Recombinant Human IL34 Protein, MYC/DDK-tagged, C13 and N15-labeled

• Cat.No.: IL34-053H
• Product Overview: IL34 MS Standard C13 and N15-labeled recombinant protein (NP_689669) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 27.5 kDa
• AA Sequence: MPRGFTWLRYLGIFLGVALGNEPLE MWPLTQNEECTVTGFLRDKLQYRSR LQYMKHYFPINYKISVPYEGVFRIA NVTRLQRAQVSERELRYLWVLVSLS ATESVQDVLLEGHPSWKYLQEVQTL LLNVQQGLTDVEVSPKVESVLSLLN APGPNLKLVRPKALLDNCFRVMELL YCSCCKQSSVLNWQDCEVPSPQSCS PEPSLQYAATQLYPPPPWSPSSPPH STGSVRPVRAQGEGLLPTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: IL34 interleukin 34 [ Homo sapiens (human) ]
• Official Symbol: IL34
• Synonyms: IL34; interleukin 34; C16orf77; IL-34; interleukin-34
• Gene ID: 146433
• mRNA Refseq: NM_152456
• Protein Refseq: NP_689669
• MIM: 612081
• UniProt ID: Q6ZMJ4

Reviews

05/10/2021

IL34 has shown good biocompatibility and safety in related experiments.

01/19/2020

When using IL34 for experiments, the experimental conditions and results are highly repeatable.

10/24/2019

Quality is stable and reliable, with no significant differences between batches.

Q&As

What is the effect of IL34 on tumor prognosis?

There are no clear studies showing the effect of IL34 on tumor prognosis.

What are the advantages of IL34 over other treatments?

Can fight disease by modulating the immune system and may have better efficacy and fewer side effects than other treatments.

What is the mechanism of action of IL34 in the treatment of tumor?

May inhibit tumor growth and metastasis by enhancing immune cells' ability to attack tumor cells.

How is the clinical trial of IL34 progressing?

No large-scale clinical trials have been reported, but some early studies have shown a potential therapeutic effect.

How does IL34 affect the immune system?

Regulate the function of macrophages and dendritic cells and affect the immune response of the immune system.

How to evaluate the efficacy of IL34?

The evaluation of the efficacy of IL34 usually requires a comprehensive evaluation of clinical symptoms, biochemical indicators, imaging and other indicators.