BMPR1A

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BMPR1A

Official Full Name bone morphogenetic protein receptor, type IA
Background The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Synonyms BMPR1A; bone morphogenetic protein receptor, type IA; ACVRLK3; bone morphogenetic protein receptor type-1A; ALK3; CD292; ALK-3; BMPR-1A; BMP type-1A receptor; activin receptor-like kinase 3; activin A receptor, type II-like kinase 3; serine/threonine-prot
    • Species :
    • Canine
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Rhesus monkey
    • Source :
    • CHO cells
    • E.coli
    • HEK293
    • Human
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NS0
    • NSO
    • Sf21 Insect Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • Fc
    • Fc Chimera
    • His
    • GST
    • hIgG1
    • hIgG4
    • HIgG
    • SUMO
    • T7
    • human
    • IgG1
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human BMPR1A-32H Recombinant Human BMPR1A Protein CHO cells N/A
    Human BMPR1A-354H Recombinant Human BMPR1A protein, Fc-tagged HEK293 human/IgG1/Fc
    Human BMPR1A-361H Recombinant Human BMPR1A Protein (177-532 aa), His-SUMO-tagged E.coli His/SUMO
    Human BMPR1A-142H Recombinant Human BMPR1A protein, hIgG/His-tagged Insect Cell His/HIgG
    Human BMPR1A-160H Recombinant Human BMPR1A, His-tagged Insect Cell His
    Human BMPR1A-2145HCL Recombinant Human BMPR1A cell lysate Human Cell N/A
    Human BMPR1A-26752TH Recombinant Human BMPR1A Sf9 Insect Cell N/A
    Human BMPR1A-26H Recombinant Human BMP Receptor Type IA, His-tagged His
    Human BMPR1A-2706H Recombinant Human BMPR1A Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human BMPR1A-278H Recombinant Human BMPR1A Protein Wheat Germ N/A
    Human BMPR1A-279H Recombinant Human BMPR1A Protein, GST-tagged Wheat Germ GST
    Human BMPR1A-281H Recombinant Human BMPR1A Protein, GST-tagged Sf21 Insect Cell GST
    Human BMPR1A-28H Recombinant Human BMPR-1A, His-tagged Insect Cell His
    Human BMPR1A-4130H Recombinant Human Bone Morphogenetic Protein Receptor, Type IA Human N/A
    Human BMPR1A-508H Recombinant Human BMPR1A, Fc Chimera NS0 Fc Chimera
    Human BMPR1A-545H Recombinant Human BMPR1A Protein, Fc Chimera NS0 Fc
    Human BMPR1A-553H Recombinant Human BMPR1A, Fc-tagged, Biotinylated Human Cell Fc
    Human BMPR1A-554H Recombinant Human BMPR1A, Fc-tagged Human Cell Fc
    Human BMPR1A-771H Recombinant Human BMPR1A, Fc-His tagged Human Cell Fc/His
    Human BMPR1A-867H Recombinant Human BMPR1A Protein, Fc/His-tagged HEK293 Fc/His
    Human BMPR1A-889H Recombinant Human BMPR1A protein, His-tagged HEK293 His
    Human BMPR1A-991H Recombinant Human Bone Morphogenetic Protein Receptor, Type IA, GST-tagged Sf9 Insect Cell GST
    Mouse Bmpr1a-1709M Recombinant Mouse Bone Morphogenetic Protein Receptor, Type 1A NSO N/A
    Mouse BMPR1A-2466MCL Recombinant Mouse BMPR1A cell lysate Human Cell N/A
    Mouse Bmpr1a-247M Recombinant Mouse Bmpr1a, Fc-His tagged Human Cell Fc/His
    Mouse Bmpr1a-24M Recombinant Mouse Bmpr1a, His tagged Human Cell His
    Mouse Bmpr1a-623M Recombinant Mouse Bmpr1a Protein, Fc Chimera NS0 Fc
    Rat Bmpr1a-576R Recombinant Rat Bmpr1a protein, His & T7-tagged E.coli His/T7
    Rat BMPR1A-999R Recombinant Rat BMPR1A Protein Mammalian Cell His
    Rhesus monkey BMPR1A-1685R Recombinant Rhesus Monkey BMPR1A Protein HEK293 N/A
    Rhesus monkey BMPR1A-1686R Recombinant Rhesus Monkey BMPR1A Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey BMPR1A-1687R Recombinant Rhesus Monkey BMPR1A Protein, hIgG4-tagged HEK293 hIgG4
    Rhesus Macaque BMPR1A-547R Recombinant Rhesus monkey BMPR1A Protein, His-tagged Mammalian Cell His
    Canine BMPR1A-1043C Recombinant Canine BMPR1A Protein, Fc-tagged HEK293 Fc
    Chicken BMPR1A-6909C Recombinant Chicken BMPR1A Mammalian Cell His

    BMPR1A involved in several pathways and played different roles in them. We selected most pathways BMPR1A participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMPR1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction CCR10; IL11; CCL20A.3; BMPR1BB; CXCR4A; OSMR; CCR8L; IL5RA; IL1R2; TNFRSF17
    TGF-beta signaling pathway BMP7B; SPAW; CHRD; TGFB1; ROCK2B; NOG; SMAD3; NDR1; RHOAD; NODAL
    Hippo signaling pathway PPP1CC; MOB1A; GDF5; BMP5; SMAD1; LLGL1; WNT2; RASSF1; BMP8A; CCND1
    Signaling pathways regulating pluripotency of stem cells NEUROG1; WNT9A; FGFR1; FZD9; BMP2; WNT8B; BMPR1A; SMAD2; GRB2; WNT6

    BMPR1A has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by BMPR1A itself. We selected most functions BMPR1A had, and list some proteins which have the same functions with BMPR1A. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding TSSK6; PANK3; CDC42BPG; GAK; OXSR1; KIFC2; TOR2A; KIF1C; HELZ2; DHX57
    RNA polymerase II transcription factor activity, sequence-specific DNA binding ATF4; TFAP2D; JUNBB; ZNF434; BHLHE40; FOXB1A; SOX21; SCAND1; FOXP1; PAX6
    SMAD binding PML; RNF111; SNW1; TGFBR3; COL5A2; SKILB; BMP2; ACVRL1; COL1A2; ACVR1
    glycoprotein binding F7; LCK; LACRT; DNAJC5; SERPINA1E; ITGAM; EDEM2; LDLR; CANX; SERPINA1D
    metal ion binding CASZ1; SPATA21; TATDN3; MAP3K3; ZBTB8A; ZFY1; MIPEP; SP8; SETDB1A; RBM27
    protein binding MBL2; LAMTOR3; C10orf46; PRR3; BTRC; TRPC4AP; EHMT2; USP34; HTT; TCTE3
    protein homodimerization activity CORO1A; GPD1L; MIXL1; TENM3; HAND1; CPNE1; PAH; FGFR1OP2; BAX; BCL2
    protein serine/threonine kinase activity STK24; SMOK2B; DCLK3; TAOK3; CDC42BPA; TESK1; PIK3CG; PLK2B; STK25; TAF1
    receptor signaling protein serine/threonine kinase activity PANK1A; OXSR1B; STK25B; ACVR1BA; STK39; BMPR2B; OXSR1A; ACVR1C; STK25A; PAK2B
    transmembrane receptor protein serine/threonine kinase activity ACVR1BA; BMPR1BA; BMPR2B; BMPR1A; BMPR1AB; ACVR1; ACVR1L; TGFBR2; TGFBR1A; ACVR2AA

    BMPR1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMPR1A here. Most of them are supplied by our site. Hope this information will be useful for your research of BMPR1A.

    BMP2; GDF5; BMP4; BMP2; BMP2; FSTL1; HSP90AB1

    TGF

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