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SIGLEC6

  • Official Full Name

    sialic acid binding Ig-like lectin 6

  • Synonyms

    SIGLEC6; sialic acid binding Ig-like lectin 6; CD33L, CD33L1; sialic acid-binding Ig-like lectin 6; CD327; OB BP1; SIGLEC 6; CD33 antigen-like 1; obesity-binding protein 1; CD33L; OBBP1; CD33L1; CD33L2; CDW327;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Homo sapiens (Human)
  • Human
  • Rhesus monkey
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • Insect cell
  • Mammalian cells
  • C
  • Fc
  • Avi
  • His
  • Fc|His
  • hFc
  • hIgG1
  • hIgG4
  • human|IgG1|Fc
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SIGLEC6-876H Active Recombinant Human SIGLEC6 Protein, Fc Chimera CHO Fc
Human SIGLEC6-146H Recombinant Human SIGLEC6, Fc tagged Human Cell Fc/His
Human SIGLEC6-59H Recombinant Human SIGLEC6, His-tagged HEK293 His
Human SIGLEC6-795HCL Recombinant Human SIGLEC6 cell lysate Human Cell N/A
Human SIGLEC6-191H Recombinant Human SIGLEC6 Protein, His-tagged E.coli His
Human SIGLEC6-55H Recombinant Human SIGLEC6 Protein, Fc-His-tagged Insect cell Fc/His
Human SIGLEC6-559H Recombinant Human SIGLEC6 protein, His-Avi-tagged HEK293 His-Avi lt contains GIn27-Val331.
Human SIGLEC6-339H Recombinant Human SIGLEC6 protein, Fc-tagged HEK293 human/IgG1/Fc 305
Human SIGLEC6-1952H Recombinant Human SIGLEC6 protein, hFc-tagged HEK293 hFc Gln27-Val331
Human SIGLEC6-446H Recombinant Human SIGLEC6 Protein, Fc-tagged HEK293 Fc 453
Human SIGLEC6-13H Recombinant Human SIGLEC6 Protein (27-347), C-Fc-Avi tagged HEK293 C-Fc-Avi 27-347
Human SIGLEC6-5344H Recombinant Human SIGLEC6 Protein (Gln27-Ser331), C-Fc tagged Mammalian cells C-Fc Gln27-Ser331
Human SIGLEC6-0687H Recombinant Human SIGLEC6 protein, Fc-tagged HEK293 Fc Gln16-Val320
Human SIGLEC6-1086H Recombinant Human SIGLEC6 protein(Gln27-Val331), His-tagged HEK293 C-His Gln27-Val331
Rhesus monkey SIGLEC6-1743R Recombinant Rhesus Monkey SIGLEC6 Protein HEK293 N/A
Rhesus monkey SIGLEC6-1744R Recombinant Rhesus Monkey SIGLEC6 Protein, hIgG1-tagged HEK293 hIgG1
Rhesus monkey SIGLEC6-1745R Recombinant Rhesus Monkey SIGLEC6 Protein, hIgG4-tagged HEK293 hIgG4
Homo sapiens (Human) RFL6654HF Recombinant Full Length Human Sialic Acid-Binding Ig-Like Lectin 6(Siglec6) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (27-453)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SIGLEC6 Related Articles
  • SIGLEC6 Related Research Area

SIGLEC6 involved in several pathways and played different roles in them. We selected most pathways SIGLEC6 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with SIGLEC6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemASB13;RNF19B;SEC24A;UBR1;SLAMF6;KIF5B;CTSC;ITPR2;CD300LG
Immune SystemPJA1;AF251705;TRIM6;IRF6;DYNC1I2;FCN2;CASP4;DEFA6;STUB1
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellSIGLEC9;HCST;CD96;SLAMF6;CLEC2G;LAIR1;CD226;CD200R3;SIGLEC12

SIGLEC6 has several biochemical functions, for example, carbohydrate binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIGLEC6 itself. We selected most functions SIGLEC6 had, and list some proteins which have the same functions with SIGLEC6. You can find most of the proteins on our site.

Function Related Protein
carbohydrate bindingACAN;MAG;NOMO1;MAN2C1;SIGLEC14;CLEC9A;REG3B;PRPS1;GALNT13
protein bindingGBA;ETF1;SPN;TKT;EIF3L;CDC25A;DUSP21;AIDA;RAD51D

SIGLEC6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIGLEC6 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIGLEC6.

TCF4; FHL2; rfbD; y936_yerpe

Charlton, JR; Norwood, VF; et al. Evolution of the urinary proteome during human renal development and maturation: variations with gestational and postnatal age. PEDIATRIC RESEARCH 72:179-185(2012).
Kardava, L; Moir, S; et al. Attenuation of HIV-associated human B cell exhaustion by siRNA down regulation of inhibitory receptors. JOURNAL OF CLINICAL INVESTIGATION 121:2614-2624(2011).
  • Q&As
  • Reviews

Q&As (5)

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What are the future prospects for the clinical application of SIGLEC6 protein? 08/16/2021

The clinical application of SIGLEC6 protein holds promise for advancing the diagnosis, treatment, and monitoring of autoimmune diseases, inflammatory conditions, and cancer, with ongoing research paving the way for potential therapeutic interventions.

Are there any genetic variations in SIGLEC6 protein associated with disease susceptibility? 04/02/2021

Genetic variations in the SIGLEC6 gene have been investigated for their potential association with disease susceptibility, particularly in autoimmune and inflammatory conditions.

How does SIGLEC6 protein interact with other immune receptors? 08/29/2018

SIGLEC6 protein has been shown to interact with other immune receptors, potentially influencing the overall immune response and its contribution to disease pathology.

Can SIGLEC6 protein be targeted for drug development? 06/27/2017

Given its involvement in immune regulation and inflammatory processes, SIGLEC6 protein is a potential target for drug development in the treatment of autoimmune and inflammatory diseases.

Can SIGLEC6 protein be used as a therapeutic target in immunotherapy? 05/17/2016

The potential use of SIGLEC6 protein as a therapeutic target in immunotherapy is an area of active investigation, particularly in the context of modulating immune responses in cancer treatment.

Customer Reviews (3)

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Reviews
10/28/2022

    Their expertise and prompt assistance can effectively address any concerns or challenges that may arise during the experimental process.

    06/30/2022

      In addition to its outstanding quality, the manufacturer of the SIGLEC6 protein provides excellent technical support, which is a valuable asset for researchers

      10/24/2016

        The SIGLEC6 protein is of exceptional quality, making it an ideal choice to meet my experimental requirements.

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