|Official Full Name||interleukin 3 receptor, alpha (low affinity)|
|Background||CD123 is a 70 kD alpha chain subunit of the IL-3 receptor (IL-3R alpha). It is a member of the immunoglobulin superfamily that is expressed on hematopoietic progenitors, basophils, mast cells, and megakaryocytes. This transmembrane glycoprotein can bind I|
|Synonyms||IL3RA; interleukin 3 receptor, alpha (low affinity); interleukin-3 receptor subunit alpha; CD123; IL-3RA; IL-3R-alpha; CD123 antigen; IL-3R subunit alpha; IL-3 receptor subunit alpha; IL-3 receptor alpha SP2 isoform; IL3R; IL3RX; IL3RY; IL3RAY; hIL-3Ra; MGC34174|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
IL3RA involved in several pathways and played different roles in them. We selected most pathways IL3RA participated on our site, such as Cytokine-cytokine receptor interaction, PIK-Akt signaling pathway, Apoptosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL3RA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cytokine-cytokine receptor interaction||IL7R; IFNA12; IFNA4; IL22RA2; IL3; VEGFC; KITA; KITLGB; Il23a; MET|
|PIK-Akt signaling pathway||PIK3CA; IFNA4; CCNE1; PCK1; FGF12; EIF4E1B; RXRA; FIGF; DDIT4; IL2RG|
|Apoptosis||RELA; TNFRSF10B; CFLAR; PPP3CC; HIST1H1B; NFKBIA; VIML; CAPN1; DYNLL2; CASP6L1|
|Jak-STAT signaling pathway||GHR; Ifna11; IFNA7; CCND1; PIK3CG; CISHB; CRFB16; IL21R.1; MCL1A; STAT4|
|Hematopoietic cell lineage||IL11RA2; MME; HLA-DRB4; GM-CSF; CSF3R; CD1C; ANPEP; CD1D2; CD1A; CSF1|
IL3RA has several biochemical functions, for example, interleukin-3 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL3RA itself. We selected most functions IL3RA had, and list some proteins which have the same functions with IL3RA. You can find most of the proteins on our site.
|interleukin-3 receptor activity||IL3RA|
IL3RA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL3RA here. Most of them are supplied by our site. Hope this information will be useful for your research of IL3RA.
FYN; NCK1; PLCG1; GRB2; CDK1; CDC25A; GNA12; NR0B2; LNX1; FOXP1; SGK2; SAE1