il18rap
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  • Official Full Name
  • interleukin 18 receptor accessory protein
  • Background
  • The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
  • Synonyms
  • IL18RAP; Accessory protein like; Accessory protein-like; AcPL; CD218 antigen-like family member B; CD218b; CDw218b; I18RA_HUMAN; IL 18RAcP; IL 1R accessory protein like; IL 1R7; IL 1RAcPL; IL-18 receptor accessory protein; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL-1R accessory protein-like; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RAP; IL18Rbeta; Interleukin 18 receptor accessory protein; Interleukin-1 receptor 7; Interleukin-18 receptor accessory protein; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta
Cat.#:IL18RAP-1073HTag:Fc
Source (Host):NSO CellsSpecies:Human
Product nameRecombinant Human IL18RAP Protein, Fc Chimera
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Cat.#:IL18RAP-1755HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human IL18RAP protein, His & GST-tagged
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Cat.#:IL18RAP-194HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL18RAP Protein, Fc-tagged
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Cat.#:IL18RAP-3150HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL18RAP, His tagged
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Cat.#:IL18RAP-880HTag:His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human IL18RAP Protein, His-tagged
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Cat.#:IL18RAP-881HTag:Fc/His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human IL18RAP Protein, Fc/His-tagged
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Cat.#:Il18rap-1756MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il18rap protein, His-tagged
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Cat.#:Il18rap-1757MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Il18rap protein, His-tagged
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Cat.#:Il18rap-514MTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Il18rap, His-tagged
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Cat.#:IL18RAP-922MTag:His
Source (Host):Baculovirus-Insect cellsSpecies:Mouse
Product nameRecombinant Mouse IL18RAP Protein, His-tagged
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Cat.#:IL18RAP-8835CTag:Fc
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IL18RAP, Fc tagged
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Cat.#:IL18RAP-8836CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IL18RAP, His tagged
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Cat.#:IL18RAP-1658HTag:Fc
Source (Host):NS0Species:Human
Product nameRecombinant Human Interleukin 18 Receptor Accessory Protein, Fc-tagged
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Cat.#:IL18RAP-2255HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human Interleukin 18 Receptor Accessory Protein, Fc-His
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Cat.#:IL18RAP-2602HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human IL18RAP cell lysate
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Cat.#:IL18RAP-001MCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse IL18RAP cell lysate
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Cat.#:IL18RAP-1353CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus IL18RAP cell lysate
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Involved Pathway

IL18RAP involved in several pathways and played different roles in them. We selected most pathways IL18RAP participated on our site, such as Cytokine-cytokine receptor interaction, Inflammatory bowel disease (IBD), which may be useful for your reference. Also, other proteins which involved in the same pathway with IL18RAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cytokine-cytokine receptor interaction
IL13RA1; IL1R2; IL1A; KITLG; IFNA14; GM2002; IL15; CX3CR1; PDGFAB; IFNAR2
Inflammatory bowel disease (IBD)
HLA-DRB3; IL6; TNF; IL5; FOXP3; IL12RB2; IL21; GATA3; IL17A; IL12A

Protein Function

IL18RAP has several biochemical functions, for example, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL18RAP itself. We selected most functions IL18RAP had, and list some proteins which have the same functions with IL18RAP. You can find most of the proteins on our site.
Function
Related Protein
Function receptor activity
Related Protein VMN1R40; VMN1R47; NLGN2A; BTN1A1; NCR3; CD200R4; KIR2DL3; TNFRSF25; CLEC4E; CADM2

IL18RAP Related Gene Family

IL