jun
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  • Official Full Name
  • jun proto-oncogene
  • Background
  • Transcription factor AP-1; JUN; AP-1; AP1; c-Jun; jun proto-oncogene; p39; jun oncogene; activator protein 1; proto-oncogene c-Jun; enhancer-binding protein AP1; Jun activation domain binding protein; v-jun sarcoma virus 17 oncogene homolog; v-jun avian sarcoma virus 17 oncogene homolog
  • Synonyms
  • JUN; jun proto-oncogene; jun oncogene ,v jun avian sarcoma virus 17 oncogene homolog ,v jun sarcoma virus 17 oncogene homolog (avian); transcription factor AP-1; AP 1; c Jun; Activator Protein 1; AP 1; AP1; cJun; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN; Jun oncogene; JUN protein; Jun proto oncogene; JUN_HUMAN; JUNC; Oncogene JUN; p39; Proto oncogene c jun; Proto oncogene cJun; Proto-oncogene c-jun; Transcription Factor AP 1; Transcription factor AP-1; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; V jun sarcoma virus 17 oncogene homolog (avian); V-jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog; p39; jun oncogene; OTTHUMP00000010036; activator protein 1; proto-oncogene c-Jun; enhancer-binding protein AP1; Jun activation domain binding protein; v-jun sarcoma virus 17 oncogene homolog; v-jun avian sarcoma virus 17 oncogene homolog; AP1; AP-1; c-Jun
Cat.#:JUN-1027HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Jun Oncogene
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Cat.#:JUN-20HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human jun oncogene, His-tagged
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Cat.#:JUN-105HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human JUN, His-tagged
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Cat.#:JUN-18HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human JUN protein, GST-tagged
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Cat.#:JUN-27752THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN
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Cat.#:JUN-291HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN protein, His/MBP-tagged
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Cat.#:JUN-292HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN protein, His/MBP-tagged
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Cat.#:JUN-4856HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun Proto-Oncogene, GST-tagged
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Cat.#:JUN-646HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun Oncogene, GST-tagged
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Cat.#:JUN-792HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun, His-tagged, 27.3 kDa (261 aa)
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Cat.#:JUN-8483HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN, His-tagged
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Cat.#:JUN-8438MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse JUN Protein
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Cat.#:JUN-3146RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat JUN Protein
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Cat.#:JUN-2335RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey JUN Protein, His-tagged
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Cat.#:JUN-2945CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken JUN
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Cat.#:JUN-10349ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish JUN
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Cat.#:JUN-5095HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human JUN 293 Cell Lysate
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Involved Pathway

JUN involved in several pathways and played different roles in them. We selected most pathways JUN participated on our site, such as AGE/RAGE pathway, ATF-2 transcription factor network, Activated TLR4 signalling, which may be useful for your reference. Also, other proteins which involved in the same pathway with JUN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
AGE/RAGE pathway
MMP13; ATF2; EGFR; AGER; CHUK; LGALS3; JAK2; TIRAP; JUN; DIAPH1
ATF-2 transcription factor network
KAT5; HRK; GADD45A; ATF2; MAPK14; DDIT3; CSRP2; RUVBL2; JUND; KCNA3
Activated TLR4 signalling
RIPK3; MAPKAPK2B; DUSP3B; PELI3; TAB1; UBE2V1; JUN; DUSP6; TLR6; IRAK3
Activation of the AP-1 family of transcription factors
MAPK14; ATF2; JUN
AhR pathway
AHRR; NQO1; CYP1A2; JUND; CDKN1B; CYP1B1; AIP; CDC37; AHR; EGFR
Amphetamine addiction
PPP3CC; PPP3CB; TH; NETO2; SLC14A2; ATF2; GNAS; MAOB; PRKCG; CALM4
Androgen receptor signaling pathway
RNF14; CDKN1A; SMARCE1; RUNX2A; EFCAB6; AES; ETV5A; CMTM2A; CTNNB1; GNB2L1
Apoptosis
FAS; CASP7; PRKACB; DERL3; HRK; STK24B; BOKA; PRKAR2B; HMGB2; BCAP31

Protein Function

JUN has several biochemical functions, for example, DNA binding, GTPase activator activity, HMG box domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JUN itself. We selected most functions JUN had, and list some proteins which have the same functions with JUN. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZNF596; MIER1A; SMARCC1B; MLLT1; POLM; FOXP2; DDX3X; RTEL1; NEUROD6A; NR2F5
Function GTPase activator activity
Related Protein TBC1D8B; ASAP2A; OCRL; RGS16; ELMOD2; STARD8; TBC1D26; TBC1D13; ELMOD1; ARHGAP4A
Function HMG box domain binding
Related Protein JUN; HOXA3; HOXC4; ALX4; GATA3; OLIG2; UTF1; POU3F3; CEBPA; HHEX
Function R-SMAD binding
Related Protein SMAD6; SMAD3; MYOCD; PMEPA1; PPM1A; ZC3H3; RANBP3; SMAD4; ZEB2; PAX6
Function RNA polymerase II activating transcription factor binding
Related Protein CTNNB1; ISL1; NEUROD1; RB1; SIN3A; SETD3; ATF2; BHLHE40; MAD2L2; T
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein FOXI1; ZNF331; TBX20; ZKSCAN3; RBPJB; SIX5; GMEB2; GCM1; ATF7; BCL11A
Function RNA polymerase II distal enhancer sequence-specific DNA binding
Related Protein CDX2; HOXB5; ESRRB; NFATC1; NR1H4; ARID3B; NFE2L2; SFPI1; POU4F1; MEOX2
Function RNA polymerase II transcription factor activity, sequence-specific DNA binding
Related Protein ELF3; MEF2C; ZNF215; SP3; TRP53; JUNB; ZNF488; JUND; TFAP2D; BETA3
Function cAMP response element binding
Related Protein CREB3L3; E4F1; JUN; CREB3L3A; ATF6B; ATF6; CREB3L2; CREB3L3L; ATF2; HMGA2
Function chromatin binding
Related Protein HMG20B; LEF1; MSL1A; MEIS1; ELK1; SMARCD3; POU2F1; SSRP1; RCC1; LRWD1
Function enzyme binding
Related Protein PARP1; EGLN1; HIST1H2AL; MSH2; HIST1H2AE; STC2; PUS7; NOS1; Alb; PLSCR1
Function poly(A) RNA binding
Related Protein MKRN2; PRPF31; PPIL4; PDCD11; MRPL44; FAM103A1; NCBP1; PTPN1; RPL10A; APOBEC3F
Function protein binding
Related Protein CDC42EP5; UQCRB; FBXO5; ZNF83; ATP5A1; TARDBP; IGFBP7; SMPD1; CXCR4; CARS
Function transcription coactivator activity
Related Protein ESR2; ZEB1; ARID1A; RARA; BIRC2; NFKB2; MED31; PSMD9; SUB1; ACTL6B
Function transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Related Protein SOX7; PAX3; MEIS1; PURA; NR5A1; GATA6; NR5A2; SRF; TLE4; FOXP3
Function transcription factor activity, sequence-specific DNA binding
Related Protein ZFP191; ZKSCAN14; FOXO4; PHF1; JUNBB; NR1D1; RUNX2B; ARNTL2; ELF1; TFCP2L1
Function transcription factor binding
Related Protein TNFRSF10A; TBL1X; PSMD4; HES3; PDCD11; BCL3; E2F5; KDM1A; NFATC4; HDAC5
Function transcription regulatory region DNA binding
Related Protein TAF7L; TBP; MLL1; TAF9; ASH2L; KCNA3; SOX6; CDK9; BCL11AA; REST
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein DLX3; SMAD4; NKX2-8; TTC6; DDIT3; NFATC2; MEF2A; CEBPZ; ZIC3; NR1H4
Function transcriptional activator activity, RNA polymerase II transcription factor binding
Related Protein LMO2; NR1H4; GBX2; MIXL1; NKX2; PPARA; CREB1; KLF14; PITX1; KLF4

Interacting Protein

JUN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JUN here. Most of them are supplied by our site. Hope this information will be useful for your research of JUN.
FOS

JUN Related Articles

Toyota, H; Sudo, K; et al. Thy28 protects against anti-CD3-mediated thymic cell death in vivo. APOPTOSIS 20:444-454(2015).
Rodriguez, AM; Davila, MP; et al. Tumor Necrosis Factor alpha Phosphorylates c-Jun N-Terminal Kinase in Stallion Spermatozoa: Effect of Cryopreservation. JOURNAL OF EQUINE VETERINARY SCIENCE 35:206-212(2015).