- Cynomolgus Monkey(1)
- Homo sapiens (Human)(1)
- Human(13)
- Mouse(5)
- Rhesus(2)
Recombinant Human Interleukin 18 Receptor Accessory Protein, Fc-His
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Cat.No. : | IL18RAP-2255H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human Interleukin 18 Receptor Accessory encoding the human IL18RAP (Met 1-Arg 356) was fused with the His-tagged Fc region of human IgG1 at the C- terminus. It is expressed inHuman Cells. |
Description : | Interleukin 18 receptor accessory protein, also known as IL18RAP, IL1R7 and CDw218b, is a single-pass type I membrane protein. It is member of the interleukin-1 receptor family. IL18RAP contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 TIR domain. IL18RAP is strongly expressed in peripheral blood leukocytes, spleen, lung, and, to a lesser extent, in colon. It is not expressed in any other tissue tested. IL18RAP is also strongly expressed in T-cells polarized with IL12 and specifically coexpressed with IL18R1 in Th1 cells. |
Source : | Human Cells. |
Purity : | >95 % as determined by SDS-PAGE. |
Endotoxin : | < 1.0 EU per 1μg of the protein as determined by the LAL method. |
Stability : | Samples are stable for up to twelve months from date of receipt at -700C. |
Predicted N Terminal : | Phe 20. |
Molecular Mass : | The recombinant human IL18RAP /Fc chimera is a disulfide-linked homodimeric protein. The reduced monomer consists of 575 amino acids and has a calculated molecular mass of 65.2 KDa. As a result of glycosylation, the apparent molecular mass of rhIL18RAP/Fc monomer is approximately 80 -90 KDa in reduced SDS-PAGE. |
Formulation : | Supplied as a 0.2μm filtered solution of PBS, pH7.4. |
Reconstitution : | Follow the instructions on the vial. Centrifuge the vial at 40C before opening to recover the entire contents. |
Storage : | Store it under sterile conditions at -700C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | IL18RAP interleukin 18 receptor accessory protein [ Homo sapiens ] |
Synonyms : | IL18RAP; interleukin 18 receptor accessory protein; ACPL; CD218b; IL18RB; CDw218b; MGC120589; MGC120590; IL-18 receptor beta; accessory protein-like; AcPL; IL-18RAcP; IL-18Rbeta; IL-1R7; IL-1RAcPL; OTTHUMP00000161337; CD218 antigen-like family member B; CD218b antigen; IL-18 receptor accessory protein; IL-1R accessory protein-like |
Gene ID : | 8807 |
mRNA Refseq : | NM_003853 |
Protein Refseq : | NP_003844 |
MIM : | 604509 |
UniProt ID : | O95256 |
Chromosome Location : | 2q12 |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | transmembrane receptor activity |
◆ Recombinant Protein
IL18RAP-17H | Recombinant Human IL18RAP Protein, hIgG/His-tagged | +Inquiry |
IL18RAP-880H | Recombinant Human IL18RAP Protein, His-tagged | +Inquiry |
IL18RAP-8835C | Recombinant Rhesus IL18RAP protein, hFc-tagged | +Inquiry |
IL18RAP-1073H | Active Recombinant Human IL18RAP Protein, Fc Chimera | +Inquiry |
IL18RAP-59C | Recombinant Cynomolgus IL18RAP Protein, hFc-tagged | +Inquiry |
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◆ Lysates
IL18RAP-001MCL | Recombinant Mouse IL18RAP cell lysate | +Inquiry |
IL18RAP-1353CCL | Recombinant Cynomolgus IL18RAP cell lysate | +Inquiry |
IL18RAP-2602HCL | Recombinant Human IL18RAP cell lysate | +Inquiry |
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