IL18RAP

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IL18RAP

Official Full Name interleukin 18 receptor accessory protein
Background The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Synonyms IL18RAP; Accessory protein like; Accessory protein-like; AcPL; CD218 antigen-like family member B; CD218b; CDw218b; I18RA_HUMAN; IL 18RAcP; IL 1R accessory protein like; IL 1R7; IL 1RAcPL; IL-18 receptor accessory protein; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL-1R accessory protein-like; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RAP; IL18Rbeta; Interleukin 18 receptor accessory protein; Interleukin-1 receptor 7; Interleukin-18 receptor accessory protein; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • NS0
    • NSO
    • Tag :
    • Fc
    • His
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL18RAP-1073H Recombinant Human IL18RAP Protein, Fc Chimera NS0 Fc
    Human IL18RAP-1658H Recombinant Human Interleukin 18 Receptor Accessory Protein, Fc-tagged NSO Fc
    Human IL18RAP-1755H Recombinant Human IL18RAP protein, His & GST-tagged E.coli His/GST
    Human IL18RAP-194H Recombinant Human IL18RAP Protein, Fc-tagged HEK293 Fc
    Human IL18RAP-2255H Recombinant Human Interleukin 18 Receptor Accessory Protein, Fc-His Human Cell Fc
    Human IL18RAP-2602HCL Recombinant Human IL18RAP cell lysate Human Cell N/A
    Human IL18RAP-3150H Recombinant Human IL18RAP, His tagged Human Cell His
    Human IL18RAP-880H Recombinant Human IL18RAP Protein, His-tagged HEK293 His
    Human IL18RAP-881H Recombinant Human IL18RAP Protein, Fc/His-tagged HEK293 Fc/His
    Mouse IL18RAP-001MCL Recombinant Mouse IL18RAP cell lysate Insect Cell N/A
    Mouse Il18rap-1756M Recombinant Mouse Il18rap protein, His-tagged E.coli His
    Mouse Il18rap-1757M Recombinant Mouse Il18rap protein, His-tagged E.coli His
    Mouse Il18rap-514M Recombinant Mouse Il18rap, His-tagged Insect Cell His
    Mouse IL18RAP-922M Recombinant Mouse IL18RAP Protein, His-tagged Insect Cell His
    Cynomolgus Monkey IL18RAP-1353CCL Recombinant Cynomolgus IL18RAP cell lysate Human Cell N/A
    Cynomolgus Monkey IL18RAP-8835C Recombinant Cynomolgus IL18RAP, Fc tagged Human Cell Fc
    Cynomolgus Monkey IL18RAP-8836C Recombinant Cynomolgus IL18RAP, His tagged Human Cell His

    IL18RAP involved in several pathways and played different roles in them. We selected most pathways IL18RAP participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with IL18RAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction IL15; IL1RAP; IFNK; CXCL5; IL6R; IL25; OSTN; ACVR1B; GDF5; TNFSF18
    Inflammatory bowel disease (IBD) IL18; IL12A; TLR4; IL23R; IFNGR1; NFATC1; H2-AB1; TGFB1; MAF; TNF

    IL18RAP has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by IL18RAP itself. We selected most functions IL18RAP had, and list some proteins which have the same functions with IL18RAP. You can find most of the proteins on our site.

    Function Related Protein
    receptor activity RRBP1B; CSF2RB; P2RY2; GFRA1A; SV2A; EPHB6; LRRN2; DARC; GRIA2B; TREM2

    IL18RAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL18RAP here. Most of them are supplied by our site. Hope this information will be useful for your research of IL18RAP.

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