mpo
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  • Official Full Name
  • myeloperoxidase
  • Background
  • Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils. [provided by RefSeq, Jul 2008]
  • Synonyms
  • MPO; myeloperoxidase;
Cat.#:MPO-51HTag:His
Source (Host):Human CellsSpecies:Human
Product nameRecombinant Human MPO Protein, His-tagged
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Cat.#:Mpo-52MTag:His
Source (Host):Human CellsSpecies:Mouse
Product nameRecombinant Mouse Mpo Protein, His-tagged
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Cat.#:MPO-2943HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MPO Protein, GST-tagged
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Cat.#:MPO-527HTag:His
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human MPO Protein (Met1-Ser745), His-tagged
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Cat.#:MPO-5506HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MPO Protein, GST-tagged
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Cat.#:MPO-2636HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MPO protein, His-tagged
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Cat.#:MPO-29360THTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MPO, GST-tagged
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Cat.#:MPO-493HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human MPO protein, His-tagged
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Cat.#:MPO-49HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MPO protein, His-tagged
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Cat.#:MPO-54HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Myeloperoxidase
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Cat.#:MPO-63HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Myeloperoxidase
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Cat.#:Mpo-2637MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Mpo protein, His-tagged
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Cat.#:Mpo-2638MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Mpo protein, His-tagged
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Cat.#:Mpo-418MTag:His
Source (Host):NSO cellsSpecies:Mouse
Product nameRecombinant Mouse Mpo, His-tagged
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Cat.#:MPO-9990MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MPO Protein
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Cat.#:Mpo-2639RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Mpo protein, His & T7-tagged
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Cat.#:MPO -27HTag:N/A
Source (Host):Species:Human
Product nameNative Human Myeloperoxidase
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Cat.#:MPO-8220HTag:N/A
Source (Host):Human neutrophil granulocytes (Buffy Coat)Species:Human
Product nameNative Human Neutrophil Myeloperoxidase
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Cat.#:MPO-4234HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human MPO 293 Cell Lysate
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Cat.#:Kit-0604Tag:
Source (Host):Species:
Product nameMPO Inhibitor Screening Assay Kit
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Cat.#:Kit-0606Tag:
Source (Host):Species:
Product nameMyeloperoxidase Chlorination Fluorometric Assay Kit
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Cat.#:Kit-0607Tag:
Source (Host):Species:
Product nameMyeloperoxidase Peroxidation Fluorometric Assay Kit
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Cat.#:Kit-1982Tag:
Source (Host):Species:
Product nameMyeloperoxidase Inhibitor Screening Assay Kit
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Cat.#:Kit-1986Tag:
Source (Host):Species:
Product nameNeutrophil Myeloperoxidase Activity Assay Kit
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Cat.#:Kit-2292Tag:
Source (Host):Species:
Product nameMyeloperoxidase (MPO) Colorimetric Activity Assay Kit
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Cat.#:Kit-2293Tag:
Source (Host):Species:
Product nameMyeloperoxidase (MPO) Fluorometric Activity Assay Kit
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Cat.#:Kit-0603Tag:
Source (Host):Species:
Product nameFluorescent Myeloperoxidase and Chlorination Detection Kit
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Cat.#:Kit-0605Tag:
Source (Host):Species:
Product nameMyeloperoxidase Fluorometric Detection Kit
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Involved Pathway

MPO involved in several pathways and played different roles in them. We selected most pathways MPO participated on our site, such as Phagosome, Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with MPO were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phagosome
ATP6V0E1; DYNC2H1; TLR4BA; BMA1; FCGR1A; ATP6V0B; BMA2; BLB2; DYNC1I1; FCGR3A
Transcriptional misregulation in cancer
CCNT1; SUPT3H; TSPAN7; TP53; LMO2; DEFA3; ZEB1; Pdgfa&Pdgfb; HIST1H3C; DOT1L

Protein Function

MPO has several biochemical functions, for example, chromatin binding, heme binding, heparin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MPO itself. We selected most functions MPO had, and list some proteins which have the same functions with MPO. You can find most of the proteins on our site.
Function
Related Protein
Function chromatin binding
Related Protein FOS; SKOR2; SOD3; ERG; KDM6B; CHD7; GATA3; NKX2; HMGB2; MEOX1
Function heme binding
Related Protein HMOX1; FA2H; HBG2; CYP2J5; CYP11B1; CYP19A1A; CYP2AA6; CYP51; CYP39A1; NGB
Function heparin binding
Related Protein ITGAM; CHRD; THBS2; ZNF146; FGFRL1; VEGFB; RPL22; CYR61; PDCD5; CECR1
Function metal ion binding
Related Protein SUV39H1A; ENOPH1; ZCCHC16; NT5DC3; SLC8A1; ZFP35; ACSM4; THOP1; ZFP932; E4F1
Function peroxidase activity
Related Protein GPX4B; GPX1A; PTGS2A; EPX; PTGS1; GPX7; DUOX2; MPX; GPX1B; PTGS2B

Interacting Protein

MPO has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MPO here. Most of them are supplied by our site. Hope this information will be useful for your research of MPO.
Dynll1; ssrna_ug