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Recombinant Human FCER2 protein

Cat.No. : FCER2-27253TH
Product Overview : Recombinant Human FCER2 protein was expressed in Escherichia coli.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Source : E.coli
Species : Human
Form : Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4.
Bio-activity : Fully biologically active when compared to standard. The ED50 determined by its ability to induce TNF-alpha production by human PBMCs.
Molecular Mass : Approximately 19.2 kDa, a single non-glycosylated polypeptide chain containing 172 amino acids.
Protein length : 172
AA Sequence : MELQVSSGFVCNTCPEKWINFQRKC YYFGKGTKQWVHARYACDDMEGQLV SIHSPEEQDFLTKHASHTGSWIGLR NLDLKGEFIWVDGSHVDYSNWAPGE PTSRSQGEDCVMMRGSGRWNDAFCD RKLGAWVCDRLATCTPPASEGSAES MGPDSRPDPDGRLPTPSAPLHS
Endotoxin : Less than 0.1 EU/µg of rHusCD23 as determined by LAL method.
Purity : >95% by SDS-PAGE and HPLC analysis.
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Reconstitution : We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions.
Gene Name : FCER2
Official Symbol : FCER2
Synonyms : FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A) , FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2; CD23 antigen; fc-epsilon-RII; lymphocyte IgE receptor; immunoglobulin E-binding factor; C-type lectin domain family 4, member J; FCE2; CD23A; IGEBF;
Gene ID : 2208
mRNA Refseq : NM_001207019
Protein Refseq : NP_001193948
MIM : 151445
UniProt ID : P06734

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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