fgf12
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  • Official Full Name
  • fibroblast growth factor 12
  • Background
  • Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through cell surface receptor tyrosine kinases. There are four members of the FGF receptor family: FGFR1 (flg), FGFR2 (bek, KGFR), FGFR3, and FGFR4. Eac
  • Synonyms
  • FGF12; fibroblast growth factor 12; FGF12B; FHF1; fibroblast growth factor 12B; fibroblast growth factor FGF 12b; fibroblast growth factor homologous factor 1; myocyte activating factor; FHF-1; FGF-12; myocyte-activating factor; fibroblast growth factor F
Cat.#:FGF12-33MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse FGF12 Protein
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Cat.#:FGF12-2020HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF12 Protein, His-tagged
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Cat.#:FGF12-4102HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FGF12 Protein, GST-tagged
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Cat.#:FGF12-127HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fibroblast Growth Factor 12, His-tagged
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Cat.#:FGF12-12862HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF12, GST-tagged
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Cat.#:FGF12-26554THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF12, His-tagged
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Cat.#:FGF12-543HTag:N/A
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human FGF12 protein
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Cat.#:FGF12-5840MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FGF12 Protein
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Cat.#:FGF12-2325RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FGF12 Protein
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Cat.#:FGF12-1694RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FGF12 Protein, His-tagged
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Cat.#:FGF12-434CTag:N/A
Source (Host):E. coliSpecies:Canine
Product nameRecombinant Canine FGF12
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Cat.#:FGF12-6451CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FGF12
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Cat.#:FGF12-6249HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human FGF12 293 Cell Lysate
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Involved Pathway

FGF12 involved in several pathways and played different roles in them. We selected most pathways FGF12 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
MEF2CA; FGF1A; FGFR3; MAPK12A; MAP4K4; TGFB1; CACNG2A; PRKACAA; CACNA2D2; PAK2B
Ras signaling pathway
RASSF1; TEK; MET; PAK6; PAK1; PDGFA; RIN1; PDGFB; GNGT2; FGF17
Rap signaling pathway
KRIT1; SIPA1L2; Itgam&Itgb2; BRAF; PIK3CB; ITGB2L; CALML3; ANGPT4; LCP2; RASGRP3
PIK-Akt signaling pathway
GYS2; RBL2; ITGB5; THBS2; PIK3R2; IGF1; HSP90AB1; FGFR3; LPAR3; PPP2R2D
Regulation of actin cytoskeleton
VCL; RAC3B; ITGB4; ITGA7; ITGA9; FGF1A; INS; KRAS; HRAS; PAK7
Pathways in cancer
KITLG; RALB; MMP9; PIK3R5; PLEKHG5; GNB1; HRAS; ETS1; SMAD3; FGF9
Melanoma
IGF1; PDGFA; PIK3CG; FGF16; FGF2; RB1; CCND1; KRAS; FGF5; FGF17

Protein Function

FGF12 has several biochemical functions, for example, NOT fibroblast growth factor receptor binding, growth factor activity, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF12 itself. We selected most functions FGF12 had, and list some proteins which have the same functions with FGF12. You can find most of the proteins on our site.
Function
Related Protein
Function NOT fibroblast growth factor receptor binding
Related Protein FGF12; FGF14
Function growth factor activity
Related Protein PGF; GDNF; CD320; EFEMP1; PDGFA; NTF4; FGF18A; NODAL; VEGFAA; FGF20A
Function heparin binding
Related Protein SERPINE2; FGFR2; FGFBP3; SFRP1; CTGF; WISP3; CECR1; COL25A1; AAMP; PTN
Function ion channel binding
Related Protein VDAC1; FGF13; CAV3; PKD2; PKD1; ABCC9; SLC8A1; S100A10; PRNP; KCNAB1
Function protein binding
Related Protein ARHGAP1; RLN3; DNTT; EIF3G; LMX1A; HMGB4; WAC; PPARD; SYNE3; TRA2B
Function sodium channel regulator activity
Related Protein SGK1; PTPN3; FXYD7; FXYD2; SCN1B; GPLD1; SGK2; PRSS30; FGF13; CAV3

Interacting Protein

FGF12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FGF12 here. Most of them are supplied by our site. Hope this information will be useful for your research of FGF12.
DCTD; COIL; IKZF1; ZNF460; LZTS2; DACH1; SRPK2; SRPK1