gdf9
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  • Official Full Name
  • growth differentiation factor 9
  • Background
  • Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Growth differentiation factor-9 (GDF9) is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9 is a member of the transforming growth factor-beta superfamily.
  • Synonyms
  • GDF9; growth differentiation factor 9; growth/differentiation factor 9; GDF-9
Cat.#:GDF9-4830HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GDF9 Protein, GST-tagged
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Cat.#:GDF9-223HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Growth Differentiation Factor 9, His-tagged
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Cat.#:GDF9-245HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Growth Differentiation Factor 9
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Cat.#:GDF9-999HTag:
Source (Host):HEK293 CellsSpecies:Human
Product nameRecombinant Human GDF9
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Cat.#:Gdf9-180MTag:
Source (Host):CHO cellsSpecies:Mouse
Product nameRecombinant Mouse Gdf9
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Cat.#:GDF9-6290MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GDF9 Protein
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Cat.#:Gdf9-643MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gdf9 Protein, His-tagged
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Cat.#:Gdf9-644RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gdf9 Protein, His-tagged
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Cat.#:GDF9-7111CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken GDF9
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Cat.#:GDF9-2037ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GDF9
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Cat.#:Gdf9-726MTag:N/A
Source (Host):CHOSpecies:Mouse
Product nameRecombinant Mouse Growth Differentiation Factor 9
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Cat.#:GDF9-5966HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GDF9 293 Cell Lysate
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Involved Pathway

GDF9 involved in several pathways and played different roles in them. We selected most pathways GDF9 participated on our site, such as Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ovarian steroidogenesis
ALOX5; HSD17B2; GDF9; CYP2J5; GNAS; PRKACA; PRKACB; CYP2J6; IGF1; HSD17B1

Protein Function

GDF9 has several biochemical functions, for example, cytokine activity, growth factor activity, transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF9 itself. We selected most functions GDF9 had, and list some proteins which have the same functions with GDF9. You can find most of the proteins on our site.
Function
Related Protein
Function cytokine activity
Related Protein GDF10B; Ifnz; TGFB3; CCL19A.1; INHBB; BMP2B; IFNA2; IFNA16; Ccl27a; IL20
Function growth factor activity
Related Protein FGF18B; PDGFA; IL34; SPAW; GDF1; BMP15; NRTN; CNTF; FGF12; PROK1
Function transforming growth factor beta receptor binding
Related Protein TGFB2; BMP5; LFT1; TGFBR3; GDF3; BMP3; LEFTY1; INHBB; SMAD2; BMP7B

Interacting Protein

GDF9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF9 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF9.
TK1; SMN1; PSMD11; DLEU1; KDM1A; PRKRA; GADD45G; S100A8; TDGF1; ANXA7; SAT1; CDKN1A; CDKN2C; SERPINB9; DNM2; RAB27A; FOXG1; SNRPG

GDF9 Related Articles

Pan, B; Toms, D; et al. MicroRNA-378 regulates oocyte maturation via the suppression of aromatase in porcine cumulus cells. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM 308:E525-E534(2015).
Nakamura, T; Iwase, A; et al. CYP51A1 Induced by Growth Differentiation Factor 9 and Follicle-Stimulating Hormone in Granulosa Cells Is a Possible Predictor for Unfertilization. REPRODUCTIVE SCIENCES 22:377-384(2015).