Recombinant Human CD38 Protein (ECD), His-tagged(C-ter)
| Cat.No. : | CD38-30H |
| Product Overview : | Recombinant Human CD38 Protein (ECD) with His tag (C-ter) was expressed in HEK293. |
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| Species : | Human |
| Source : | HEK293 |
| Tag : | His |
| Protein Length : | Val43-Ile300 |
| Description : | The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
| Form : | Powder |
| Endotoxin : | Endotoxin level is less than 0.1 EU/μg of the protein, as determined by the LAL test. |
| Purity : | > 95% (by SDS-PAGE) |
| Applications : | Binding, ELISA, SDS-PAGE |
| Notes : | For laboratory research only, not for drug, diagnostic or other use. |
| Storage : | Lyophilized protein should be stored at -20°C or -80°C. After reconstitution, aliquot and store at -20°C for up to one month, at 2-8°C for up to one week. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. |
| Storage Buffer : | PBS (pH 7.4) |
| Reconstitution : | Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water. |
| Gene Name | CD38 CD38 molecule [ Homo sapiens ] |
| Official Symbol | CD38 |
| Synonyms | CD38; CD38 molecule; CD38 antigen (p45); ADP-ribosyl cyclase 1; ADP ribosyl cyclase 1; NAD(+) nucleosidase; cADPr hydrolase 1; cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; T10; |
| Gene ID | 952 |
| mRNA Refseq | NM_001775 |
| Protein Refseq | NP_001766 |
| MIM | 107270 |
| UniProt ID | P28907 |
Not For Human Consumption!
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