse Il3ra-5661MAF555 Active Recombinant Mouse Il3ra Protein, Fc-tagged, Alexa Fluor 555 conjugated Insect Cell Fc
Mouse Il3ra-5661MF Active Recombinant Mouse Il3ra Protein, Fc-tagged, FITC conjugated Insect Cell Fc
Mouse Il3ra-5661MAF647 Active Recombinant Mouse Il3ra Protein, Fc-tagged, Alexa Fluor 647 conjugated Insect Cell Fc
Mouse Il3ra-1755M Recombinant Mouse Interleukin 3 Receptor, Alpha Chain Sf21 Insect Cell N/A
Mouse Il3ra-8312M Recombinant Mouse Il3ra Sf21 Insect Cell N/A
Mouse IL3RA-8171M Recombinant Mouse IL3RA Protein Mammalian Cell His
Mouse Il3ra-918M Recombinant Mouse Il3ra Protein, Fc-tagged HEK293 Fc
Mouse Il3ra-919M Active Recombinant Mouse Il3ra protein, His-tagged HEK293 His
Mouse Il3ra-7059M Recombinant Mouse Il3ra protein, His-tagged E.coli His
Mouse Il3ra-7058M Recombinant Mouse Il3ra protein, His-tagged E.coli His
Mouse Il3ra-918MAF488 Recombinant Mouse Il3ra Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc
Mouse Il3ra-5661MA Recombinant Mouse Il3ra protein, Fc-tagged, APC labeled Spodopterafrugiperda Fc
Mouse Il3ra-918MAF555 Recombinant Mouse Il3ra Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc
Mouse IL3RA-4517M Recombinant Mouse IL3RA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Il3ra-5661MP Recombinant Mouse Il3ra protein, Fc-tagged, R-PE labeled Spodopterafrugiperda Fc
Mouse Il3ra-918MA Recombinant Mouse Il3ra protein, Fc-tagged, APC labeled HEK293 Fc
Mouse Il3ra-918MAF647 Recombinant Mouse Il3ra Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc
Mouse Il3ra-918MP Recombinant Mouse Il3ra protein, Fc-tagged, R-PE labeled HEK293 Fc
Mouse Il3ra-918MF Recombinant Mouse Il3ra Protein, Fc-tagged, FITC conjugated HEK293 Fc
Mouse IL3RA-03M Recombinant Mouse IL3RA Protein, hIgG-His-tagged Insect Cell HIgG/His
Mouse IL3RA-4517M-B Recombinant Mouse IL3RA Protein Pre-coupled Magnetic Beads HEK293
Rhesus monkey IL3RA-1558R Recombinant Rhesus Monkey IL3RA Protein, hIgG4-tagged HEK293 hIgG4
Rhesus monkey IL3RA-1557R Recombinant Rhesus Monkey IL3RA Protein, hIgG1-tagged HEK293 hIgG1
Rhesus monkey IL3RA-1556R Recombinant Rhesus Monkey IL3RA Protein HEK293 N/A
Canine IL3RA-177C Recombinant Canine IL3RA protein, His-tagged HEK293 His
Canine IL3RA-742CCL Recombinant Canine IL3RA cell lysate Human Cell N/A
Canine IL3RA-0211C Recombinant Canine IL3RA protein, His-tagged HEK293 His
Cynomolgus IL3RA-179C Recombinant Cynomolgus IL3RA(Arg18-Arg302) Protein, C-6*His-tagged HEK293 His
Cynomolgus Monkey IL3RA-1578C Recombinant Cynomolgus Monkey IL3RA Protein, hIgG1-tagged HEK293 hFc
Homo sapiens (Human) RFL6212HF Recombinant Full Length Human Interleukin-3 Receptor Subunit Alpha(Il3Ra) Protein, His-Tagged E.coli expression system His
Mus musculus (Mouse) RFL34156MF Recombinant Full Length Mouse Interleukin-3 Receptor Subunit Alpha(Il3Ra) Protein, His-Tagged E.coli expression system His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IL3RA Related Gene Family
  • IL3RA Related Research Area
  • IL3RA Related Signal Pathway

IL3RA involved in several pathways and played different roles in them. We selected most pathways IL3RA participated on our site, such as Cytokine-cytokine receptor interaction, PIK-Akt signaling pathway, Apoptosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL3RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIFNA14;GH2;VEGFC;IL1A;CXCL13;ACVR1;CD70;CXCL10;TNFSF12
PIK-Akt signaling pathwayITGB5;PKN3;LAMA5;MTOR;PIK3CG;FGF20;ITGA9;COL6A4;IFNA4
ApoptosisPRKACG;IRAK2;ADD1;NMT1;PPP3CCB;MAP3K14;NFKBIA;XIAP;FAS
Jak-STAT signaling pathwaySOCS7;IFNG1-2;LEPB;PTPN11A;IL10RA;Il23a;STAT6;IL22;STAT5A
Hematopoietic cell lineageMME;GM13305;ITGA1;IL1B;IL3RA;ITGA6;THPO;IL1A;Kitl

IL3RA has several biochemical functions, for example, interleukin-3 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL3RA itself. We selected most functions IL3RA had, and list some proteins which have the same functions with IL3RA. You can find most of the proteins on our site.

Function Related Protein
interleukin-3 receptor activity

IL3RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL3RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL3RA.

FYN; NCK1; PLCG1; GRB2; CDK1; CDC25A; GNA12; NR0B2; LNX1; FOXP1; SGK2; SAE1

IL
  • Q&As
  • Reviews

Q&As (6)

Ask a question
Can Il3ra be personalized? 08/01/2022

The feasibility of personalized therapy depends on the specific disease type and patient situation, and more research is needed to determine the application of personalized therapy to Il3ra.

Does Il3ra have clinical application prospects? What are the prospects? 05/19/2022

Il3ra has certain promise in clinical application, especially in the treatment of immune-related diseases.

What is the action mechanism of Il3ra? 04/24/2022

Regulates the proliferation and differentiation of immune cells by binding to its interacting cytokine IL-3, and plays a role in regulating the function of the immune system.

How is the clinical trial of Il3ra progressing? 09/16/2020

Clinical trials of recombinant Il3ra have been conducted in different disease areas. At present, some early trials show its potential in the treatment of certain diseases, but more research is needed to verify its efficacy and safety.

What is the specific effect of Il3ra on the immune system? 08/06/2019

The Il3ra can regulate the proliferation and differentiation of different types of immune cells in the immune system, thus affecting the function of the immune system.

Does Il3ra have side effects? 05/24/2019

Il3ra is generally well tolerated, but some minor side effects such as headache and nausea may occur. Serious side effects are rare.

Customer Reviews (3)

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Reviews
07/24/2022

    In special environment, good stability.

    05/25/2022

      Good crystallization property and good effect.

      06/29/2021

        Has the expected biological activity, such as enzyme activity and receptor binding activity, and so on.

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