Recombinant Human IL12RB2 protein, His-tagged
Cat.No. : | IL12RB2-3884H |
Product Overview : | Recombinant Human IL12RB2(24-622aa) fused with His tag was expressed in Yeast. |
- Specification
- Gene Information
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Description : | This protein is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coex |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 69.7kD |
Protein length : | 24-622aa |
AA Sequence : | KIDACKRGDVTVKPSHVILLGSTVN ITCSLKPRQGCFHYSRRNKLILYKF DRRINFHHGHSLNSQVTGLPLGTTL FVCKLACINSDEIQICGAEIFVGVA PEQPQNLSCIQKGEQGTVACTWERG RDTHLYTEYTLQLSGPKNLTWQKQC KDIYCDYLDFGINLTPESPESNFTA KVTAVNSLGSSSSLPSTFTFLDIVR PLPPWDIRIKFQKASVSRCTLYWRD EGLVLLNRLRYRPSNSRLWNMVNVT KAKGRHDLLDLKPFTEYEFQISSKL HLYKGSWSDWSESLRAQTPEEEPTG MLDVWYMKRHIDYSRQQISLFWKNL SVSEARGKILHYQVTLQELTGGKAM TQNITGHTSWTTVIPRTGNWAVAVS AANSKGSSLPTRINIMNLCEAGLLA PRQVSANSEGMDNILVTWQPPRKDP SAVQEYVVEWRELHPGGDTQVPLNW LRSRPYNVSALISENIKSYICYEIR VYALSGDQGGCSSILGNSKHKAPLS GPHINAITEEKGSILISWNSIPVQE QMGCLLHYRIYWKERDSNSQPQLCE IPYRVSQNSHPINSLQPRVTYVLWM TALTAAGESSHGNEREFCLQGKAN |
Purity : | >90% ( SDS-PAGE ) |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | Store at -20 centigrade, for extended storage, conserve at -20 centigrade or -80 centigrade. |
Gene Name : | IL12RB2 interleukin 12 receptor, beta 2 [ Homo sapiens ] |
Official Symbol : | IL12RB2 |
Synonyms : | IL12RB2; interleukin 12 receptor, beta 2; interleukin-12 receptor subunit beta-2; IL-12RB2; IL-12R-beta-2; IL-12 receptor beta 2; IL-12R subunit beta-2; IL-12 receptor subunit beta-2; interleukin-12 receptor beta-2 chain; RP11-102M16.1; |
Gene ID : | 3595 |
mRNA Refseq : | NM_001258214 |
Protein Refseq : | NP_001245143 |
MIM : | 601642 |
UniProt ID : | Q99665 |
Chromosome Location : | 1p31.3-p31.2 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; IL12-mediated signaling events, organism-specific biosystem; IL27-mediated signaling events, organism-specific biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
Function : | cytokine receptor activity; protein kinase binding; receptor activity; |
Products Types
◆ Recombinant Protein | ||
IL12RB2-214H | Recombinant Human IL12RB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL12RB2-73H | Recombinant Human IL12RB2 protein, Fc-tagged | +Inquiry |
IL12RB2-3230H | Recombinant Human IL12RB2 Protein, His-tagged | +Inquiry |
IL12RB2-3885H | Recombinant Human IL12RB2 protein, His-tagged | +Inquiry |
IL12RB2-9483H | Active Recombinant Human IL12RB2 Protein, Fc/His-tagged | +Inquiry |
◆ Lysates | ||
IL12RB2-2142MCL | Recombinant Mouse IL12RB2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionCRISPR/Cas9 gene tagging tracks IL12RB2 localization dynamically.
Crosslinking and immunoprecipitation study IL12RB2 dimerization.
ChIP-seq identifies genes under IL12RB2's regulation.
Quantitative RT-PCR validates IL12RB2's impact on gene expression.
Functional assays validate IL12RB2's role in signaling pathways.
Flow cytometry quantifies IL12RB2 expression on specific cell types.
Confocal microscopy visualizes IL12RB2 distribution in cells.
siRNA knockdown reveals IL12RB2's functional significance.
Co-immunoprecipitation unveils IL12RB2's protein interactions.
Co-immunoprecipitation and ELISA assay cytokine interactions with IL12RB2.
Customer Reviews (3)
Write a reviewGood for receptor binding studies.
Consistent in bioactivity.
Suitable for flow cytometry.
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