Active Recombinant Human FGF12 Protein

Cat.No. : FGF12-026H
Product Overview : The mature recombinant human FGF-12 protein consists of 181 amino acids (1-181) without tag was expressed in E. coli.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This growth factor lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, this protein accumulated in the nucleus, but was not secreted. The specific function of this gene has not yet been determined.
Source : E. coli
Species : Human
Bio-activity : Measured by its binding ability in a functional ELISA. Immobilized rhFGF R4/Fc Chimera at 5 μg/mL (100 μL/well) can bind rhFGF-12 with a linear range of 1.6-100 ng/mL.
Molecular Mass : 22.4 kDa
Product-Related Proteins : 1-181
Endotoxin : < 0.1 EU/μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : At -80 centigrade. Avoid repeated freeze-thaw cycles.
Storage Buffer : PBS
Gene Name : FGF12 fibroblast growth factor 12 [ Homo sapiens (human) ]
Official Symbol : FGF12
Synonyms : FGF12; fibroblast growth factor 12; FHF1; DEE47; EIEE47; FGF12B; fibroblast growth factor 12; Names; fibroblast growth factor 12B; fibroblast growth factor FGF-12b; fibroblast growth factor homologous factor 1; myocyte-activating factor
Gene ID : 2257
mRNA Refseq : NM_021032
Protein Refseq : NP_066360
MIM : 601513
UniProt ID : P61328

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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