|Official Full Name||bone morphogenetic protein receptor, type IA|
|Background||The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.|
|Synonyms||BMPR1A; bone morphogenetic protein receptor, type IA; ACVRLK3; bone morphogenetic protein receptor type-1A; ALK3; CD292; ALK-3; BMPR-1A; BMP type-1A receptor; activin receptor-like kinase 3; activin A receptor, type II-like kinase 3; serine/threonine-prot|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
BMPR1A involved in several pathways and played different roles in them. We selected most pathways BMPR1A participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMPR1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cytokine-cytokine receptor interaction||CCR10; IL11; CCL20A.3; BMPR1BB; CXCR4A; OSMR; CCR8L; IL5RA; IL1R2; TNFRSF17|
|TGF-beta signaling pathway||BMP7B; SPAW; CHRD; TGFB1; ROCK2B; NOG; SMAD3; NDR1; RHOAD; NODAL|
|Hippo signaling pathway||PPP1CC; MOB1A; GDF5; BMP5; SMAD1; LLGL1; WNT2; RASSF1; BMP8A; CCND1|
|Signaling pathways regulating pluripotency of stem cells||NEUROG1; WNT9A; FGFR1; FZD9; BMP2; WNT8B; BMPR1A; SMAD2; GRB2; WNT6|
BMPR1A has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by BMPR1A itself. We selected most functions BMPR1A had, and list some proteins which have the same functions with BMPR1A. You can find most of the proteins on our site.
|ATP binding||TSSK6; PANK3; CDC42BPG; GAK; OXSR1; KIFC2; TOR2A; KIF1C; HELZ2; DHX57|
|RNA polymerase II transcription factor activity, sequence-specific DNA binding||ATF4; TFAP2D; JUNBB; ZNF434; BHLHE40; FOXB1A; SOX21; SCAND1; FOXP1; PAX6|
|SMAD binding||PML; RNF111; SNW1; TGFBR3; COL5A2; SKILB; BMP2; ACVRL1; COL1A2; ACVR1|
|glycoprotein binding||F7; LCK; LACRT; DNAJC5; SERPINA1E; ITGAM; EDEM2; LDLR; CANX; SERPINA1D|
|metal ion binding||CASZ1; SPATA21; TATDN3; MAP3K3; ZBTB8A; ZFY1; MIPEP; SP8; SETDB1A; RBM27|
|protein binding||MBL2; LAMTOR3; C10orf46; PRR3; BTRC; TRPC4AP; EHMT2; USP34; HTT; TCTE3|
|protein homodimerization activity||CORO1A; GPD1L; MIXL1; TENM3; HAND1; CPNE1; PAH; FGFR1OP2; BAX; BCL2|
|protein serine/threonine kinase activity||STK24; SMOK2B; DCLK3; TAOK3; CDC42BPA; TESK1; PIK3CG; PLK2B; STK25; TAF1|
|receptor signaling protein serine/threonine kinase activity||PANK1A; OXSR1B; STK25B; ACVR1BA; STK39; BMPR2B; OXSR1A; ACVR1C; STK25A; PAK2B|
|transmembrane receptor protein serine/threonine kinase activity||ACVR1BA; BMPR1BA; BMPR2B; BMPR1A; BMPR1AB; ACVR1; ACVR1L; TGFBR2; TGFBR1A; ACVR2AA|
BMPR1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMPR1A here. Most of them are supplied by our site. Hope this information will be useful for your research of BMPR1A.
BMP2; GDF5; BMP4; BMP2; BMP2; FSTL1; HSP90AB1