IL18RAP Protein


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Official Full Name interleukin 18 receptor accessory protein
Background The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Synonyms IL18RAP; Accessory protein like; Accessory protein-like; AcPL; CD218 antigen-like family member B; CD218b; CDw218b; I18RA_HUMAN; IL 18RAcP; IL 1R accessory protein like; IL 1R7; IL 1RAcPL; IL-18 receptor accessory protein; IL-18R-beta; IL-18RAcP; IL-18Rbeta; IL-1R accessory protein-like; IL-1R-7; IL-1R7; IL-1RAcPL; IL18RAP; IL18Rbeta; Interleukin 18 receptor accessory protein; Interleukin-1 receptor 7; Interleukin-18 receptor accessory protein; Interleukin-18 receptor accessory protein-like; Interleukin-18 receptor beta
    • Species :
    • Cynomolgus Monkey
    • Homo sapiens (Human)
    • Human
    • Mouse
    • Rhesus
    • Source :
    • E.coli
    • E.coli expression system
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian cells
    • Tag :
    • Fc
    • His
    • hFc
    • hIgG/His
    • His & Avi
    • GST
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL18RAP-1073H Active Recombinant Human IL18RAP Protein, Fc Chimera Mammalian cells Fc Inquiry
    Mouse Il18rap-514M Active Recombinant Mouse Il18rap, His-tagged Insect Cell His Inquiry
    Mouse IL18RAP-922M Active Recombinant Mouse IL18RAP Protein, His-tagged Insect Cell His Inquiry
    Human IL18RAP-1658H Recombinant Human Interleukin 18 Receptor Accessory Protein, Fc-tagged Mammalian cells Fc Inquiry
    Human IL18RAP-1755H Recombinant Human IL18RAP protein, His & GST-tagged E.coli His/GST Inquiry
    Human IL18RAP-194H Recombinant Human IL18RAP Protein, Fc-tagged HEK293 Fc Inquiry
    Human IL18RAP-2255H Recombinant Human Interleukin 18 Receptor Accessory Protein, Fc-His Human Cell Fc Inquiry
    Human IL18RAP-3150H Recombinant Human IL18RAP, His tagged Human Cell His Inquiry
    Human IL18RAP-880H Recombinant Human IL18RAP Protein, His-tagged HEK293 His Inquiry
    Human IL18RAP-881H Recombinant Human IL18RAP Protein, Fc/His-tagged HEK293 Fc/His Inquiry
    Mouse Il18rap-1756M Recombinant Mouse Il18rap protein, His-tagged E.coli His Inquiry
    Mouse Il18rap-1757M Recombinant Mouse Il18rap protein, His-tagged E.coli His Inquiry
    Rhesus IL18RAP-8835C Recombinant Rhesus IL18RAP protein, hFc-tagged HEK293 hFc Inquiry
    Rhesus IL18RAP-8836C Recombinant Rhesus IL18RAP protein, His-tagged HEK293 His
    Human IL18RAP-2602HCL Recombinant Human IL18RAP cell lysate Human Cell N/A Inquiry
    Mouse IL18RAP-001MCL Recombinant Mouse IL18RAP cell lysate Insect Cell N/A Inquiry
    Cynomolgus Monkey IL18RAP-1353CCL Recombinant Cynomolgus IL18RAP cell lysate Human Cell N/A Inquiry
    Human IL18RAP-17H Recombinant Human IL18RAP Protein, hIgG/His-tagged Insect Cell hIgG/His Inquiry
    Human IL18RAP-1863H Recombinant Human IL18RAP protein, His & Avi-tagged, Biotinylated HEK293 His & Avi Inquiry
    Human IL18RAP-58C Recombinant Cynomolgus IL18RAP Protein, His-tagged HEK293 His Inquiry
    Human IL18RAP-59C Recombinant Cynomolgus IL18RAP Protein, hFc-tagged HEK293 hFc Inquiry
    Homo sapiens (Human) RFL4528HF Recombinant Full Length Human Interleukin-18 Receptor Accessory Protein(Il18Rap) Protein, His-Tagged E.coli expression system His Inquiry

    IL18RAP involved in several pathways and played different roles in them. We selected most pathways IL18RAP participated on our site, such as Cytokine-cytokine receptor interaction, Inflammatory bowel disease (IBD), which may be useful for your reference. Also, other proteins which involved in the same pathway with IL18RAP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction BMPR2B; CCL7; AMHR2; TNFRSF4; CRFB4; Kitl; Flt3l; IL3RA; CXCL14; LTBR
    Inflammatory bowel disease (IBD) IL17A; HLA-DMB; HLA-DPA1; IL13; RORC; IL21R; HLA-DRB5; H2-AB1; HLA-DRB3; HLA-DRA

    IL18RAP has several biochemical functions, for example, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IL18RAP itself. We selected most functions IL18RAP had, and list some proteins which have the same functions with IL18RAP. You can find most of the proteins on our site.

    Function Related Protein
    receptor activity EIF2D; ITGB1B.2; NOTCH1; ANTXR2B; DERL1; Siglece; NRXN3; OR3A2; SLC40A1; CD2

    IL18RAP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IL18RAP here. Most of them are supplied by our site. Hope this information will be useful for your research of IL18RAP.

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