Description : |
CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition. |
Source : |
HEK293 |
Species : |
Cynomolgus |
Tag : |
His |
Predicted N Terminal : |
His |
Form : |
Lyophilized from sterile PBS, pH 7.4. Normally 5 %- 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : |
The recombinant cynomolgus CD81 consists of 105 amino acids and predicts a molecular mass of 11.7 kDa. |
Protein length : |
Lys116-Lys201 |
Endotoxin : |
< 1.0 EU per μg protein as determined by the LAL method. |
Purity : |
> 90 % as determined by SDS-PAGE. |
Storage : |
Samples are stable for up to twelve months from date of receipt at-70 centigrade. Store it under sterile conditions at-20 centigrade to-80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Official Symbol : |
CD81 |
Synonyms : |
CD81;CD81 antigen |