Recombinant Human Neurotrophin 3 NTF3-044H

Recombinant Human Neurotrophin 3


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Cat.No. : NTF3-044H Optional Service: Optional requirements on this protein
Product Overview : Recombinant human NT-3 was expressed in E. coli and purified by SDS PAGE and HPLC, 13.6 KDa.
Description : NT-3 is a neurotrophic factor structurally related to beta-NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, Mouse and rat NT-3 are identical.
Source : Human
Host : E.coli
Form : Supplied lyophilized with no additives. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Allow to set for at least 30 minutes, mix well.
Purity : > 98% pure by SDS PAGE and HPLC
Molecular Mass : 13.6 kDa
Applications : Numerous applications are possible with this product and should be tested by the end user under their own laboratory conditions
Endotoxin Levels : Endotoxin level is less than 0.1 ng per ug (1 EU/ug).
Bioactivity : The ED50 as determined by the dose-dependent induction of choline acetyl transferase activity in rat basal forebrain primary septal cell cultures was found to be in the range of 20-50 ng/ml.
Storage : Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.
PDBrendering based on 1b8k. :

Gene Name : NTF3 neurotrophin 3 [ Homo sapiens ]
Official Symbol : NTF3
Synonyms : neurotrophin 3; NT3; HDNF; NGF2; NGF-2; MGC129711; NTF3; NT-3; Nerve growth factor 2; Neurotrophic factor
Gene ID : 4908
mRNA Refseq : NM_001102654
Protein Refseq : NP_001096124
MIM : 162660
UniProt ID : P20783
Chromosome Location : 12p13
Pathway : MAPK signaling pathway; Neurotrophic factor-mediated Trk receptor signaling; Neurotrophin signaling pathway; Trk receptor signaling mediated by the MAPK pathway; p75(NTR)-mediated signaling
Function : growth factor activity; nerve growth factor binding; neurotrophin receptor binding; receptor binding
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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