MPO

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MPO

Official Full Name myeloperoxidase
Background Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq, Jul 2008]
Synonyms MPO; myeloperoxidase;
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Human Cells
    • Human Neutrophil
    • Human Sputum
    • Insect Cell
    • Mammalian Cell
    • NS0
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MPO-51H Recombinant Human MPO Protein, His-tagged Human Cells His
    Mouse Mpo-52M Recombinant Mouse Mpo Protein, His-tagged Human Cells His
    Human MPO-2943H Recombinant Human MPO Protein, GST-tagged E.coli GST
    Human MPO-4004H Recombinant Human MPO Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Mpo-4123M Recombinant Mouse Mpo Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human MPO-527H Recombinant Human MPO Protein (Met1-Ser745), His-tagged Insect Cell His
    Human MPO -27H Native Human Myeloperoxidase Human Sputum N/A
    Human MPO-2636H Recombinant Human MPO protein, His-tagged E.coli His
    Human MPO-29360TH Recombinant Human MPO, GST-tagged E.coli GST
    Human MPO-4234HCL Recombinant Human MPO 293 Cell Lysate HEK293 N/A
    Human MPO-493H Recombinant Human MPO protein, His-tagged HEK293 His
    Human MPO-49H Recombinant Human MPO protein, His-tagged E.coli His
    Human MPO-54H Recombinant Human Myeloperoxidase E.coli His
    Human MPO-5506H Recombinant Human MPO Protein, GST-tagged Wheat Germ GST
    Human MPO-63H Recombinant Human Myeloperoxidase E.coli N/A
    Human MPO-8220H Native Human Neutrophil Myeloperoxidase Human Neutrophil N/A
    Mouse Mpo-2637M Recombinant Mouse Mpo protein, His-tagged E.coli His
    Mouse Mpo-2638M Recombinant Mouse Mpo protein, His-tagged E.coli His
    Mouse Mpo-418M Recombinant Mouse Mpo, His-tagged NS0 His
    Mouse MPO-9990M Recombinant Mouse MPO Protein Mammalian Cell His
    Rat Mpo-2639R Recombinant Rat Mpo protein, His & T7-tagged E.coli His/T7
    Kit-0603 Fluorescent Myeloperoxidase and Chlorination Detection Kit N/A
    Kit-0604 MPO Inhibitor Screening Assay Kit N/A
    Kit-0605 Myeloperoxidase Fluorometric Detection Kit N/A
    Kit-0606 Myeloperoxidase Chlorination Fluorometric Assay Kit N/A
    Kit-0607 Myeloperoxidase Peroxidation Fluorometric Assay Kit N/A
    Kit-1982 Myeloperoxidase Inhibitor Screening Assay Kit N/A
    Kit-1986 Neutrophil Myeloperoxidase Activity Assay Kit N/A
    Kit-2292 Myeloperoxidase (MPO) Colorimetric Activity Assay Kit N/A
    Kit-2293 Myeloperoxidase (MPO) Fluorometric Activity Assay Kit N/A

    MPO involved in several pathways and played different roles in them. We selected most pathways MPO participated on our site, such as Phagosome, Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MPO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Phagosome CANX; CTSL1B; ATP6V1C1; TLR4; THBS3A; FCGR2B; ITGAM; CD209; ACTB1; ATP6AP1B
    Transcriptional misregulation in cancer HIST3H3; Itgam&Itgb2; CEBPE; HMGA2; CCNA1; HDAC1; WHSC1; CLSTN2; PLAT; CD14

    MPO has several biochemical functions, for example, chromatin binding, heme binding, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MPO itself. We selected most functions MPO had, and list some proteins which have the same functions with MPO. You can find most of the proteins on our site.

    Function Related Protein
    chromatin binding L3MBTL1; SOX9; NIPBL; PPARGC1A; YAP1; TGIF1; DNMT3A; TADA2B; CBX7; UBTFL
    heme binding CYP2AA2; HBA-X; GUCY1A3; TDO2B; EIF2AK1; MPO; CYP2P9; CYP7A1; CYP7B1; CYB5D2
    heparin binding IMPG2; THBS4; FGFBP1; PRG2; VTN; LIPI; PF4V1; WISP1B; LPL; WISP1
    metal ion binding ZSCAN12; SMAD5; PLA2G12B; PRDM9; TGFBR1; HDAC9; YDJC; ZFP507; RNF121; SAP30L
    peroxidase activity GPX5; PXDN; PTGS1; GPX1B; PRDX5; GPX7; IPCEF1; GPX4B; PTGS2B; TPO

    MPO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPO here. Most of them are supplied by our site. Hope this information will be useful for your research of MPO.

    Dynll1; ssrna_ug

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