Active Recombinant Mouse Il28a Protein
Cat.No. : | Il28a-5202M |
Product Overview : | Mouse Il28a (Q4VK74) partial recombinant protein expressed in Escherichia coli. |
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Description : | Interleukin-28 (IL-28) is a cytokine that comes in two isoforms, IL-28A and IL-28B, and plays a role in immune defense against viruses, including the induction of an "antiviral state" by turning on Mx proteins, 2',5'-oligoadenylate synthetase as well as ISGF3G (Interferon Stimulated Gene Factor 3). IL-28A and IL-28B belong to the type III interferon family of cytokines and are highly similar (in amino acid sequence) to IL-29. Their classification as Interferons is due to their ability to induce an antiviral state, while their additional classification as cytokines is due to their chromosomal location as well as the fact that they are encoded by multiple exons, as opposed to a single exon, as most type-I IFNs are. |
Source : | E. coli |
Species : | Mouse |
Form : | Lyophilized |
Bio-activity : | Determined by its ability to activate STAT following receptor-ligand interaction. |
Molecular Mass : | 25.0 kDa |
AA Sequence : | MDPVPRATRLPVEAKDCHIAQFKSL SPKELQAFKKAKDAIEKRLLEKDMR CSSHLISRAWDLKQLQVQERPKALQ AEVALTLKVWENMTDSALATILGQP LHTLSHIHSQLQTCTQLQATAEPKP PSRRLSRWLHRLQEAQSKETPGCLE DSVTSNLFRLLTRDLKCVASGDQCV |
Endotoxin : | Endotoxin level is < 0.1 ng/μg (< 1 EU/μg). |
Purity : | 98% |
Applications : | Functional Study SDS-PAGE |
Usage : | Activity assay SDS-PAGE The optimal working dilution should be determined by the end user. |
Storage : | Store at -20 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | Lyophilized from solutions contain no sodiun azide nor carrier protein |
Tag : | Non |
Gene Name : | Il28a interleukin 28A [ Mus musculus ] |
Official Symbol : | Il28a |
Synonyms : | IL28A; interleukin 28A; interleukin-28A; IFN-lambda2; IFN-lambda-2; interferon-lambda2; interferon lambda-2; Ifnl2; IL-28A; EG330496; |
Gene ID : | 330496 |
mRNA Refseq : | NM_001024673 |
Protein Refseq : | NP_001019844 |
Products Types
◆ Lysates | ||
IL28A-5229HCL | Recombinant Human IL28A 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewNo need to prepare a special environment, storage conditions are very simple, can be stored for a long time.
Very stable, strong anti-pollution ability, the experimental results are very good.
The labeling effect is very good, and fluorescent labeling can be carried out.
Q&As (6)
Ask a questionIt can enhance the body's immunity to pathogens by activating the immune system.
IL28A regulates the activity and differentiation of immune cells and enhances the function of the immune system.
It has a long half-life and low clearance, which can maintain a stable plasma concentration.
IL28A is undergoing several clinical trials and is currently showing some efficacy.
This protein is usually synthesized using recombinant DNA technology and purified by column chromatography and other methods.
IL28A can regulate immune response and enhance anti-tumor immunity in tumor therapy.
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