Recombinant Mouse C4b Protein, GST-Tagged
Cat.No. : | C4b-0053M |
Product Overview : | Mouse C4b partial ORF (NP_033910.2, 20 a.a. - 119 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. |
Source : | Wheat Germ |
Species : | Mouse |
Tag : | GST |
Molecular Mass : | 36.63 kDa |
AA Sequence : | KPRLLLFSPSVVNLGTPLSVGVQLL DAPPGQEVKGSVFLRNPKGGSCSPK KDFKLSSGDDFVLLSLEVPLEDVRS CGLFDLRRAPHIQLVAQSPWLRNTA |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | C4b complement component 4B (Chido blood group) [ Mus musculus ] |
Official Symbol : | C4b |
Synonyms : | C4B; complement component 4B (Chido blood group); complement C4-B; complement component 4 (within H-2S); complement component 4B (Childo blood group); C4; Ss; |
Gene ID : | 12268 |
mRNA Refseq : | NM_009780 |
Protein Refseq : | NP_033910 |
Products Types
◆ Recombinant Protein | ||
C4B-343H | Recombinant Human C4B Protein, His-tagged | +Inquiry |
C4b-342R | Recombinant Rat C4b Protein, His-tagged | +Inquiry |
C4B-341H | Recombinant Human C4B Protein, His-tagged | +Inquiry |
C4B-340H | Recombinant Human C4B Protein, His-tagged | +Inquiry |
C4B-1147M | Recombinant Mouse C4B Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
C4B-99H | Native Human C4b Binding Protein | +Inquiry |
C4B-1846H | Native Human C4B Protein | +Inquiry |
C4B-10H | Native Human C4B Protein | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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