fcer2
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  • Official Full Name
  • Fc fragment of IgE, low affinity II, receptor for (CD23)
  • Background
  • CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages.
  • Synonyms
  • CD23; FCE2; CD23A; IGEBF; CLEC4J; low affinity immunoglobulin epsilon Fc receptor; BLAST-2; CD23 antigen; fc-epsilon-RII; lymphocyte IgE receptor; immunoglobulin E-binding factor; C-type lectin domain family 4, member J
Cat.#:FCER2-343RATag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Fcer2 protein, Fc-tagged, APC labeled
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Cat.#:FCER2-343RPTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Fcer2 protein, Fc-tagged, R-PE labeled
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Cat.#:FCER2-5164HTag:His|Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCER2 Protein, His-Avi-tagged, Biotinylated
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Cat.#:FCER2-3984HTag:N/A
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FCER2 Protein
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Cat.#:FCER2-3985HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FCER2 Protein, GST-tagged
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Cat.#:FCER2-238HTag:Strep II
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCER2, StrepII-tagged
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Cat.#:FCER2-27253THTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human FCER2 protein
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Cat.#:FCER2-27296THTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FCER2, GST-tagged
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Cat.#:FCER2-319HTag:DDK
Source (Host):Sf9 cellsSpecies:Human
Product nameRecombinant Human FCER2 Protein, DDK-tagged
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Cat.#:FCER2-4261HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fc Fragment Of LgE, Low Affinity II, Receptor For (CD23)
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Cat.#:FCER2-5163HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCER2, His tagged
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Cat.#:FCER2-343RTag:Fc|His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Fcer2, Fc tagged
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Cat.#:FCER2-4979HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fc Fragment Of IgE, Low Affinity II, Receptor For (CD23)
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Cat.#:FCER2-1814HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human FCER2 cell lysate
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Cat.#:FCER2-1023RCLTag:N/A
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat FCER2 cell lysate
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Cat.#:CDA084PTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CD-23
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Involved Pathway

FCER2 involved in several pathways and played different roles in them. We selected most pathways FCER2 participated on our site, such as Hematopoietic cell lineage, Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCER2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Hematopoietic cell lineage
GM2002; ITGA6; ITGA2B; CSF3R; IL11; IL9R; CD8A; GM13305; CD36; IL3
Epstein-Barr virus infection
POLR2I; PTMA; XPO1; FCER2; POLR1D; RBPJL; CD44; EP300; RELB; HLA-DPB1

Protein Function

FCER2 has several biochemical functions, for example, IgE binding, carbohydrate binding, integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCER2 itself. We selected most functions FCER2 had, and list some proteins which have the same functions with FCER2. You can find most of the proteins on our site.
Function
Related Protein
Function IgE binding
Related Protein FCER2; LGALS3; MS4A2; FCER1A; Fcer2a; CD247L; FCER1G
Function carbohydrate binding
Related Protein LGALSLA; CLEC2B; GANC; KLRD1; HBL4; LGALS3L; CNTN2; SIGLEC11; GFPT2; FBXO2
Function integrin binding
Related Protein NOV; CTGFB; IGF1; COL3A1; CD151; TGFBI; CTGFA; CXADR; LAMB2; S1PR3
Function metal ion binding
Related Protein EXT2; ANKMY2; ZC3H14; ZNF277; COL27A1A; PLAGX; ZFP57; ANKMY2A; B3GAT2; ATP1A1A.3
Function protein binding
Related Protein RARG; KIF27; ARAP1; RBM23; ALDH7A1; C1orf50; FAM32A; MYH7B; APBB1; LYAR

Interacting Protein

FCER2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCER2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FCER2.
ATF7

FCER2 Related Articles

Rogers, AJ; Tantisira, KG; et al. Predictors of poor response during asthma therapy differ with definition of outcome. PHARMACOGENOMICS 10:1231-1242(2009).
Tantisira, K; et al. Genetic variation in FCER2: implications for children with asthma. PHARMACOGENOMICS 9:805-807(2008).