Recombinant Human MAPK8 Protein, His (Fc)-Avi-tagged

• Cat.No.: MAPK8-3435H
• Product Overview: Recombinant Human MAPK8 with His (Fc)-Avi tag was expressed and purified

Specification

• Source: HEK293
• Species: Human
• Tag: His&Fc&Avi
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: ≥85% by SDS-PAGE
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ]
• Official Symbol: MAPK8
• Gene ID: 5599
• mRNA Refseq: NM_002750.2
• Protein Refseq: NP_002741.1
• MIM: 601158
• UniProt ID: P45983

Reviews

04/18/2020

I am confident that the MAPK8 protein will unravel crucial insights into molecular mechanisms, greatly enhancing the significance and impact of my scientific investigations.

12/02/2016

By relying on the MAPK8 protein, I can approach my research with unwavering confidence in its quality and the unparalleled support extended by its manufacturer.

02/25/2016

the manufacturer's commitment to providing excellent technical support adds an additional layer of confidence to my choice of the MAPK8 protein.

Q&As

Is MAPK8 involved in inflammatory processes?

Yes, MAPK8 is implicated in regulating inflammation and immune responses, contributing to the pathogenesis of inflammatory diseases like rheumatoid arthritis and inflammatory bowel disease.

Can MAPK8 inhibitors potentially be used in treating Alzheimer's disease?

Research suggests that MAPK8 inhibitors might have therapeutic potential in managing Alzheimer's disease by modulating neuronal responses and reducing neuroinflammation.

How is MAPK8 protein expression assessed in clinical research?

MAPK8 protein expression is often assessed using techniques like immunohistochemistry, western blotting, or quantitative PCR in clinical samples to understand its role in diseases.

How does MAPK8 influence neuronal function and neurodegeneration?

MAPK8 activation is associated with neuronal stress responses and plays a role in neurodegenerative conditions such as Alzheimer's and Parkinson's diseases.

How does MAPK8 influence cellular apoptosis?

MAPK8 signaling pathways can either promote or suppress apoptosis depending on the cellular context and stimuli, making it a potential target for regulating cell death in disease settings.