Recombinant Cynomolgus IL18RAP Protein, hFc-tagged IL18RAP-59C

Recombinant Cynomolgus IL18RAP Protein, hFc-tagged

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Cat.No. : IL18RAP-59C Optional Service: Optional requirements on this protein
Product Overview : Recombinant Cynomolgus IL18RAP Protein, fused to hFc-tag, was expressed in HEK293.
Description : The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Source : HEK293
Species : Human
Tag : hFc
Form : 50 mM Tris, 300 mM NaCl, pH8.5.
Molecular Mass : 66 kDa
AA Sequence : FNISGCSTKK LLWAYSTRSE EEFILFCDLP EPQKSHFCHR SQLSPTQVPD HLPFTDSKDL PDVQWYRQPS NGDPLEDIRK SYPHIIQDKC TLRFLTPGVN NTGSYICRPK MIKSPYDVAC CVKMILEVKP QSNASCENSA SHKQDLLLGS TGSISCPSLS CQSDAQSPEV TWYKNGKLLS MTRSNRIVVD EVYIYHQGTY VCDYTQSDTA SSWTVRAVVQ VRTIVGDTKL KPDILDPVES TLEVELGKPL TISCKARFGF ERVFNPVMKW YIKDADLEWE VSVPEAKSIK STLKDEIIER NIILEKVTQR DLRRTFVCFV QNSIGNTTQS VQLKEKRGVV EPKSSDKTHT CPPCPAPELL GGPSVFLFPP KPKDTLMISR TPEVTCVVVD VSHEDPEVKF NWYVDGVEVH NAKTKPREEQ YNSTYRVVSV LTVLHQDWLN GKEYKCKVSN KALPAPIEKT ISKAKGQPRE PQVYTLPPSR DELTKNQVSL TCLVKGFYPS DIAVEWESNG QPENNYKTTP PVLDSDGSFF LYSKLTVDKS RWQQGNVFSC SVMHEALHNH YTQKSLSLSP GK
Endotoxin : <1EU/ug
Purity : >90%
Storage : Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Concentration : 0.94 mg/ml
SDS-PAGE :

Reducing 12% SDS-PAGE and WB analysis profile of purified IL18RAP-02C (CBB stained).

Gene Name : IL18RAP interleukin 18 receptor accessory protein [ Macaca mulatta (Rhesus monkey) ]
Official Symbol : IL18RAP
Synonyms : ACPL; CD218b; IL-1R7; IL18RB; CDw218b; IL-1R-7; IL-18RAcP; IL-1RAcPL; IL-18Rbeta; IL-18R-beta
Gene ID : 712046
mRNA Refseq : XM_015113031
Protein Refseq : XP_014968517
UniProt ID : H2QIG7
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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