AHSG

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AHSG

Official Full Name alpha-2-HS-glycoprotein
Background Alpha-2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure.
Synonyms AHSG; alpha-2-HS-glycoprotein; AHS; A2HS; HSGA; FETUA; Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A; Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B; PRO2743; OTTHUMP00000210158; OTTHUMP00000210159
    • Species :
    • Bovine
    • Human
    • Mouse
    • Rat
    • Source :
    • Bovine
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Human Cell
    • Human plasma
    • Insect Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human AHSG-160HG GMP Recombinant Human AHSG protein, His-tagged HEK293 His
    Human AHSG-2173H Recombinant Human AHSG Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Ahsg-557M Recombinant Mouse Ahsg Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Ahsg-7155M Recombinant Mouse Ahsg Protein, His-tagged Insect Cell His
    Human AHSG-1001H Human Leucine-rich Alpha-2-glycoprotein 1 human plasma N/A
    Human AHSG-111H Native Human Alpha 2 HS Glycoprotein Human plasma N/A
    Human AHSG-165H Recombinant Human AHSG Protein, His-tagged E.coli His
    Human AHSG-166H Recombinant Human AHSG Protein, His/GST-tagged E.coli His/GST
    Human AHSG-202H Recombinant Human AHSG protein, T7/His-tagged E.coli T7/His
    Human AHSG-2958HCL Recombinant Human AHSG cell lysate Human Cell N/A
    Human AHSG-4356H Recombinant Human Alpha-2-HS-Glycoprotein Human N/A
    Human AHSG-469H Recombinant Human AHSG Protein HEK293 N/A
    Human AHSG-470H Recombinant Human AHSG Protein, GST-tagged Wheat Germ GST
    Human AHSG-565H Recombinant Human alpha-2-HS-glycoprotein, His-tagged E.coli His
    Human AHSG-704H Recombinant Human AHSG, His tagged Human Cell His
    Human AHSG-7710H Recombinant Human AHSG protein, His-tagged HEK293 His
    Mouse Ahsg-167M Recombinant Mouse Ahsg Protein, His-tagged E.coli His
    Mouse AHSG-2957MCL Recombinant Mouse AHSG cell lysate Human Cell N/A
    Mouse Ahsg-674M Recombinant Mouse Ahsg Protein, His-tagged NS0 His
    Mouse Ahsg-705M Recombinant Mouse Ahsg, His tagged Human Cell His
    Mouse Ahsg-92M Recombinant Mouse Ahsg, His-tagged Insect Cell His
    Rat Ahsg-168R Recombinant Rat Ahsg Protein, His-tagged E.coli His
    Rat aHSG-3325R Recombinant Rat aHSG, His-tagged E.coli His
    Rat AHSG-574R Recombinant Rat AHSG Protein Mammalian Cell His
    Bovine AHSG-331BI Immobilized Bovine AHSG protein Bovine N/A

    AHSG involved in several pathways and played different roles in them. We selected most pathways AHSG participated on our site, such as BMP receptor signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with AHSG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    BMP receptor signaling GREM1; FST; CTDSPL; RGMB; SKI; SOSTDC1; CTDSP2; CHRDL1; AHSG; CTDSP1

    AHSG has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity, kinase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AHSG itself. We selected most functions AHSG had, and list some proteins which have the same functions with AHSG. You can find most of the proteins on our site.

    Function Related Protein
    cysteine-type endopeptidase inhibitor activity CST14B.1; CST8; AHSG1; FETUB; SERPINB3; CST2; CARD18; BIRC7; WFDC2; NGP
    endopeptidase inhibitor activity C4A; Cstb; SPINK1; SLPI; CST14B.1; TFPI; PI3; A1i3; RENBP; C3P1
    kinase inhibitor activity LRP6; SOCS1; RHOH; AHSG

    AHSG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AHSG here. Most of them are supplied by our site. Hope this information will be useful for your research of AHSG.

    Hsd17b7; ABL1; Smad3; Mad2l1; AKT1; CDC42; GRB2; d-mannose; ALB; ATF2

    Fernandez-Grijalva, AL; Aguilar-Lemarroy, A; et al. Alpha 2HS-glycoprotein, a tumor-associated antigen (TAA) detected in Mexican patients with early-stage breast cancer. JOURNAL OF PROTEOMICS 112:301-312(2015).
    Biswas, S; Sharma, S; et al. Identification of Novel Autoantigen in the Synovial Fluid of Rheumatoid Arthritis Patients Using an Immunoproteomics Approach. PLOS ONE 8:-(2013).

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