Recombinant Human Mitogen-activated Protein Kinase 8

Cat.No. : MAPK8-751H
Product Overview : Recombinant Human Human Mitogen-activated Protein Kinase 8 Amino acidsM1-Q384, is expressed inE.coli.
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  • Gene Information
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Cat. No. : MAPK8-751H
Description : Mitogen-activated protein kinase 8 is an enzyme that in humans is encoded by the MAPK8 gene. The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development.
Source : E.coli.
Purification : Immobilized Metal Affinity Chromatography.
Product Identity : JNK1 was confirmed as JNK1 by mass spectroscopy LC-ESI-MS/MS.
MW : 44,292 Da.
Storage Buffer : 50 mM Tris-HCl, pH 7.5; 100 mM NaCl, 5 mM DTT, 20% glycerol.
Concentration : 0.513 μg/μl.
Specific Activity : 2514 pmol/μg×min.
Storage : -80°C. Avoid repeated freeze-thaw cycles!
Gene Name : MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ]
Synonyms :
MAPK8; mitogen-activated protein kinase 8; JNK-46; JNK1 alpha protein kinase; JNK1 beta protein kinase; JUN N-terminal kinase; MAP kinase 8; MAPK 8; OTTHUMP00000019552; c-Jun N-terminal kinase 1; mitogen-activated protein kinase 8 isoform JNK1 alpha1; mitogen-activated protein kinase 8 isoform JNK1 beta2; protein kinase JNK1; stress-activated protein kinase 1; stress-activated protein kinase JNK1; JNK; JNK1; PRKM8; SAPK1; JNK1A2; JNK21B1/2; EC
Gene ID : 5599
mRNA Refseq : NM_002750
Protein Refseq : NP_002741
MIM : 601158
UniProt ID : P45983
Chromosome Location : 10q11.22
Pathway : Colorectal cancer; Epithelial cell signaling in Helicobacter pylori infection; ErbB signaling pathway; Focal adhesion; MAPK signaling pathway; NOD-like receptor signaling pathway; Pathways in cancer; Progesterone-mediated oocyte maturation; Type II diabetes mellitus; Wnt signaling pathway
Function : ATP binding;JUN kinase activity; MAP kinase activity; kinase activity; protein serine/threonine kinase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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