Recombinant Human SIGLEC6 protein, Fc-tagged
Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.
|Product Overview :||Recombinant Human SIGLEC6 protein (Gln16-Val320), fused to human IgG1 Fc tag at C-terminus, was expressed in human 293 cells (HEK293).|
|Description :||Sialic acid-binding Ig-like lectin 6 (SIGLEC6) is also known as CD antigen CD327, CD33 antigen-like 1 (CD33L or CD33L1), Obesity-binding protein 1 (OB-BP1). SIGLEC6 belongs to the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family, which contains two Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. SIGLEC6 mediates sialic-acid dependent binding to cells. SIGLEC6 binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.|
|Tag :||human IgG1 Fc|
|Form :||Lyophilized from 0.22 um filtered solution in 50 mM Tris, 100 mM Glycine, pH7.5, 10% trehalose.|
|Molecular Mass :||The protein has a calculated MW of 60.3 kDa. As a result of glycosylation, the protein migrates as 80-90 kDa under reducing (R) condition, and 160-180 kDa under non-reducing (NR) condition (SDS-PAGE).|
|Protein length :||305|
|Endotoxin :||Less than 1.0 EU per ug by the LAL method.|
|Purity :||>90% as determined by SDS-PAGE.|
For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20 centigrade to -70 centigrade for 12 months in lyophilized state;
-70 centigrade for 3 months under sterile conditions after reconstitution.
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.|
|SDS-PAGE of SIGLEC6-339H :||
Human Siglec-6, Fc Tag on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
|Gene Name :||SIGLEC6|
|Official Symbol :||SIGLEC6|
|Synonyms :||SIGLEC6; sialic acid binding Ig-like lectin 6; CD33L, CD33L1; sialic acid-binding Ig-like lectin 6; CD327; OB BP1; SIGLEC 6; CD33 antigen-like 1; obesity-binding protein 1; CD33L; OBBP1; CD33L1; CD33L2; CDW327|
|Gene ID :||946|
|mRNA Refseq :||NM_001177547|
|Protein Refseq :||NP_001171018|
|UniProt ID :||O43699|
◆ Recombinant Protein
|SIGLEC6-55H||Recombinant Human SIGLEC6 Protein, Fc-His-tagged||+Inquiry|
|SIGLEC6-1745R||Recombinant Rhesus Monkey SIGLEC6 Protein, hIgG4-tagged||+Inquiry|
|SIGLEC6-1744R||Recombinant Rhesus Monkey SIGLEC6 Protein, hIgG1-tagged||+Inquiry|
|SIGLEC6-59H||Recombinant Human SIGLEC6, His-tagged||+Inquiry|
|SIGLEC6-876H||Recombinant Human SIGLEC6 Protein, Fc Chimera||+Inquiry|
|SIGLEC6-795HCL||Recombinant Human SIGLEC6 cell lysate||+Inquiry|