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FCER2

  • Official Full Name

    Fc fragment of IgE, low affinity II, receptor for (CD23)

  • Overview

    CD23, also known as Fc epsilon RII, or FcεRII, is the "low-affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites, and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells, and platelets. There are two forms of CD23: CD23a and CD23b. CD23a is present on follicular B cells, whereas CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils, and macrophages.
  • Synonyms

    CD23; FCE2; CD23A; IGEBF; CLEC4J; low affinity immunoglobulin epsilon Fc receptor; BLAST-2; CD23 antigen; fc-epsilon-RII; lymphocyte IgE receptor; immunoglobulin E-binding factor; C-type lectin domain family 4, member J;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Others
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Rat
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293F
  • Human
  • Human Cell
  • Human Cells
  • In Vitro Cell Free System
  • Mammalian cells
  • Sf9 Insect Cell
  • Wheat Germ
  • DDK
  • Fc
  • GST
  • His
  • His|Avi
  • SUMO
  • N/A
  • N
  • hFc
  • Strep II
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FCER2-3984H Recombinant Human FCER2 Protein Wheat Germ N/A
Human FCER2-27296TH Recombinant Human FCER2, GST-tagged E.coli GST
Human FCER2-319H Recombinant Human FCER2 Protein, DDK-tagged Sf9 Insect Cell DDK
Human FCER2-4979H Recombinant Human Fc Fragment Of IgE, Low Affinity II, Receptor For (CD23) Human N/A
Human FCER2-3985H Recombinant Human FCER2 Protein, GST-tagged Wheat Germ GST
Human FCER2-5163H Recombinant Human FCER2 protein, His-tagged HEK293 His Asp48-Ser321
Human FCER2-4261H Recombinant Human Fc Fragment Of LgE, Low Affinity II, Receptor For (CD23) Human N/A
Human FCER2-27253TH Recombinant Human FCER2 protein E.coli N/A 172
Human FCER2-238H Recombinant Human FCER2, StrepII-tagged Human Cell Strep II 48-321, 274 a.a.
Human FCER2-1814HCL Recombinant Human FCER2 cell lysate Human Cell N/A
Human FCER2-151H Recombinant Human FCER2 Protein, His-tagged Human Cells His
Human FCER2-923H Recombinant Human FCER2 Protein, His-tagged HEK293F N-His Asp48-Ser321
Human FCER2-2892H Recombinant Human FCER2 protein, His-SUMO-tagged E.coli His-SUMO 48-321aa
Human FCER2-2929H Recombinant Human FCER2 Protein (Asp48-Ser321), N-His tagged Mammalian cells N-His Asp48-Ser321
Human FCER2-922H Recombinant Human FCER2 Protein, His-tagged E.coli N-His Glu151-Ser321
Human FCER2-4730HF Recombinant Full Length Human FCER2 Protein In Vitro Cell Free System 348 amino acids
Human FCER2-5164H Active Recombinant Human FCER2 Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
Human CDA084P Recombinant Human CD-23 E.coli N/A
Human FCER2-4733HF Recombinant Full Length Human FCER2 Protein, GST-tagged In Vitro Cell Free System GST 321 amino acids
Human FCER2-031H Recombinant Human FCER2 Protein, His-tagged E.coli His
Human FCER2-539H Recombinant Human FCER2 Protein HEK293 321
Human FCER2-1257H Recombinant Human FCER2 Protein (Asp48-Ser321), N-His tagged E.coli N-His Asp48-Ser321
Rat FCER2-343R Recombinant Rat FCER2 protein(Glu50-Pro331), hFc-tagged HEK293 N-hFc Glu50-Pro331
Rat FCER2-1023RCL Recombinant Rat FCER2 cell lysate Human Cell N/A
Rat FCER2-343RAF647 Recombinant Rat Fcer2 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 542
Rat FCER2-343RAF555 Recombinant Rat Fcer2 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 542
Rat FCER2-343RF Recombinant Rat Fcer2 Protein, Fc-tagged, FITC conjugated HEK293 Fc 542
Rat FCER2-343RAF488 Recombinant Rat Fcer2 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 542
Rat Fcer2-664R Recombinant Rat Fcer2 Protein, His-tagged HEK293F N-His Glu50-Pro331
Rat FCER2-343RA Recombinant Rat Fcer2 protein, Fc-tagged, APC labeled HEK293 Fc
Rat FCER2-343RP Recombinant Rat Fcer2 protein, Fc-tagged, R-PE labeled HEK293 Fc
Homo sapiens (Human) RFL15321HF Recombinant Full Length Human Low Affinity Immunoglobulin Epsilon Fc Receptor(Fcer2) Protein, His-Tagged E.coli expression system His Full Length (1-321)
Mus musculus (Mouse) RFL27932MF Recombinant Full Length Mouse Low Affinity Immunoglobulin Epsilon Fc Receptor(Fcer2) Protein, His-Tagged E.coli expression system His Full Length (1-331)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • FCER2 Related Articles
  • FCER2 Related Research Area

FCER2 involved in several pathways and played different roles in them. We selected most pathways FCER2 participated on our site, such as Hematopoietic cell lineage, Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCER2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Hematopoietic cell lineageHLA-DRA;THPO;ITGA3;CD36;CD8A;IL1R1;ITGA6;MS4A1;IL7R
Epstein-Barr virus infectionTRAF3;HDAC1;MAP2K7;IL10RB;POLR2E;EIF2AK3;IKBKG;POLR2A;FGR

FCER2 has several biochemical functions, for example, IgE binding, carbohydrate binding, integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCER2 itself. We selected most functions FCER2 had, and list some proteins which have the same functions with FCER2. You can find most of the proteins on our site.

Function Related Protein
IgE bindingMS4A2;Fcer2a;LGALS3;CD247L;FCER1A;FCER1G;FCER2
carbohydrate bindingFBXO2;SIGLEC12;KLRC4-KLRK1;LGALSLB;KLRB1F;GANC;LMAN1L;CHI3L1;ILLR3
integrin bindingVWF;ITGA6;FN1;FBN1;COL5A1;ITGA3;TSPAN4;PXN;LYN
metal ion bindingMSRB1A;ZBTB43;ZFP91;CMTM2A;B3GNT1;TTC4;ZNF726;ZNF620;ATP11A
protein bindingOSTF1;RPS6KA1;FOXRED2;PBRM1;BLNK;RIPK1L;DGKQ;UACA;TRAPPC4

FCER2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCER2 here. Most of them are supplied by our site. Hope this information will be useful for your research of FCER2.

ATF7

Rogers, AJ; Tantisira, KG; et al. Predictors of poor response during asthma therapy differ with definition of outcome. PHARMACOGENOMICS 10:1231-1242(2009).
Tantisira, K; et al. Genetic variation in FCER2: implications for children with asthma. PHARMACOGENOMICS 9:805-807(2008).
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