Recombinant Human BMPR1A Protein (177-532 aa), His-SUMO-tagged BMPR1A-361H

Recombinant Human BMPR1A Protein (177-532 aa), His-SUMO-tagged

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Recombinant Human BMPR1A Protein (177-532 aa), His-SUMO-tagged

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Cat.No. : BMPR1A-361H
Product Overview : Recombinant Human BMPR1A Protein (177-532 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Cardiovascular. Protein Description: Partial.
Description : On ligand binding, forms a receptor complex consisting of two type II and two type I transmbrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4. Positively regulates chondrocyte differentiation through GDF5 interaction.
Source : E. coli
Species : Human
Tag : His-SUMO
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 56.6 kDa
Protein length : 177-532 aa
AA Sequence : KHYCKSISSRRRYNR DLEQDEAFIPVGESL KDLIDQSQSSGSGSG LPLLVQRTIAKQIQM VRQVGKGRYGEVWMG KWRGEKVAVKVFFTT EEASWFRETEIYQTV LMRHENILGFIAADI KGTGSWTQLYLITDY HENGSLYDFLKCATL DTRALLKLAYSAACG LCHLHTEIYGTQGKP AIAHRDLKSKNILIK KNGSCCIADLGLAVK FNSDTNEVDVPLNTR VGTKRYMAPEVLDES LNKNHFQPYIMADIY SFGLIIWEMARRCIT GGIVEEYQLPYYNMV PSDPSYEDMREVVCV KRLRPIVSNRWNSDE CLRAVLKLMSECWAH NPASRLTALRIKKTL AKMVESQDVKI
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : BMPR1A bone morphogenetic protein receptor, type IA [ Homo sapiens ]
Official Symbol : BMPR1A
Synonyms : BMPR1A; ACVRLK3; ALK3; CD292; ALK-3; BMPR-1A; SKR5; 10q23del;
Gene ID : 657
mRNA Refseq : NM_004329
Protein Refseq : NP_004320
MIM : 601299
UniProt ID : P36894

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