jun
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  • Official Full Name
  • jun proto-oncogene
  • Background
  • Transcription factor AP-1; JUN; AP-1; AP1; c-Jun; jun proto-oncogene; p39; jun oncogene; activator protein 1; proto-oncogene c-Jun; enhancer-binding protein AP1; Jun activation domain binding protein; v-jun sarcoma virus 17 oncogene homolog; v-jun avian sarcoma virus 17 oncogene homolog
  • Synonyms
  • JUN; jun proto-oncogene; jun oncogene ,v jun avian sarcoma virus 17 oncogene homolog ,v jun sarcoma virus 17 oncogene homolog (avian); transcription factor AP-1; AP 1; c Jun; Activator Protein 1; AP 1; AP1; cJun; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN; Jun oncogene; JUN protein; Jun proto oncogene; JUN_HUMAN; JUNC; Oncogene JUN; p39; Proto oncogene c jun; Proto oncogene cJun; Proto-oncogene c-jun; Transcription Factor AP 1; Transcription factor AP-1; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; V jun sarcoma virus 17 oncogene homolog (avian); V-jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog; p39; jun oncogene; OTTHUMP00000010036; activator protein 1; proto-oncogene c-Jun; enhancer-binding protein AP1; Jun activation domain binding protein; v-jun sarcoma virus 17 oncogene homolog; v-jun avian sarcoma virus 17 oncogene homolog; AP1; AP-1; c-Jun
Cat.#:JUN-1027HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Jun Oncogene
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Cat.#:JUN-20HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human jun oncogene, His-tagged
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Cat.#:JUN-105HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human JUN, His-tagged
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Cat.#:JUN-18HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human JUN protein, GST-tagged
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Cat.#:JUN-27752THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN
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Cat.#:JUN-291HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN protein, His/MBP-tagged
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Cat.#:JUN-292HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN protein, His/MBP-tagged
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Cat.#:JUN-4856HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun Proto-Oncogene, GST-tagged
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Cat.#:JUN-646HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun Oncogene, GST-tagged
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Cat.#:JUN-792HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun, His-tagged, 27.3 kDa (261 aa)
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Cat.#:JUN-8483HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN, His-tagged
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Cat.#:JUN-8438MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse JUN Protein
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Cat.#:JUN-3146RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat JUN Protein
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Cat.#:JUN-2335RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey JUN Protein, His-tagged
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Cat.#:JUN-2945CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken JUN
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Cat.#:JUN-10349ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish JUN
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Cat.#:JUN-5095HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human JUN 293 Cell Lysate
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Involved Pathway

JUN involved in several pathways and played different roles in them. We selected most pathways JUN participated on our site, such as AGE/RAGE pathway, ATF-2 transcription factor network, Activated TLR4 signalling, which may be useful for your reference. Also, other proteins which involved in the same pathway with JUN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
AGE/RAGE pathway
DIAPH1; TIRAP; EGFR; MAPK14; CHUK; AGER; LGALS3; JUN; DDOST; ATF2
ATF-2 transcription factor network
DDIT3; CDK4; KAT5; KCNA3; POU2F1; CBFB; CREB1; ATF2; DUSP5; GADD45A
Activated TLR4 signalling
CHST13; TNIP2; SIGIRR; MAPK14; TIRAP; DUSP4; DUSP3; CHUK; CREB1B; TANK
Activation of the AP-1 family of transcription factors
ATF2; JUN; MAPK14
AhR pathway
PTGES3; AHRR; AHR; NQO1; CDKN1A; AIP; CYP1A2; EGFR; FLG; CDC37
Amphetamine addiction
PPP3CA; GRIN2C; PPP3R2; GRIA3; TH; CALM4; ARC; PRKCA; GRIN3A; PPP1CC
Androgen receptor signaling pathway
CTNNB1; RUNX2A; SMARCE1; EFCAB6; STUB1; HTATIP; PIAS3; TGFB1I1; AES; CREBBP
Apoptosis
Casp3; BMX; MYC; IRF2A; DSG2; AKT2L; DYNLL2; IRAK1; BOKA; CAPN1

Protein Function

JUN has several biochemical functions, for example, DNA binding, GTPase activator activity, HMG box domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JUN itself. We selected most functions JUN had, and list some proteins which have the same functions with JUN. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein IRX5B; ZFP423; EBF4; Rhox5; DMRT2; EF1; ZFP57; ZNF71; ERCC2; ARHGEF38
Function GTPase activator activity
Related Protein RANBP1; GIT2B; GNAQ; STARD8; RALBP1; RAB3GAP2; ARHGDIB; ALDH1A1; RGS10; TIAM2
Function HMG box domain binding
Related Protein HOXC4; PRRX1; CEBPA; ALX4; OLIG2; SP1; EGR2; DLX5; HOXA3; UTF1
Function R-SMAD binding
Related Protein PMEPA1; ZC3H3; PARP1; FOXH1; MEN1; FOS; SMURF1; RANBP3; AXIN1; CTNNB1
Function RNA polymerase II activating transcription factor binding
Related Protein HIPK2; EGR2; JUN; EOMES; CTNNB1; PITX2; RB1; ATF2; SETD3; IFI27
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein MYBL2; MED8; IRF4; SNAI3; NR1H2; PAX8; PPARA; PRDM5; KLF13; POU2F2
Function RNA polymerase II distal enhancer sequence-specific DNA binding
Related Protein NFKB1; ATF2; GZF1; NR5A2; TFAP2C; PROP1; MSC; NFE2L2; RXRB; CDX1
Function RNA polymerase II transcription factor activity, sequence-specific DNA binding
Related Protein PHB; FOXO1B; BMPR1A; MITFA; BETA3; ZNF444; SP1; FOXO3B; ATF5; TAL1
Function cAMP response element binding
Related Protein CREB3L1; CREB3L3A; CREB3; HMGA2; ATF6B; CREB3L4; JUN; CREB3L2; CREB1; CREB3L3L
Function chromatin binding
Related Protein RAG2; PRMT6; POLA1; RNF168; CBX5; MEF2C; MEIS1; BEND6; HDAC5; EGR2
Function enzyme binding
Related Protein SLC12A3; ECM1; JUN; PRMT1; TTN; KPNB1; TH; PRKCD; NCOA1; AKT1
Function poly(A) RNA binding
Related Protein LARP7; RBM26; C2orf15; RPUSD4; EIF5B; SAMD4B; FSCN1; WDR46; DDX42; TUFM
Function protein binding
Related Protein TP53RK; SEC22B; TREX1; THEMIS; UHRF1; CELF1; HLTF; SEMA6A; NXF3; SPERT
Function transcription coactivator activity
Related Protein MMS19; TUBB3; NPM1; YAP1; NEUROD1; FUS; RXRA; MED27; MYOD1; NCOA1
Function transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Related Protein NFATC1; PAX3; PURA; TFAP4; MEF2C; THRA; NKX2-1; CREB1; JUN; RFX1
Function transcription factor activity, sequence-specific DNA binding
Related Protein GLI3; MAFA; ZFP583; ZNF192; NR1D2A; TCF12; PAX3; GTF3A; TLX2; E2F1
Function transcription factor binding
Related Protein KDM1A; NKX2-1; SP1; POU5F1; ESRRB; ETS1; RBL1; PARD6A; CSNK2B; MYBBP1A
Function transcription regulatory region DNA binding
Related Protein SIX1; JUND; HINFP; WNT5A; RFX6; SMARCA2; ZFP335; CARM1; CREB3L1; FOXH1
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein FOXL2; PATZ1; SMAD2; CREB3L1; MESP1; FOXD1; PLAG1; FOS; POU2F3; TFAM
Function transcriptional activator activity, RNA polymerase II transcription factor binding
Related Protein SOX10; PPARA; NKX2-5; FOXH1; JUN; GBX2; CLOCK; LMO2; NR1H4; KLF14

Interacting Protein

JUN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JUN here. Most of them are supplied by our site. Hope this information will be useful for your research of JUN.
FOS

JUN Related Articles

Toyota, H; Sudo, K; et al. Thy28 protects against anti-CD3-mediated thymic cell death in vivo. APOPTOSIS 20:444-454(2015).
Rodriguez, AM; Davila, MP; et al. Tumor Necrosis Factor alpha Phosphorylates c-Jun N-Terminal Kinase in Stallion Spermatozoa: Effect of Cryopreservation. JOURNAL OF EQUINE VETERINARY SCIENCE 35:206-212(2015).