FCGR2B Protein, Fc fragment of IgG, low affinity IIb, receptor (CD32)

FCGR2B

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FCGR2B

Official Full Name Fc fragment of IgG, low affinity IIb, receptor (CD32)
Background The protein encoded by this gene is a low affinity receptor for the Fc region of immunoglobulin gamma complexes. The encoded protein is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE). Several transcript variants encoding different isoforms have been found for this gene.
Synonyms FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); CD32; FCG2; CD32B; FCGR2; IGFR2; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32)
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Avi
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FCGR2B-323H Recombinant Human FCGR2B Protein, His & Avi-tagged, Biotinylated HEK293 His/Avi
    Human FCGR2B-001HCL Recombinant Human FCGR2B cell lysate CHO N/A
    Human FCGR2B-12820H Recombinant Human FCGR2B, GST-tagged E.coli GST
    Human FCGR2B-1988HCL Recombinant Human FCGR2B cell lysate Human Cell N/A
    Human FCGR2B-258H Recombinant Human FCGR2B, His-tagged, Biotinylated HEK293 His
    Human FCGR2B-259H Recombinant Human FCGR2B Protein, His-tagged, Biotinylated HEK293 His
    Human FCGR2B-2962H Recombinant Human FCGR2B, His & AVI tagged Human Cell His/Avi
    Human FCGR2B-3820H Recombinant Human FCGR2B, His-tagged Human Cell His
    Human FCGR2B-383H Recombinant Human Fc fragment of IgG, low affinity IIb, receptor (CD32), His-tagged E.coli His
    Human FCGR2B-3993H Recombinant Human FCGR2B Protein Wheat Germ N/A
    Human FCGR2B-3994H Recombinant Human FCGR2B Protein, GST-tagged Wheat Germ GST
    Human FCGR2B-403H Recombinant Human FCGR2B Protein, His-tagged HEK293 His
    Human FCGR2B-650H Recombinant Human FCGR2B, His tagged Human Cell His
    Human FCGR2B-7279H Recombinant Human FCGR2B, His tagged CHO His
    Mouse Fcgr2b-2968M Recombinant Mouse Fcgr2b, His & AVI Tagged, Biotinylated Human Cell His/Avi
    Mouse Fcgr2b-3994M Recombinant Mouse Fcgr2b, His & AVI tagged Human Cell His/Avi
    Mouse Fcgr2b-633M Recombinant Mouse Fcgr2b Protein, His-tagged NS0 His
    Mouse Fcgr2b-648M Recombinant Mouse Fcgr2b, His tagged Human Cell His
    Rat FCGR2B-1942RCL Recombinant Rat FCGR2B cell lysate Human Cell N/A
    Rat Fcgr2b-4083R Recombinant Rat Fcgr2b, His tagged Human Cell His
    Rat Fcgr2b-7143R Recombinant Rat Fcgr2b protein, His & T7-tagged E.coli His/T7
    Cynomolgus Monkey FCGR2B-1994CCL Recombinant Cynomolgus FCGR2B cell lysate Human Cell N/A
    Cynomolgus Monkey FCGR2B-278C Recombinant Cynomolgus Monkey FCGR2B protein, His-tagged HEK293 His
    Cynomolgus Monkey FCGR2B-2971C Recombinant Cynomolgus FCGR2B protein, His/AVI-tagged HEK293 His/Avi
    Cynomolgus Monkey FCGR2B-2972C Recombinant Cynomolgus FCGR2B, His & AVI tagged Human Cell His/Avi
    Cynomolgus Monkey FCGR2B-4543C Recombinant Cynomolgus FCGR2B protein, His-tagged HEK293 His
    Cynomolgus Monkey FCGR2B-520C Recombinant Cynomolgus FCGR2B Protein, His-tagged Mammalian Cell His
    Rhesus Macaque FCGR2B-1676R Recombinant Rhesus monkey FCGR2B Protein, His-tagged Mammalian Cell His

    FCGR2B involved in several pathways and played different roles in them. We selected most pathways FCGR2B participated on our site, such as Phagosome, Osteoclast differentiation, B cell receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCGR2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phagosome HLA-DRA; CALR; ITGB3B; TUBB5; TLR4BB; ATP6V0A2B; PIK3C3; MRC1; THBS4A; CD209
    Osteoclast differentiation IKBKB; MAPK1; NFATC1; LILRB2; RELA; SIRPG; CYBB; CSF1R; FOSL2; LILRA3
    B cell receptor signaling pathway IKBKG; PPP3R2; INPPL1; NFATC2; BTK; LAT2; BANK1; Cd79a, Cd79b; PILRB; CARD11
    Fc gamma R-mediated phagocytosis RAF1; PIK3R5; FCGR2B; VASP; AKT2; CFL1; RAC1; PLCG2; PIK3R2; LYN
    Staphylococcus aureus infection ITGB2L; HLA-DQA2; C5; C1QC; FCGR2A; FCGR4; HLA-DPA1; Hc; SELPLG; HLA-DRB4
    Tuberculosis IFNGR1; FCGR3B; BCL10; IL10RA; TRADD; FCGR2B; CD14; FCGR4; IFNA6; CLEC4M
    Measles IL4; TNFAIP3; PIK3R1; CCND2; IFNA16; IFNA5; IFNA10; GSK3B; OAS1; FAS

    FCGR2B has several biochemical functions, for example, IgG binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FCGR2B itself. We selected most functions FCGR2B had, and list some proteins which have the same functions with FCGR2B. You can find most of the proteins on our site.

    Function Related Protein
    IgG binding FCGR1B; FCGR2A; FCGR2B; CD247L; FCGRT; PIP; cgr2b; UMOD; FCGR3B; FCGR2C
    protein binding ARF5; CEP70; AMHR2; OGN; PRKD2; KRT4; MSH4; GTF2B; LAMTOR2; MYBBP1A

    FCGR2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FCGR2B here. Most of them are supplied by our site. Hope this information will be useful for your research of FCGR2B.

    PTPN6; IGHG1

    Karpus, ON; Kiener, HP; et al. CD55 deposited on synovial collagen fibers protects from immune complex-mediated arthritis. ARTHRITIS RESEARCH & THERAPY 17:-(2015).
    Lee, CS; Ashton-Key, M; et al. Expression of the inhibitory Fc gamma receptor IIB (FCGR2B, CD32B) on follicular lymphoma cells lowers the response rate to rituximab monotherapy (SAKK 35/98). BRITISH JOURNAL OF HAEMATOLOGY 168:145-148(2015).

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