Recombinant Human Mitogen-activated Protein Kinase 8, His-tagged

• Cat.No.: MAPK8-612H
• Product Overview: Recombinant Human full length JNK1ß2 (MAPK8) produced ininsect cellsis fused to an N-terminal His-tag, 48 kDa.

Specification

• Cat. No.: MAPK8-612H
• Description: JNK1 is the major c-Jun kinase after stimulation by inflammatory cytokines and environmental stresses. JNK phosphorylates nuclear receptors c-Jun, ATF-2, p53, Elk- and NFAT1.
• Source: insect cells.
• Long Term Storage: -80°C.

Gene Information

• Gene Name: MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ]
• Synonyms: mitogen-activated protein kinase 8; JNK; JNK1; PRKM8; SAPK1; JNK1A2; JNK21B1/2; MAPK8; JNK-46; MAPK 8; MAP kinase 8; protein kinase JNK1; JUN N-terminal kinase; JNK1 beta protein kinase; JNK1 alpha protein kinase; c-Jun N-terminal kinase 1; stress-activated protein kinase 1; stress-activated protein kinase JNK1; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8 isoform JNK1 alpha1; Stress-activated protein kinase JNK1; OTTHUMP00000019552; EC 2.7.11.24
• Gene ID: 5599
• mRNA Refseq: NM_002750
• Protein Refseq: NP_002741
• MIM: 601158
• UniProt ID: P45983
• Chromosome Location: 10q11.22
• Pathway: Adipocytokine signaling pathway; Colorectal cancer; Epithelial cell signaling in Helicobacter pylori infection; ErbB signaling pathway; Fc epsilon RI signaling pathway; Focal adhesion; GnRH signaling pathway; Insulin signaling pathway; MAPK signaling pathway; NOD-like receptor signaling pathway; Neurotrophin signaling pathway; Pancreatic cancer; Pathways in cancer; Progesterone-mediated oocyte maturation; RIG-I-like receptor signaling pathway; Toll-like receptor signaling pathway; Type II diabetes mellitus; Wnt signaling pathway
• Function: ATP binding; JUN kinase activity; MAP kinase activity; kinase activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity