CD38 Protein, CD38 molecule

CD38

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CD38

Official Full Name CD38 molecule
Background CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase, is a transmembrane glycoprotein found on the surface of some immune cells including plasma cells, activated or immature T and B cells, monocytes, and natural killer cells. CD38 participates in cell adhesion, signal transduction and calcium signaling. It is expressed at high levels in the plasma cell tumor, prostate cancer, stomach cancer, and neuroblastoma. CD38 is used as one of the plasma cell markers and its ligand is CD31 molecules.
Synonyms CD38; CD38 molecule; ADP-ribosyl cyclase 1; CD38H; cADPr hydrolase 1; cyclic ADP-ribose hydrolase 1; CD38 antigen (ADP-ribosyl cyclase / cyclic ADP-ribose hydrolase)
    • Species :
    • Chicken
    • Cynomolgus
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rabbit
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • Avi
    • Flag
    • T7
    • LIgG2b Fc
    • MIgG2a Fc
    • N/A
    • Strep II
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Cynomolgus CD38-1185CA Recombinant Cynomolgus CD38 protein, Fc-tagged, APC labeled HEK293 Fc
    Cynomolgus CD38-1185CP Recombinant Cynomolgus CD38 protein, Fc-tagged, R-PE labeled HEK293 Fc
    Human CD38-361H Recombinant Human CD38 Protein, LIgG2b Fc-tagged, low endotoxin HEK293 LIgG2b Fc
    Human CD38-362H Recombinant Human CD38 Protein, MIgG2a Fc-tagged, low endotoxin HEK293 MIgG2a Fc
    Human CD38-443H Recombinant Human CD38 Protein (Va43-Ile300), His-tagged, Biotinylated HEK293 His
    Human CD38-574HA Recombinant Human CD38 protein, Fc-tagged, APC labeled HEK293 Fc
    Human CD38-574HP Recombinant Human CD38 protein, Fc-tagged, R-PE labeled HEK293 Fc
    Rat Cd38-8742RA Recombinant Rat Cd38 protein, Fc-tagged, APC labeled HEK293 Fc
    Rat Cd38-8742RP Recombinant Rat Cd38 protein, Fc-tagged, R-PE labeled HEK293 Fc
    Human CD38-0797H Recombinant Human CD38 Protein, GST-Tagged Wheat Germ GST
    Human CD38-1557HCL Recombinant Human CD38 cell lysate Human Cell N/A
    Human CD38-1822H Recombinant Human CD38 protein, His & Avi-tagged, Biotinylated HEK293 His/Avi
    Human CD38-27749TH Recombinant Human CD38 Wheat Germ N/A
    Human CD38-573H Recombinant Human CD38, Fc-tagged, Biotinylated Human Cell Fc
    Human CD38-574H Recombinant Human CD38, Fc-tagged Human Cell Fc
    Human CD38-59H Recombinant Human CD38 protein, His-tagged Insect Cell His
    Human CD38-653H Recombinant Human CD38, His tagged Human Cell His
    Human CD38-654H Recombinant Human CD38 protein, His/Flag-tagged HEK293 His/Flag
    Human CD38-655H Recombinant Human CD38 protein, StrepII-tagged HEK293 Strep II
    Human CD38-7614H Recombinant Human CD38 protein, His & T7-tagged E.coli His/T7
    Human CDA087P Recombinant Human CD-38 E.coli N/A
    Mouse CD38-2639MCL Recombinant Mouse CD38 cell lysate Human Cell N/A
    Mouse Cd38-3112M Recombinant Mouse Cd38 protein, His-tagged HEK293 His
    Mouse Cd38-536M Recombinant Mouse Cd38, His-tagged NS0 His
    Mouse Cd38-7615M Recombinant Mouse Cd38 protein, His & T7-tagged E.coli His/T7
    Rat CD38-1249R Recombinant Rat CD38 Protein Mammalian Cell His
    Rat CD38-1259RCL Recombinant Rat CD38 cell lysate Human Cell N/A
    Rat Cd38-7616R Recombinant Rat Cd38 protein, His & T7-tagged E.coli His/T7
    Rat Cd38-8742R Recombinant Rat Cd38, Fc tagged Human Cell Fc
    Rat Cd38-8743R Recombinant Rat Cd38, His tagged Human Cell His
    Cynomolgus Monkey CD38-1185C Recombinant Cynomolgus CD38 Protein, Fc-tagged HEK293 Fc
    Cynomolgus Monkey CD38-1398CCL Recombinant Cynomolgus CD38 cell lysate Human Cell N/A
    Cynomolgus Monkey CD38-388C Recombinant Cynomolgus CD38 Protein, His-tagged Mammalian Cell His
    Cynomolgus CD38-61C Recombinant Cynomolgus CD38 protein, His-tagged HEK293 His
    Rhesus Macaque CD38-737R Recombinant Rhesus monkey CD38 Protein, His-tagged Mammalian Cell His
    Rabbit CD38-1025RCL Recombinant Rabbit CD38 cell lysate Human Cell N/A
    Rabbit CD38-1027R Recombinant Rabbit CD38 Protein, His-tagged HEK293 His
    Chicken CD38-4486C Recombinant Chicken CD38 Mammalian Cell His

    CD38 involved in several pathways and played different roles in them. We selected most pathways CD38 participated on our site, such as Nicotinate and nicotinamide metabolism, Metabolic pathways, Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD38 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Nicotinate and nicotinamide metabolism NUDT12; MIBP2; NT5C2B; NAPRT1; NT5C1B; MIBP; NT5C1BA; NADKB; NT5M; AOX2P
    Metabolic pathways ASAH2; AK9; MVK; ATP5A1; CDA; PKLR; GALNT4; GLYCTK; ATP6AP1; ATP6V1E1B
    Calcium signaling pathway ORAI1; ADORA2B; GNA11A; PHKG2; PHKA1; MYLK; SLC25A6; ATP2B3B; RYR1B; PPP3CCB
    Hematopoietic cell lineage CD3G; IL5; THPO; CD9; IL2RA; CD34; GM-CSF; CD22; IL1R1; IL7
    Oxytocin signaling pathway CACNG6; RYR2; PLCB3; PPP1R12A; CD38; TRPM2; PLCB4; PRKACA; GNAO1; PIK3CD
    Salivary secretion ATP1B1; PRKG1; MUC5B; PRKCG; RYR3; STATH; PLCB4; AMY1A; PLCB1; AMY1B
    Pancreatic secretion RAB8A; PLCB4; SCTR; GNAQ; PRKCB; AMY2A4; ATP2B4; CPB1; CCKAR; PLCB3
    Epstein-Barr virus infection HLA-DPA1; IKBKB; IL10RA; POLR2I; HDAC1; CCNA2; TNFAIP3; ICAM1; CSNK2A2; Fcer2a

    CD38 has several biochemical functions, for example, NAD(P)+ nucleosidase activity, NAD+ nucleosidase activity, phosphorus-oxygen lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CD38 itself. We selected most functions CD38 had, and list some proteins which have the same functions with CD38. You can find most of the proteins on our site.

    Function Related Protein
    NAD(P)+ nucleosidase activity BST1; CD38
    NAD+ nucleosidase activity ART5; CD38; BST1
    phosphorus-oxygen lyase activity BST1; GUCY2E; ADCY1A; CD38; ADCY2B; GC2; GC3; NPR1A; ADCY1B; GUCY2F
    transferase activity TGFBR1A; AANAT1; LIPT2; SAT2B; UGT5A3; CKBB; CRATB; GGCTB; UGT8A; ACAA1A

    CD38 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD38 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD38.

    Schubert, RD; Hu, Y; et al. IFN-beta Treatment Requires B Cells for Efficacy in Neuroautoimmunity. JOURNAL OF IMMUNOLOGY 194:2110-2116(2015).
    Franquesa, M; Mensah, FK; et al. Human Adipose Tissue-Derived Mesenchymal Stem Cells Abrogate Plasmablast Formation and Induce Regulatory B Cells Independently of T Helper Cells. STEM CELLS 33:880-891(2015).

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