Recombinant Human Fibroblast Growth Factor 12, His-tagged

Cat.No. : FGF12-127H
Product Overview : Recombinant human FGF12 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques,22.6 kDa (201aa).
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Cat. No. : FGF12-127H
Description : FGF12 (Fibroblast growth factor 12) is a member of the FGF superfamily of molecules which currently stands at 22 members. The FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF12 binds to IB2 (islet brain-2), a cellular kinase scaffold, and voltage gated sodium channels and also plays an important role in intracellular signaling and ion exchange.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MESKEPQLKG IVTRLFSQQG YFLQMHPDGT IDGTKDENSD YTLFNLIPVG LRVVAIQGVK ASLYVAMNGE GYLYSSDVFT PECKFKESVF ENYYVIYSST LYRQQESGRA WFLGLNKEGQ IMKGNRVKKT KPSSHFVPKP IEVCMYREQS LHEIGEKQGR SRKSSGTPTM NGGKVVNQDS T
Formulation : Liquid in 20mM Tris pH 7.5, 10% glycerol, 1 mM DTT, 2 mM EDTA
Purity : > 90% by SDS-PAGE
Concentration : 1 mg/ml (determined by Bradford assay)
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : FGF12 fibroblast growth factor 12 [ Homo sapiens ]
Synonyms : FGF-12; FGF12B; FHF-1; FHF1; Fibroblast growth factor homologous factor 1; Myocyte-activating factor; fibroblast growth factor 12; fibroblast growth factor 12B; fibroblast growth factor FGF-12b; FGF12
Gene ID : 2257
mRNA Refseq : NM_004113
Protein Refseq : NP_004104
MIM : 601513
UniProt ID : P61328
Chromosome Location : 3q28
Function : growth factor activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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