Active Recombinant Human FGF12 Protein (Met1-Thr181), C-His tagged, Animal-free, Carrier-free

• Cat.No.: FGF12-105H
• Product Overview: Recombinant Human FGF12 Protein (Met1-Thr181) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Met1-Thr181
• Description: Fibroblast Growth Factors-12 (FGF-12) is a 20.4 kDa member of the fibroblast Growth Factors with 181 amino acid residues. FGF-12 is mainly expressed from inhibitory neurons, oligodendrocyte precursor cells, excitatory neurons, cardiomyocytes. Involved in nervous system development, function, and positive regulation of voltage-gated sodium channel activity. FGF-12 function in the development of the central and peripheral nervous systems, connective tissue of the skeleton, and the myocardia of the heart.
• Form: Lyophilized
• Bio-activity: Measure by its ability to induce 3T3 cells proliferation. The ED50 for this effect is < 2 ng/mL.
• Molecular Mass: The protein has a calculated MW of 21.23 kDa.
  The protein migrates as 21 kDa under reducing condition (SDS-PAGE analysis).
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >98% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: FGF12 fibroblast growth factor 12 [ Homo sapiens (human) ]
• Official Symbol: FGF12
• Synonyms: FGF12; fibroblast growth factor 12; FGF12B; FHF1; fibroblast growth factor 12B; fibroblast growth factor FGF 12b; fibroblast growth factor homologous factor 1; myocyte activating factor; FHF-1; FGF-12; myocyte-activating factor; fibroblast growth factor FGF-12b
• Gene ID: 2257
• mRNA Refseq: NM_004113
• Protein Refseq: NP_004104
• MIM: 601513
• UniProt ID: P61328