CD81

  • Official Full Name

    CD81 antigen

  • Overview

    CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1. CD81 is expressed on T and B cells, NK cells, dendritic cells, thymocytes, endothelial cells and fibroblasts. CD81 induces B cell adhesion via the VLA-4
  • Synonyms

    CD81; CD81 antigen; 26 kDa cell surface protein TAPA-1; target of the antiproliferative 1; Tapa1; Tapa-1; Tspan28;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Chicken
  • Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
  • Cynomolgus
  • Human
  • Mouse
  • Pan troglodytes (Chimpanzee)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Saguinus oedipus (Cotton-top tamarin)
  • Zebrafish
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Human cells
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Yeast
  • C
  • His
  • Fc
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|HIgG
  • His|T7
  • SUMO
  • mFc
  • MYC
  • DDK
  • Myc|DDK
  • N/A
  • N
  • Myc
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CD81-01H Active Recombinant Human CD81 Protein, Fc-tagged CHO Fc
Human CD81-0527H Active Recombinant Human CD81 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human CD81-574H Active Recombinant Human CD81 protein, His-Avi&Flag-tagged, Biotinylated(Detergent) Insect Cell His-Avi&Flag Gly 2 - Tyr 236
Human CD81-986H Active Recombinant Human CD81 Full Length Transmembrane protein(VLPs) HEK293 N/A Gly 2 - Tyr 236
Human CD81-247H Recombinant Human CD81 protein, His-tagged HEK293 His Phe113-Lys201
Human CD81-0866H Recombinant Human CD81 Protein, GST-Tagged Wheat Germ GST
Human CD81-619H Recombinant Human CD81 Protein, His-tagged HEK293 His
Human CD81-186H Recombinant Human CD81, Gly&Pro tagged Human Cell Fc
Human CD81-1555H Recombinant Human CD81 protein, His & T7-tagged E.coli His/T7 Phe113~Lys201 (Accession # P60033)
Human CD81-848HCL Recombinant Human CD81 cell lysate Human Cell N/A
Human CD81-5375H Recombinant Human CD81 Protein (Phe113-Lys201), N-Fc tagged Mammalian cells N-Fc Phe113-Lys201
Human CD81-210H Recombinant Human CD81 Protein, C-His-tagged E.coli C-His
Human CD81-3105H Recombinant Human CD81 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CD81-548H-B Recombinant Human CD81 Protein Pre-coupled Magnetic Beads HEK293
Human CD81-214H Recombinant Human CD81 Protein, hIgG-His-tagged Insect Cell His/HIgG 113-201aa
Human CD81-13HFL Active Recombinant Full Length Human CD81 Protein, C-Flag-tagged Mammalian cells Flag
Human CD81-151H Recombinant Human CD81 Protein, His-tagged Human cells His
Human CD81-0268H Recombinant Human CD81 protein, mFc-tagged HEK293 mFc Phe113-Lys201
Human CD81-3465H Recombinant Human CD81 protein, His-tagged E.coli His 114-199 aa
Human CD81-2673H Recombinant Human CD81 protein, His-SUMO-tagged E.coli His-SUMO 113-201aa
Human CD81-548H Recombinant Human CD81 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CD81-1301H Recombinant Human CD81 protein(Phe113-Lys201) HEK293 N/A Phe113-Lys201
Human CD81-1450H Recombinant Human CD81 Protein (Phe113-Lys201), N-His tagged E.coli N-His Phe113-Lys201
Human CD81-5374H Recombinant Human CD81 protein, His-tagged Yeast His 113-201aa
Human CD81-3943H Recombinant Human CD81 protein, His&Myc-tagged E.coli N-His&C-Myc 113-201aa
Mouse CD81-3110M Recombinant Mouse CD81 Protein Mammalian Cell His
Mouse Cd81-906M Recombinant Mouse Cd81 Protein, Fc-tagged HEK293 Fc
Mouse CD81-1469M-B Recombinant Mouse CD81 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cd81-849M Recombinant Mouse Cd81 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse Cd81-329M Recombinant Mouse CD81 Protein, His-tagged HEK293 His Lys106-Lys211
Mouse CD81-400M Recombinant Mouse CD81 Protein (116-201 aa), GST-tagged E.coli GST 116-201 aa
Mouse CD81-1469M Recombinant Mouse CD81 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CD81-1263R Recombinant Rat CD81 Protein Mammalian Cell His
Rat Cd81-1102R Recombinant Rat Cd81 protein, mFc-tagged HEK293 mFc Lys116-Lys201
Rat CD81-921R Recombinant Rat CD81 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat CD81-921R-B Recombinant Rat CD81 Protein Pre-coupled Magnetic Beads HEK293
Rat Cd81-330R Recombinant Rat CD81 Protein HEK293 N/A Lys116-Lys201
Bos taurus (Bovine) RFL33103BF Recombinant Full Length Bovine Cd81 Antigen(Cd81) Protein, His-Tagged E.coli expression system His Full Length (1-236)
Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) RFL30843CF Recombinant Full Length Chlorocebus Aethiops Cd81 Antigen(Cd81) Protein, His-Tagged E.coli expression system His Full Length (1-236)
Cynomolgus CD81-328C Recombinant Cynomolgus CD81 Protein, His-tagged HEK293 His Lys116-Lys201
Pan troglodytes (Chimpanzee) RFL9503PF Recombinant Full Length Pan Troglodytes Cd81 Antigen(Cd81) Protein, His-Tagged E.coli expression system His Full Length (1-236)
Rattus norvegicus (Rat) RFL13776RF Recombinant Full Length Rat Cd81 Antigen(Cd81) Protein, His-Tagged E.coli expression system His Full Length (1-236)
Rhesus Macaque CD81-750R Recombinant Rhesus monkey CD81 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CD81-576R Recombinant Rhesus Macaque CD81 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque CD81-576R-B Recombinant Rhesus Macaque CD81 Protein Pre-coupled Magnetic Beads HEK293
Saguinus oedipus (Cotton-top tamarin) RFL34611SF Recombinant Full Length Saguinus Oedipus Cd81 Protein(Cd81) Protein, His-Tagged E.coli expression system His Full Length (1-236)
Zebrafish CD81-9067Z Recombinant Zebrafish CD81 Mammalian Cell His
Chicken CD81-2225C Recombinant Chicken CD81 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

CD81 involved in several pathways and played different roles in them. We selected most pathways CD81 participated on our site, such as B cell receptor signaling pathway, Malaria, Hepatitis C, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD81 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
B cell receptor signaling pathwayNFATC2;PIK3CG;BLK;BCL10;MAPK1;VAV2;CRKL;ARPC2;PLEKHA2
MalariaLRP1;HBB;THBS2;SDC2;IFNG;VCAM1;ICAM1;HBB-B2;Ccl12
Hepatitis CMAPK11;TBK1;PIK3CA;PIK3R1;IFNA17;CLDN3;CLDN6;CLDN7;CLDN5

CD81 has several biochemical functions, for example, MHC class II protein complex binding, protein binding, transferrin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD81 itself. We selected most functions CD81 had, and list some proteins which have the same functions with CD81. You can find most of the proteins on our site.

Function Related Protein
MHC class II protein complex bindingHLA-DMA;HSPA8;HLA-DOA;HLA-DMB;PKM2;PKM;CD74;HSP90AA1;HSP90AB1
protein bindingACTR3;SETD2;VEGFB;LMAN1;MAGI1;FIGNL1;IGF1R;PODXL2;STX6
transferrin receptor bindingCD81;SNX1;SNX4;HFE;TF;HFE2;SNX2;Trf;RGMA

CD81 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD81 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD81.

p27958-pro_0000037570; SRFBP1; HLA-B; q99ib8-pro_0000045596; TRAF6; JAK3; CSNK2B; ZBTB16

Research Area

Related articles

Xiao, F; Fofana, I; et al. Synergy of entry inhibitors with direct-acting antivirals uncovers novel combinations for prevention and treatment of hepatitis C. GUT 64:483-+(2015).
Meola, A; Tarr, AW; et al. Structural Flexibility of a Conserved Antigenic Region in Hepatitis C Virus Glycoprotein E2 Recognized by Broadly Neutralizing Antibodies. JOURNAL OF VIROLOGY 89:2170-2181(2015).
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