Recombinant Human Interleukin 28A (Interferon, Lambda 2), His-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
Cat.No. : | IL28A-221H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human interleukin 28A DNA sequence encoding the signal peptide from human CD33 was fused to the carboxylterminally his-tagged mature human IL-29 (Gly 20 - Thr 200) was expressed ina mouse NSO Cells. |
Description : | Interleukin-28A (IL-28A) also known as IFNL2 is a novel cytokine that exerts its biological effects through a receptor that also binds IL28B and IL29. IL28A induces phosphorylation of STAT1, STAT2, and STAT3. IL-28A has antiviral activities and stimulates antiviral responses through a heterodimeric receptor. IL-28A represents a potential novel approach for therapy of Th1-mediated inflammatory diseases such as T-cell-mediated hepatitis. |
Source : | Mammalian cells |
Molecular Weight : | The predicted molecular weight of Recombinant Human IL-28A is Mr 20.8 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 24 kDa. |
State Of Matter : | Lyophilized. |
Formulation : | This recombinant protein was 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 – 7.3 with no calcium, magnesium, or preservatives. |
Purity : | > 97% by SDS Page and analyzed by silver stain. |
Endotoxin : | < 1.0 EU/µg as determined by the LAL method. |
Biological Activity : | The biological activity of Human IFN-λ2 was determined by in an anti-viral assay using human HepG2 cells infected with encephalomyocarditis virus. The expected ED50 for this effect is typically 1 - 5 ng/mL. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions. |
Gene Name : | IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens ] |
Synonyms : | IL28A; interleukin 28A (interferon, lambda 2);IFNL2; IL-28A; IFN-lambda-2; interferon lambda 2; interferon-lambda 2; Interleukin-28A; Interferon lambda-2; IFN-lambda-2; ZCYTO20; Cytokine ZCYTO20 |
Gene ID : | 282616 |
mRNA Refseq : | NM_172138 |
Protein Refseq : | NP_742150 |
UniProt ID : | Q8IZJ0 |
Chromosome Location : | 19q13.13 |
MIM : | 607401 |
Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway |
Function : | Cytokine activity |
◆ Recombinant Protein
IL28A-33H | Recombinant Human IL28A Protein, Animal Free | +Inquiry |
Il28a-5202M | Recombinant Mouse Il28a Protein | +Inquiry |
IL28A-4511M | Recombinant Mouse IL28A Protein, His (Fc)-Avi-tagged | +Inquiry |
IL28A-3150H | Recombinant Human IL28A Protein, His (Fc)-Avi-tagged | +Inquiry |
Il28a-10585M | Recombinant Mouse Il28a Protein, His (Fc)-Avi-tagged | +Inquiry |
|
◆ Lysates
IL28A-5229HCL | Recombinant Human IL28A 293 Cell Lysate | +Inquiry |
|
IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
Easy access to products and services you need from our library via powerful searching tools.
Copyright © 2023 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy