Map2 Protein, microtubule-associated protein 2

Map2

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Map2

Official Full Name microtubule-associated protein 2
Background This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jan 2010]
Synonyms MAP2; microtubule-associated protein 2; MAP2A; MAP2B; MAP2C; MAP-2;
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human MAP2-28460TH Recombinant Human MAP2 Wheat Germ N/A
    Human MAP2-284H Recombinant Human MAP2 Mammalian Cell His
    Human MAP2-4512HCL Recombinant Human MAP2 293 Cell Lysate HEK293 N/A
    Human MAP2-6820H Recombinant Human MAP2 protein, His-tagged E.coli His
    Mouse Map2-6821M Recombinant Mouse Map2 protein, His & GST-tagged E.coli His/GST
    Rat Map2-6822R Recombinant Rat Map2 protein, His & GST-tagged E.coli His/GST

    Map2 involved in several pathways and played different roles in them. We selected most pathways Map2 participated on our site, such as LKB1 signaling events, MAPK Cascade, SIDS Susceptibility Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with Map2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    LKB1 signaling events MAP2; CTSD; MARK2; MARK4; STK11IP; CDC37; SIK3
    MAPK Cascade MBPB; MBP; MAP3K2; MAP2
    SIDS Susceptibility Pathways POU3F2; CDCA7L; CREM; YBX1; TPPP; MECP2; RUNX3; MBD1; CTCF; LMX1B

    Map2 has several biochemical functions, for example, calmodulin binding, dystroglycan binding, microtubule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Map2 itself. We selected most functions Map2 had, and list some proteins which have the same functions with Map2. You can find most of the proteins on our site.

    Function Related Protein
    calmodulin binding SPTBN1; EWSR1; CAMK2D1; CAMK1GA; EPB41; SLC14A2; CAMSAP1; CAMK1GB; MYH1B; ASPM
    dystroglycan binding GYLTL1B; AGR3; AGRN; VCL; DMD; DAG1; MAP2; AGR2; CLASP1
    microtubule binding KIF25; NEFM; CHP1; HDAC6; TXNDC3; MAP1LC3C; MAP6; DNM2; NDEL1B; POLB
    protein binding TLE3; CRB1; KCNJ5; ELANE; SH3GL3; ZC3HC1; DYNLT1; IL6ST; STATH; NHEJ1
    structural molecule activity KRTT1C19E; CLDN10B; NEFMB; KRT82; FGG; TUBA1A; KRT35; TUBB; LCE1D; CLDN12

    Map2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Map2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Map2.

    GRB2; CalpB; JUNB; MDM2; CBFB; SCHIP1; 3',5'-cyclic amp; 8-aha-camp; 8-aha-omethyladenosine; PTBP3; p27958-pro_0000037566

    Cherry, JF; Bennett, NK; et al. Engineered N-cadherin and L1 biomimetic substrates concertedly promote neuronal differentiation, neurite extension and neuroprotection of human neural stem cells. ACTA BIOMATERIALIA 10:4113-4126(2014).
    Liang, CM; Weng, SJ; et al. Neurotrophic and neuroprotective potential of human limbus-derived mesenchymal stromal cells. CYTOTHERAPY 16:1371-1383(2014).

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