RNASE1
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Official Full Name
ribonuclease, RNase A family, 1 (pancreatic)
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Overview
Ribonuclease A is an endonuclease that catalyses the cleavage of RNA on the 3' side of pyrimidine nucleotides. It acts on single stranded and double stranded RNA -
Synonyms
RNASE1; RNS1; ribonuclease pancreatic; RNase 1; RNase A; ribonuclease A (pancreatic);
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Native Proteins
- Bovine Pancreas
- Cattle
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Human Cell
- Mammalian Cell
- Mammalian cells
- Flag
- GST
- His
- Fc
- Avi
- Myc
- DDK
- Non
- Involved Pathway
- Protein Function
- Interacting Protein
RNASE1 involved in several pathways and played different roles in them. We selected most pathways RNASE1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RNASE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
RNASE1 has several biochemical functions, for example, nucleic acid binding, protein binding, ribonuclease A activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RNASE1 itself. We selected most functions RNASE1 had, and list some proteins which have the same functions with RNASE1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| nucleic acid binding | ZFP354A;BAT1;GLIS2B;USP6;ZFP770;SSX2;ZFP526;SALL1A;EIF3B |
| protein binding | PRDM14;IRF8;MLH1;LEMD3;MAPRE2;PRKD1;TAF10;ALKBH3;DHX38 |
| ribonuclease A activity | EAR4;RNASE2;RNASE4;EAR5;RNASE1 |
RNASE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNASE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNASE1.
RNH1; fam_nucleotide_tamra; Dnajc3; RELA; ocd2; q8d051_yerpe; deoB
- Reviews
- Q&As
Customer Reviews (3)
Write a reviewRNASE1 have strong anti-contamination ability and are not easily contaminated, which ensures the quality of the product.
This stability of RNASE1 is impressive, maintaining stable performance regardless of the environment, demonstrating excellent quality and reliability.
The catalytic activity of RNASE1 is excellent, which can simplify complex chemical reactions and improve yields, and has high scientific research value.
Q&As (6)
Ask a questionThere is a correlation between RNASE1 protein and insulin secretion. Studies have shown that RNASE1 protein can regulate insulin synthesis and secretion by affecting the internal environment of pancreatic islets.
At present, the regulatory mechanism of RNASE1 protein is poorly understood. However, studies have found that some factors such as glucagon and insulin may be involved in regulating the expression and activity of RNASE1 protein.
The RNASE1 protein is thought to have potential for anti-tumor effects. Studies have shown that it can induce apoptosis of tumor cells and inhibit the proliferation and invasion ability of tumor cells.
RNASE1 protein has certain application potential in clinical diagnosis. Its hydrolyzed RNA properties can be used to measure the content and stability of RNA, and then evaluate the condition and treatment effect of certain diseases.
The RNASE1 protein participates in the RNA degradation process in the digestive system by cutting the phosphodiester bond of the RNA molecule and degrading it into shorter RNA fragments.
The main expression and secretion site of RNASE1 protein is the pancreas, while the expression in the gut is relatively low. But in some cases, other nucleases in the gut may perform a similar function.
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