Recombinant Human FCER2 Protein

• Cat.No.: FCER2-539H
• Product Overview: Recombinant human FCER2 protein without tag was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Source: HEK293
• Species: Human
• Form: Lyophilized
• Protein Length: 321
• AA Sequence: MEEGQYSEIEELPRRRCCRRGTQIV LLGLVTAALWAGLLTLLLLWHWDTT QSLKQLEERAARNVSQVSKNLESHH GDQMAQKSQSTQISQELEELRAEQQ RLKSQDLELSWNLNGLQADLSSFKS QELNERNEASDLLERLREEVTKLRM ELQVSSGFVCNTCPEKWINFQRKCY YFGKGTKQWVHARYACDDMEGQLVS IHSPEEQDFLTKHASHTGSWIGLRN LDLKGEFIWVDGSHVDYSNWAPGEP TSRSQGEDCVMMRGSGRWNDAFCDR KLGAWVCDRLATCTPPASEGSAESM GPDSRPDPDGRLPTPSAPLHS
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) [ Homo sapiens (human) ]
• Official Symbol: FCER2
• Synonyms: FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A) , FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2; CD23 antigen; fc-epsilon-RII; lymphocyte IgE receptor; immunoglobulin E-binding factor; C-type lectin domain family 4, member J; FCE2; CD23A; IGEBF
• Gene ID: 2208
• mRNA Refseq: NM_001207019
• Protein Refseq: NP_001193948
• MIM: 151445
• UniProt ID: P06734