Il12rb2 involved in several pathways and played different roles in them. We selected most pathways Il12rb2 participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Inflammatory bowel disease (IBD), which may be useful for your reference. Also, other proteins which involved in the same pathway with Il12rb2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name |
Pathway Related Protein |
| Cytokine-cytokine receptor interaction |
IL4R; GDF5; TGFB1; IL12RB1; TGFBR2; TNFRSF6B; CRFB4; IL19; KITLGA; Il4ra |
| Jak-STAT signaling pathway |
AOX1; IL2RGA; Ifna11; PIK3R2; IL11RA; EP300; PIK3R1; STAT3; IL13; BCL2 |
| Inflammatory bowel disease (IBD) |
HLA-DOB; IL4; HLA-DRB4; IFNGR1; Il2; IL12B; IL18RAP; NFKB1; IL21; IL13 |
Il12rb2 has several biochemical functions, for example, cytokine receptor activity, protein kinase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Il12rb2 itself. We selected most functions Il12rb2 had, and list some proteins which have the same functions with Il12rb2. You can find most of the proteins on our site.
| Function |
Related Protein |
| cytokine receptor activity |
CRFB4; CD74; CRFB16; CRFB6; IL15RA; IL28RA; Il6ra; IRX1; IL13RA2; IL21R.2 |
| protein kinase binding |
CDKN2C; FBXO5; B4GALT1; DAXX; ACVRL1; AKAP7; CCND3; HDAC7; WAS; PRKCZ |
Il12rb2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il12rb2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Il12rb2.
STAT4; SOCS3
Holle, JU; Gross, WL; et al. Genetic risk factors for vasculitis. INTERNIST 55:128-+(2014).
Cho, S; Kim, J; et al. Immunopathogenic characterization of cutaneous inflammation in Behcet's disease. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY 28:51-57(2014).
