AHSG
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Official Full Name
alpha-2-HS-glycoprotein
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Overview
Alpha-2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. -
Synonyms
AHSG; alpha-2-HS-glycoprotein; AHS; A2HS; HSGA; FETUA; Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A; Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B; PRO2743; OTTHUMP00000210158; OTTHUMP00000210159;
- Recombinant Proteins
- Cell & Tissue Lysates
- GMP Proteins
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Others
- Bovine
- Cattle
- Guinea pig
- Human
- Macaca mulatta (Rhesus macaque)
- Mouse
- Pig
- Rat
- Bovine
- E. coli
- E.coli
- HEK293
- HEK293T
- Human
- Human Cell
- human plasma
- Human plasma
- In Vitro Cell Free System
- Insect Cell
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- Flag
- GST
- His (Fc)
- Avi
- His|GST
- Myc
- DDK
- MYC
- N/A
- N
- T7|His
- Involved Pathway
- Protein Function
- Interacting Protein
- AHSG Related Articles
- AHSG Related Research Area
AHSG involved in several pathways and played different roles in them. We selected most pathways AHSG participated on our site, such as BMP receptor signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with AHSG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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BMP receptor signaling | FST;NOG;CTDSP1;AHSG;RGMA;CTDSPL;GREM1;RGMB;HFE2 |
AHSG has several biochemical functions, for example, cysteine-type endopeptidase inhibitor activity, endopeptidase inhibitor activity, kinase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by AHSG itself. We selected most functions AHSG had, and list some proteins which have the same functions with AHSG. You can find most of the proteins on our site.
Function | Related Protein |
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cysteine-type endopeptidase inhibitor activity | CST14B.1;NAIP1;CST9;CTLA2B;CST2;BIRC5B;FETUB;CSTA;HRG |
endopeptidase inhibitor activity | A2ML;SERPINA1D;CST7;SERPINA1E;MUG2;PSMF1;Cstb;Hc;MUG1 |
kinase inhibitor activity | RHOH;LRP6;AHSG;SOCS1 |
AHSG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with AHSG here. Most of them are supplied by our site. Hope this information will be useful for your research of AHSG.
Hsd17b7; ABL1; Smad3; Mad2l1; AKT1; CDC42; GRB2; d-mannose; ALB; ATF2
- Q&As
- Reviews
Q&As (10)
Ask a questionTechniques like co-immunoprecipitation coupled with mass spectrometry can reveal AHSG's interactome, shedding light on its broader functional networks.
AHSG levels may be altered in these conditions, making it a potential biomarker for disease progression or severity.
AHSG's interaction with insulin and adipokines could impact insulin sensitivity and metabolism, contributing to insulin resistance in conditions like type 2 diabetes.
AHSG can form complexes with fetuin-B and fetuin-A, which have implications for calcium homeostasis, insulin signaling, and other physiological processes.
AHSG can interact with immune cells and cytokines, potentially influencing immune responses. Dysregulated AHSG levels might contribute to autoimmune diseases.
AHSG's interactions with proteins like albumin and hormones can impact its bioavailability and activity, influencing physiological processes.
Techniques such as mass spectrometry, lectin affinity chromatography, and glycan analysis can provide insights into AHSG's glycosylation patterns.
AHSG binds to calcium ions and influences their distribution in the body. Dysregulation may impact bone health and contribute to conditions like osteoporosis.
Techniques such as ion exchange chromatography, gel filtration, and affinity chromatography can be used to isolate and purify AHSG from biological samples.
Genetic polymorphisms in the AHSG gene might lead to altered AHSG levels or structural changes, potentially influencing its physiological roles.
Customer Reviews (5)
Write a reviewAbsolutely loving the lab protein – a real game changer!
Great value for the quality, and the speedy delivery was a pleasant surprise!
Thumbs up for the protein, it's become my new favorite.
Can't help but smile at the results from the product!
Balanced pricing, superior quality, and top-level customer assistance.
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