Recombinant Human IL18RAP Protein (Phe20-Arg356), N-His tagged
|Product Overview :||Recombinant Human CD218b/IL18RAP (Phe20-Arg356) fused with the N-His tag was expressed in E. coli.|
- Gene Information
- Related Products
|Source :||E. coli|
|Form :||Lyophilized powder/frozen liquid|
|Molecular Mass :||40.76 kDa|
|Protein Length :||Phe20-Arg356|
|Purity :||>90% as determined by SDS-PAGE.|
|Notes :||For research use only.|
|Storage :||Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 centigrade for one week.
Store at -20 to -80 centigrade for twelve months from the date of receipt.
|Storage Buffer :||0.01M PBS, pH 7.4, 0.02% NLS|
|Reconstitution :||Reconstitute in sterile water for a stock solution.|
|Shipping :||They are shipped out with dry ice/blue ice unless customers require otherwise.|
|Gene Name :||IL18RAP interleukin 18 receptor accessory protein [ Homo sapiens (human) ]|
|Official Symbol :||IL18RAP|
|Synonyms :||IL18RAP; interleukin 18 receptor accessory protein; interleukin-18 receptor accessory protein; AcPL; CD218b; IL-1R7; IL-1R-7; IL-18RAcP; IL-1RAcPL; IL-18Rbeta; IL-18R-beta; IL-18 receptor beta; interleukin-1 receptor 7; interleukin-18 receptor beta; IL-18 receptor accessory protein; CD218 antigen-like family member B; ACPL; IL18RB; CDw218b; MGC120589; MGC120590;|
|Gene ID :||8807|
|mRNA Refseq :||NM_003853|
|Protein Refseq :||NP_003844|
|UniProt ID :||O95256|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (10)Ask a question
RT-qPCR, immunohistochemistry, and single-cell RNA sequencing characterize IL18RAP expression levels and regulation in diverse cellular contexts.
Animal models, patient samples, and therapeutic interventions elucidate IL18RAP's involvement in immune-related disorders and its potential as a therapeutic target.
Isoform-specific knockdown, mutagenesis, and functional assays delineate IL18RAP isoforms' distinct roles in modulating IL18-mediated responses.
Co-immunoprecipitation assays, FRET studies, and biophysical techniques characterize IL18RAP's interactions with IL18 and IL18R1 partners.
Mass spectrometry, mutagenesis, and functional assays investigate the impact of post-translational modifications on IL18RAP's conformation and function.
Surface plasmon resonance, bio-layer interferometry, and surface plasmon-enhanced fluorescence assays quantify IL18RAP's binding kinetics to IL18 and IL18R1.
siRNA knockdown, CRISPR/Cas9-mediated knockout, and transgenic models unravel IL18RAP's physiological roles and contributions to IL18 signaling.
Single-molecule imaging, super-resolution microscopy, and live-cell imaging visualize the dynamic assembly of IL18 receptor complexes involving IL18RAP.
X-ray crystallography, NMR spectroscopy, and computational modeling reveal IL18RAP's structural interactions with IL18 and IL18R1 domains.
Phosphoprotein analysis, pathway-specific inhibitors, and functional assays dissect IL18RAP's intracellular signaling cascades and its crosstalk with IL18R1.
Customer Reviews (3)Write a review
Effective in signaling studies. -
High specificity. -
Reliable in co-immunoprecipitation. -
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