GDF9
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Official Full Name
growth differentiation factor 9
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Overview
Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Growth differentiation factor-9 (GDF9) is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9 is a member of the transforming growth factor-beta superfamily. -
Synonyms
GDF9; growth differentiation factor 9; growth/differentiation factor 9; GDF-9;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Zebrafish
- CHO
- E. coli
- E.coli
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- GDF9 Related Articles
GDF9 involved in several pathways and played different roles in them. We selected most pathways GDF9 participated on our site, such as Ovarian steroidogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with GDF9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
Ovarian steroidogenesis | FSHR;PTGS2;ACOT2;LHCGR;HSD3B1;CYP2J5;IGF1;SCARB1;STAR |
GDF9 has several biochemical functions, for example, cytokine activity, growth factor activity, transforming growth factor beta receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GDF9 itself. We selected most functions GDF9 had, and list some proteins which have the same functions with GDF9. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
cytokine activity | CER1;LFT1;IL11;CSF3;Ifna11;EDN1;IFNG1-1;BMP8A;TNFSF13B |
growth factor activity | MDKB;CSF3;LEP;WISP3;IL5;NDR1;FGF10A;GSDF;PDGFAA |
transforming growth factor beta receptor binding | BMP7A;TGFBR3;MSTNB;BMP15;SMURF2;LEFTY2;LEFTY1;GDF2;TGFB1A |
GDF9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GDF9 here. Most of them are supplied by our site. Hope this information will be useful for your research of GDF9.
TK1; SMN1; PSMD11; DLEU1; KDM1A; PRKRA; GADD45G; S100A8; TDGF1; ANXA7; SAT1; CDKN1A; CDKN2C; SERPINB9; DNM2; RAB27A; FOXG1; SNRPG
- Q&As
- Reviews
Q&As (7)
Ask a questionGDF9 stimulates granulosa cell proliferation and differentiation, essential for healthy ovarian function.
GDF9 interacts with intra-ovarian signaling pathways, coordinating follicle development and ovulation.
Changes in GDF9 expression impact embryonic development and the success of early pregnancy stages.
GDF9 significantly impacts female fertility, affecting egg quality and reproductive potential.
Mutations in GDF9 can lead to ovarian disorders, impacting follicle development and female fertility.
GDF9 is crucial for ovarian follicle growth and oocyte maturation, influencing female fertility.
GDF9 regulates steroid hormone production in ovarian cells, influencing reproductive hormone balance.
Customer Reviews (3)
Write a reviewExpertise in peptide synthesis, accelerates our peptide-related projects.
Swift protein quantification, improves data reliability in our experiments.
Outstanding protein-protein interaction studies, boost our research efforts.
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