Recombinant Human RNASE1, His-tagged

• Cat.No.: RNASE1-7682H
• Product Overview: Recombinant Human Ribonuclease Pancreatic/RNASE1 is produced with our mammalian Cells expression system in HEK293. The target protein is expressed with sequence (Lys29Thr156) of Human RNASE1 fused with a 6His tag at the Cterminus.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Description: Ribonuclease Pancreatic is a secreted enzyme that belongs to the pancreatic ribonuclease family. RNASE1 is an endonuclease that cleaves internal phosphodiester RNA bonds on the 3"side of pyrimidine bases. RNASE1 prefers poly(C) as a substrate and hydrolyzes 2",3"cyclic nucleotides, with a pH optimum near 8.0. RNASE1 acts on single stranded and double stranded RNA.
• Form: Supplied as a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, 10% Glycerol, pH 7.4
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Notes: For research use only.
• Storage: Store at less than 20°C. stable for 6 months after receipt.Please minimize freezethaw cycles.

Gene Information

• Gene Name: RNASE1 ribonuclease, RNase A family, 1 (pancreatic) [ Homo sapiens ]
• Official Symbol: RNASE1
• Synonyms: RNASE1; ribonuclease, RNase A family, 1 (pancreatic); RNS1; ribonuclease pancreatic; RIB-1; RNase 1; RNase A; HP-RNase; RNase upI-1; ribonuclease 1; ribonuclease A; RIB1; MGC12408
• Gene ID: 6035
• mRNA Refseq: NM_002933
• Protein Refseq: NP_002924
• MIM: 180440
• UniProt ID: P07998
• Chromosome Location: 14q11.1
• Function: endonuclease activity; hydrolase activity; nucleic acid binding; pancreatic ribonuclease activity; protein binding