jun
Share
  • Official Full Name
  • jun proto-oncogene
  • Background
  • Transcription factor AP-1; JUN; AP-1; AP1; c-Jun; jun proto-oncogene; p39; jun oncogene; activator protein 1; proto-oncogene c-Jun; enhancer-binding protein AP1; Jun activation domain binding protein; v-jun sarcoma virus 17 oncogene homolog; v-jun avian sarcoma virus 17 oncogene homolog
  • Synonyms
  • JUN; jun proto-oncogene; jun oncogene ,v jun avian sarcoma virus 17 oncogene homolog ,v jun sarcoma virus 17 oncogene homolog (avian); transcription factor AP-1; AP 1; c Jun; Activator Protein 1; AP 1; AP1; cJun; Enhancer Binding Protein AP1; Jun Activation Domain Binding Protein; JUN; Jun oncogene; JUN protein; Jun proto oncogene; JUN_HUMAN; JUNC; Oncogene JUN; p39; Proto oncogene c jun; Proto oncogene cJun; Proto-oncogene c-jun; Transcription Factor AP 1; Transcription factor AP-1; Transcription Factor AP1; V jun avian sarcoma virus 17 oncogene homolog; V jun sarcoma virus 17 oncogene homolog (avian); V-jun avian sarcoma virus 17 oncogene homolog; vJun Avian Sarcoma Virus 17 Oncogene Homolog; p39; jun oncogene; OTTHUMP00000010036; activator protein 1; proto-oncogene c-Jun; enhancer-binding protein AP1; Jun activation domain binding protein; v-jun sarcoma virus 17 oncogene homolog; v-jun avian sarcoma virus 17 oncogene homolog; AP1; AP-1; c-Jun
Cat.#:JUN-1027HTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human Jun Oncogene
+Inquiry
Cat.#:JUN-20HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human jun oncogene, His-tagged
+Inquiry
Cat.#:JUN-105HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human JUN, His-tagged
+Inquiry
Cat.#:JUN-18HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human JUN protein, GST-tagged
+Inquiry
Cat.#:JUN-27752THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN
+Inquiry
Cat.#:JUN-291HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN protein, His/MBP-tagged
+Inquiry
Cat.#:JUN-292HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN protein, His/MBP-tagged
+Inquiry
Cat.#:JUN-4856HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun Proto-Oncogene, GST-tagged
+Inquiry
Cat.#:JUN-646HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun Oncogene, GST-tagged
+Inquiry
Cat.#:JUN-792HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Jun, His-tagged, 27.3 kDa (261 aa)
+Inquiry
Cat.#:JUN-8483HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human JUN, His-tagged
+Inquiry
Cat.#:JUN-8438MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse JUN Protein
+Inquiry
Cat.#:JUN-3146RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat JUN Protein
+Inquiry
Cat.#:JUN-2335RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey JUN Protein, His-tagged
+Inquiry
Cat.#:JUN-2945CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken JUN
+Inquiry
Cat.#:JUN-10349ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish JUN
+Inquiry
Cat.#:JUN-5095HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human JUN 293 Cell Lysate
+Inquiry

Involved Pathway

JUN involved in several pathways and played different roles in them. We selected most pathways JUN participated on our site, such as AGE/RAGE pathway, ATF-2 transcription factor network, Activated TLR4 signalling, which may be useful for your reference. Also, other proteins which involved in the same pathway with JUN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
AGE/RAGE pathway
DDOST; MAPK14; ATF2; EGFR; AGER; JAK2; JUN; DIAPH1; MMP13; LGALS3
ATF-2 transcription factor network
POU2F1; JUN; KCNA3; CREB1; JUND; DUSP10; GADD45A; CSRP2; RUVBL2; CBFB
Activated TLR4 signalling
APPB; PELI1; DUSP4; PELI3; MAP3K8; JUN; TLR6; SAA1; ATF2; TICAM1
Activation of the AP-1 family of transcription factors
JUN; MAPK14; ATF2
AhR pathway
CYP1B1; JUN; JUND; NQO1; PTGES3; CDC37; CYP1A2; AHRR; CYP1A1; EGFR
Amphetamine addiction
SIRT1; GRIA4; CREB3L1; CAMK2A; GNAS; GRIN3A; GRIA1; MAOA; CREB3; PPP3R2
Androgen receptor signaling pathway
STUB1; RNF14; CMTM2A; RANBP9; POU2F1B; TGFB1I1; AES; DAXX; MYST2; CREBBP
Apoptosis
CDK5RAP2; CASP3B; TRAF2; GZME; DBNLA; TNFRSF10B; IRF4; TRP53; CFLARA; HRK

Protein Function

JUN has several biochemical functions, for example, DNA binding, GTPase activator activity, HMG box domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by JUN itself. We selected most functions JUN had, and list some proteins which have the same functions with JUN. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZNF490; ZBED4; DNAJC2; POU2AF1; SP5; TFDP1A; TCF4; JRKL; BEND5; CDX1B
Function GTPase activator activity
Related Protein CDC42EP2; RGS17; ARHGAP17; CDC42EP5; DEPDC1A; BCR; RGS9; RGS5A; TBC1D20; ARHGAP6
Function HMG box domain binding
Related Protein HOXC4; EGR2; CEBPA; DLX5; UTF1; POU3F3; HOXA3; ALX4; MEOX1; PRRX1
Function R-SMAD binding
Related Protein PARP1; JUN; RANBP3; TRIM33; PPM1A; SMURF1; SMAD3; MEN1; MYOCD; ZC3H3
Function RNA polymerase II activating transcription factor binding
Related Protein HNF4A; TBX6; TBX20; LDB1; EGR2; SIN3A; ATF2; CTNNB1; BHLHE40; MAD2L2
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein SPI1; CUX2; POU4F2; IRF1; NKX3-2; GZF1; TFAP2E; AEBP2; SFPI1; FOXL2
Function RNA polymerase II distal enhancer sequence-specific DNA binding
Related Protein SPI1; TFAP2C; NFE2L2; GATA2; BACH1A; PROP1; POU4F1; ZBTB16; BACH2; NR5A2
Function RNA polymerase II transcription factor activity, sequence-specific DNA binding
Related Protein ATF4B2; OVOL1; NHLH2; ZNF131; EPAS1; PAX6B; LMO2; ZNF446; ELK4; GCM1
Function cAMP response element binding
Related Protein HMGA2; CREB3L3; E4F1; ATF6; ATF6B; JUN; CREB3; CREB3L3L; CREB3L3A; CREB3L4
Function chromatin binding
Related Protein POLA1; RUNX2; CDC45; HESX1; NEUROD1; ANKRD17; GLI1; JDP2; STAG1; RAD51
Function enzyme binding
Related Protein HIST1H2AN; HIST1H2AK; HSPA1B; MTA1; TP53; RPA2; UGT1A2; CBX3; GRIN1; CYP2A6
Function poly(A) RNA binding
Related Protein NHP2; MYBBP1A; RPS5; RPS28; DDX39A; SRSF5; ARHGEF1; DIEXF; HTATSF1; DDX54
Function protein binding
Related Protein JMY; RIOK3; RTN4RL2A; NIPBL; BET1; ABLIM3; FASTK; GSS; ASB2; SCFD1
Function transcription coactivator activity
Related Protein PER2; JUP; ATXN7L3; MTDH; TAF11; LPIN3; TAF9; MAX; NCOA1; PML
Function transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
Related Protein OLIG2; SNAI2; GATA6; POU3F3; FOXF1; NKX2-5; CEBPA; USF1; NKX2-1; BHLHE40
Function transcription factor activity, sequence-specific DNA binding
Related Protein POU6F1; GCM1; TBX2A; ZFP184; ZHX3; CLOCK; EGR2B; HSF2; PRDM1A; HOXB8A
Function transcription factor binding
Related Protein PIM1; ESR1; DIP2BA; NCOA2; ERCC3; CXXC5; CCND1; FOS; HDAC4; FIGLA
Function transcription regulatory region DNA binding
Related Protein MEF2C; HNF1A; ARID4A; CREB3L1; ZNF217; NR5A2; RREB1; SREBF1; ASH2L; FOXA1
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein SREBF1; E2F4; FOS; GLI2; JUN; ZSCAN21; TCF4; ETV2; FLI1; NKX2-8
Function transcriptional activator activity, RNA polymerase II transcription factor binding
Related Protein MED12; PITX1; SOX10; PPARA; GBX2; WWP2; NFE2L1; KLF14; FOXH1; NOTCH1

Interacting Protein

JUN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with JUN here. Most of them are supplied by our site. Hope this information will be useful for your research of JUN.
FOS

JUN Related Articles

Toyota, H; Sudo, K; et al. Thy28 protects against anti-CD3-mediated thymic cell death in vivo. APOPTOSIS 20:444-454(2015).
Rodriguez, AM; Davila, MP; et al. Tumor Necrosis Factor alpha Phosphorylates c-Jun N-Terminal Kinase in Stallion Spermatozoa: Effect of Cryopreservation. JOURNAL OF EQUINE VETERINARY SCIENCE 35:206-212(2015).